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Schizophrenic syndromes, cognitive performance and neurological dysfunction

Published online by Cambridge University Press:  09 July 2009

Peter F. Liddle
Peter F. Liddle*
Affiliation:
Department of Psychiatry, University of Oxford
*
1Address for correspondence: Dr P. F. Liddle, Charing Cross and Westminster Medical School, Academic Unit, Horton Hospital, Long Grove Road, Epsom, Surrey KT9 8PZ.
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Synopsis

In a sample of chronic schizophrenic patients, a group of symptoms which included poverty of speech and lack of spontaneous movement was found to be associated with poor performance in tests of conceptual thinking, object naming and long-term memory, and also with cortical neurological signs. A second group of symptoms which included formal thought disorder and inappropriate affect was associated with poor performance in tests of concentration, immediate recall and word learning, and with cortical neurological signs. The findings suggest that these two syndromes are associated with dysfunction at two different sites within the frontal lobes. A third group of symptoms, comprising various delusions and hallucinations, was associated with poor figure-ground perception, and might reflect temporal lobe dysfunction.

Type
Research Article
Information
Psychological Medicine , Volume 17 , Issue 1 , February 1987 , pp. 49 - 57
Copyright
Copyright © Cambridge University Press 1987

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