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A multidimensional approach to impulsivity in Parkinson's disease: measurement and structural invariance of the UPPS Impulsive Behaviour Scale

Published online by Cambridge University Press:  27 July 2016

S. Bayard ,
E. Joly ,
P. Ghisletta ,
A. Rossignol ,
Y. Herades ,
C. Geny ,
M.-C. Gély-Nargeot  and
L. Rochat
S. Bayard*
Affiliation:
Laboratoire Epsylon, EA 4556, Universités Paul Valéry, Montpellier, France
E. Joly
Affiliation:
Methodology and Data Analysis Unit, University of Geneva, Geneva, Switzerland
P. Ghisletta
Affiliation:
Methodology and Data Analysis Unit, University of Geneva, Geneva, Switzerland Distance Learning University, Sierre, Switzerland
A. Rossignol
Affiliation:
Service de Neurologie, Hôpital Gui de Chauliac, Montpellier, France
Y. Herades
Affiliation:
Consultation mémoire, CH Val d'Ariège, Foix, France
C. Geny
Affiliation:
Service de Neurologie, Hôpital Gui de Chauliac, Montpellier, France
M.-C. Gély-Nargeot
Affiliation:
Laboratoire Epsylon, EA 4556, Universités Paul Valéry, Montpellier, France
L. Rochat
Affiliation:
Cognitive Psychopathology and Neuropsychology Unit, University of Geneva, Switzerland Swiss Centre for Affective Sciences, University of Geneva, Switzerland
*
*Address for correspondence: S. Bayard, PhD, MCU, Laboratoire Epsylon, EA 4556, Universités Montpellier, Rue du Pr. Henri Serre, 34000 Montpellier, France. (Email: [email protected])
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Abstract

Background

Poor impulse control is a common feature in patients with Parkinson's disease (PD). However, before testing whether patients with PD and controls differ in impulsivity, one must assess whether impulsivity measures are invariant across groups. Consequently, we examined (a) the measurement and structural invariance of a scale assessing changes in four dimensions of impulsivity (urgency, lack of premeditation, lack of perseverance and sensation seeking) among patients with PD and controls; and (b) whether the four impulsivity traits relate differentially to risky decisions by patients.

Method

Close relatives of 78 patients with idiopathic PD and 96 control participants were given the short Urgency–Premeditation–Perseverance–Sensation seeking Impulsive Behaviour Scale (UPPS), which assesses changes in four dimensions of impulsivity. Participants also completed the Game of Dice Task (GDT), a laboratory measure of risk taking.

Results

Multigroup confirmatory factor analyses supported measurement invariance across groups, whereas structural invariance was not confirmed. Patients with PD showed greater variability and higher impulsivity than controls. Furthermore, patients with impulse control disorders (ICDs) demonstrated even greater levels of sensation seeking than patients without ICDs. Finally, lower premeditation and greater perseverance were significantly associated with greater risk taking in patients with PD, and higher agonist dopaminergic doses with less risky choices on the GDT.

Conclusions

The questionnaire appears to function comparably across patients and controls. Thus, group comparisons on the questionnaire can be considered valid. Mean differences between groups on the dimensions of impulsivity may reflect executive impairments and/or abnormal reward processing in patients with PD, which may lead to risky behaviours.

Keywords

Impulsivityimpulse control disordersmeasurement invarianceParkinson's diseaserisk takingUPPS Impulsive Behaviour Scale
Type
Original Articles
Information
Psychological Medicine , Volume 46 , Issue 14 , October 2016 , pp. 2931 - 2941
Copyright
Copyright © Cambridge University Press 2016 

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