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Mental development of phenylketonuric children on or off diet after the age of six

Published online by Cambridge University Press:  09 July 2009

Eleanor S. Brown  and
Robert Warner
Eleanor S. Brown*
Affiliation:
Department of Pediatrics and the Waisman Center on Mental Retardation and Human Development, University of Wisconsin, Madison, and the Children's Rehabilitation Center, Children's Hospital, Buffalo, New York
Robert Warner
Affiliation:
Department of Pediatrics and the Waisman Center on Mental Retardation and Human Development, University of Wisconsin, Madison, and the Children's Rehabilitation Center, Children's Hospital, Buffalo, New York
*
1Address for correspondence: Eleanor S. Brown, Ph.D., Department of Pediatrics and Waisman Center on Mental Retardation and Human Development, University of Wisconsin, 2605 Marsh Lane, Madison, W1 53706.
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Synopsis

Eleven children with phenylketonuria (PKU) taken off diet after the age of six showed significant decreases in rate of mental development compared with 26 control children of comparable IQ and with 17 PKU children of comparable IQ who remained on the diet. Changes in rate of mental development were significantly and inversely correlated with plasma phenylalanine levels in treated PKU.

Type
Research Article
Information
Psychological Medicine , Volume 6 , Issue 2 , May 1976 , pp. 287 - 296
Copyright
Copyright © Cambridge University Press 1976

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References

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