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Maternal knowledge, attitude and practice regarding folic acid intake during the periconceptional period

Published online by Cambridge University Press:  02 January 2007

S Sen ,
A Manzoor ,
M Deviasumathy  and
Cindy Newton
S Sen*
Affiliation:
Department of Paediatrics, Queen's Hospital, Burton, Belvedere Road, Burton on Trent, Staffordshire, DE13 0RB, UK:
A Manzoor
Affiliation:
Department of Paediatrics, Queen's Hospital, Burton, Belvedere Road, Burton on Trent, Staffordshire, DE13 0RB, UK:
M Deviasumathy
Affiliation:
Department of Paediatrics, Queen's Hospital, Burton, Belvedere Road, Burton on Trent, Staffordshire, DE13 0RB, UK:
Cindy Newton
Affiliation:
Department of Clinical Audit, Queen's Hospital, Burton, Belvedere Road, Burton on Trent, Staffordshire, DE13 0RB, UK
*
*Corresponding author: Email [email protected]
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Abstract

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Objective:

To study the knowledge, attitude and practice of pregnant women regarding periconceptional folic acid (FA) intake.

Design:

Questionnaire-based prospective study.

Setting:

Antenatal clinic of a District General Hospital.

Subjects:

Three-hundred pregnant women in an antenatal clinic.

Results:

Nearly all (298/300) had heard of FA. A majority (275/300, 91%) knew that FA could prevent neural tube defects, and married women (P <0.001), those with higher education (P <0.001), those of Social Classes 1–3 (P <0.01) and women over 30 years of age (P <0.05) were more likely to be thus aware. Knowledge about the correct timing of FA intake was seen in 76% and was more likely in those with higher education (P <0.001), married women (P <0.001) and women age over 30 years (P <0.05). Intake of FA in the periconceptional period was seen in 134/300 (44.6%) women and was most likely in the married, Social Classes 1–3, women with higher education (all P <0.001), non-smokers (P <0.01), women with a planned pregnancy and women aged 30 years and over (P <0.05).

Conclusions:

The knowledge of the correct timing of FA intake was present in only 76%. Less than half (44.6%) had taken FA in the periconceptional period, and this was far more common in the more ‘privileged’ classes. Low socio-economic status, age less than 30 years, lower educational status and unplanned pregnancy were high risk factors for not taking FA. The challenge to the medical profession for targeting this group cannot be over-emphasised.

Keywords

Folic acidNeural tube defectsProphylaxis
Type
Research Article
Information
Public Health Nutrition , Volume 4 , Issue 4 , August 2001 , pp. 909 - 912
Copyright
Copyright © CABI Publishing 2001

References

1Hibbard, ED, Smithells, RW. Folic acid metabolism and human embryopathy. Lancet 1965; 1: 1254–6.CrossRefGoogle Scholar
2Smithells, RW, Sheppard, S, Schorah, CJ, et al. Possible prevention of neural tube defects by periconceptional folic vitamin supplementation. Lancet 1980; 1: 339–40.CrossRefGoogle ScholarPubMed
3MRC Vitamin Study Research Group. Prevention of neural tube defects. Results of the Medical Research Council vitamin study. Lancet 1991; 338: 131–7.Google Scholar
4Czeizel, AE, Dundas, I. Prevention of the first occurrence of neural tube defects by periconceptional folic acid. N. Engl. J. Med. 1992; 327: 1832–35.Google Scholar
5Department of Health. Folic Acid and the Prevention of Neural Tube Defects. Report from an Expert Advisory Group. Heywood: Department of Heath Publications Unit, 1992.Google Scholar
6Centers for Disease Control. Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects. Morbidity Mortality Weekly Rep. 1992; 41(RR-14), 1–7.Google Scholar
7Smith, RB, Davies, N, Davies, J. Prevention of neural tube defects. Lancet 1994; 343: 123–4.Google Scholar
8Sutcliffe, M, Schorah, CJ, Perry, A, Wild, J. Prevention of neural tube defects. Lancet 1993; 342: 1174.CrossRefGoogle ScholarPubMed
9 Anon. Knowledge and use of folic acid by women of childbearing age – United States 1995. Morbidity Mortality Weekly Rep. 1995; 44: 716–8.Google Scholar
10Sayers, G, Scallan, E, McDonnell, R, Johnson, Z. Knowledge and use of periconceptional folic acid among antenatal patients. Irish Med. J. 1997; 90(6): 236–8.Google ScholarPubMed
11Mathews, F, Yudkin, P, Neil, A. Folates in the periconceptional period: are women getting enough? Br. J. Obstet. Gynaecol. 1998; 105(9), 954–9.CrossRefGoogle Scholar
12McDonnell, R, Johnson, Z, Doyle, A, Sayers, G. Determinants of folic acid knowledge and use among antenatal women. J. Publ. Health Med. 1999; 21: 145–9.CrossRefGoogle ScholarPubMed
13Sayers, GM, Hughes, N, Scallan, E, Johnson, Z. A survey of knowledge and use of folic acid among women of child-bearing age in Dublin. J. Publ. Health Med. 1997; 19: 328–32.CrossRefGoogle ScholarPubMed
14Clark, NIA, Fisk, NM. Minimal compliance with the Department of Health recommendations for routine folate prophylaxis to prevent neural defects. Br. J. Obstet. Gynaecol. 1994; 1201: 709–10.CrossRefGoogle Scholar
15 Anon. Knowledge and use of folic acid by women of childbearing age — United States, 1997. Morbidity Mortality Weekly Rep. 1997; 46: 721–3.Google Scholar
16McGovern, E, Moss, H, Grewal, G, Taylor, A, Bjornsson, S, Pell, J. Factors affecting the use of folic acid supplements in pregnant women in Glasgow. Br. J. Gen. Pract. 1997; 47: 635–7.Google ScholarPubMed
17Kadir, RA, Sabin, C, Whitlow, B, Economides, D. Neural tube defects and periconceptional folic acid in England and Wales: retrospective study [with commentary by E Alberman and JM Noble]. Br. Med. J. 1999; 319: 92–3.Google Scholar
18Wald, NJ, Law, M, Jordan, R. Folic acid food fortification to prevent neural tube defects. Lancet 1998; 351: 834.CrossRefGoogle ScholarPubMed