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The structure of branched DNA species

Published online by Cambridge University Press:  17 March 2009

David M. J. Lilley  and
Robert M. Clegg
David M. J. Lilley
Affiliation:
CRC Nucleic Acid Structure Group, Department of Biochemistry, The University, Dundee DD1 4HN, U.K.
Robert M. Clegg
Affiliation:
Abteilung Molekulare Biologie, Max-Planck-Institut für Biophysikalische Chemie, Am Fassberg, D-3400 Göttingen, Federal Republic of Germany
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Extract

Branched DNA molecules provide a challenging set of structural problems. Operationally we define branched DNA species as molecules in which double helical segments are interrupted by abrupt discontinuities, and we draw together a number of different kinds of structure in the class, including helical junctions of different orders, and base bulges (Fig. 1).

Type
Research Article
Information
Quarterly Reviews of Biophysics , Volume 26 , Issue 2 , May 1993 , pp. 131 - 175
Copyright
Copyright © Cambridge University Press 1993

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