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Cytogenetics of tumours of the female reproductive tract

Published online by Cambridge University Press:  02 March 2009

Paola Dal Cin  and
Herman Van Den Berghe
Paola Dal Cin*
Affiliation:
Center for Human Genetics, University of Leuven, Belgium
Herman Van Den Berghe
Affiliation:
Center for Human Genetics, University of Leuven, Belgium
*
Paola Dal Cin, Center for Human Genetics, Herestraat 49, B-3000 Leuven, Belgium.
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Extract

Tumours of the reproductive tract present with a great variety and diversity in males as well as in females. They originate from tissues which belong to different embryonic sheets or stem cells, and may appear at various ages, including younger age groups. Some are under hormonal control or influence, others may have a strong environmental component. It is becoming increasingly clear that in tumours, one or more molecular lesions at the DNA level are the causative factor. Their specificity may be very high and may also determine, in part, the phenotype and histology of the proliferation. Discovery of the genes involved was made possible by previous identification of chromosome changes typically occurring in certain tumours.

Type
Articles
Information
Reproductive Medicine Review , Volume 3 , Issue 1 , March 1994 , pp. 1 - 10
Copyright
Copyright © Cambridge University Press 1994

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