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Molecular electrostatic potential of the nucleic acids

Published online by Cambridge University Press:  17 March 2009

Alberte Pullman  and
Bernard Pullman
Alberte Pullman
Affiliation:
Institut de Biologie Physico-Chimique, Laboratoire de Biochimie Théorique associé au C.N.R.S., 13, rue P. et M. Curie – 75005 Paris
Bernard Pullman
Affiliation:
Institut de Biologie Physico-Chimique, Laboratoire de Biochimie Théorique associé au C.N.R.S., 13, rue P. et M. Curie – 75005 Paris
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Extract

It is generally acknowledged that geometrical and conformational properties of biopolymers have an important effect on their biochemical behaviour. It is less easily recognized that these properties depend also on their macromolecular electronic characteristics.

The aim of this review is to demonstrate the significance of such macromolecular electronic effects. Particularly useful for this sake is the recently much developed concept of ‘molecular electrostatic potential’ (MEP) (Scrocco & Tomasi, 1973, 1978) by which is defined the electrostatic (Coulomb) potential created in the neighbouring space by the nuclear charges and the eletronic distribution of a molecule.

Type
Research Article
Information
Quarterly Reviews of Biophysics , Volume 14 , Issue 3 , August 1981 , pp. 289 - 380
Copyright
Copyright © Cambridge University Press 1981

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