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Neurochemistry of severe dementia

Part of: Bespoke shallow archive Weizmann

Published online by Cambridge University Press:  28 March 2006

Sally I Sharp ,
Paul T Francis  and
Clive G Ballard
Sally I Sharp
Affiliation:
Wolfson Centre for Age-Related Diseases, King's College London, UK
Paul T Francis
Affiliation:
Wolfson Centre for Age-Related Diseases, King's College London, UK
Clive G Ballard
Affiliation:
Wolfson Centre for Age-Related Diseases, King's College London, UK
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Extract

Severe dementia is associated with frequent psychiatric and behavioural disturbances in addition to marked cognitive and functional deficits. Research to determine a neurochemical understanding of dementia over the last three decades has generated therapeutic strategies which improve patients' cognition and activities of daily living. Different key dementia syndromes have been shown to have distinct neurotransmitter biochemical patho-logy, with important implications for therapy. The current review focuses predominantly upon excitatory neurotransmitter systems.

Type
Neuropsychiatry of old age
Information
Reviews in Clinical Gerontology , Volume 15 , Issue 2 , May 2005 , pp. 105 - 123
Copyright
© 2005 Cambridge University Press

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