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Genetic and environmental influences on anorexia nervosa syndromes in a population–based twin sample

Published online by Cambridge University Press:  17 May 2001

K. L. KLUMP ,
K. B. MILLER ,
P. K. KEEL ,
M. McGUE  and
W. G. IACONO
K. L. KLUMP
Affiliation:
From the Department of Psychology, Michigan State University, East Lansing, MI; Department of Psychology, University of Minnesota, Minneapolis, MN; and Department of Psychology, Harvard University, Boston, MA, USA
K. B. MILLER
Affiliation:
From the Department of Psychology, Michigan State University, East Lansing, MI; Department of Psychology, University of Minnesota, Minneapolis, MN; and Department of Psychology, Harvard University, Boston, MA, USA
P. K. KEEL
Affiliation:
From the Department of Psychology, Michigan State University, East Lansing, MI; Department of Psychology, University of Minnesota, Minneapolis, MN; and Department of Psychology, Harvard University, Boston, MA, USA
M. McGUE
Affiliation:
From the Department of Psychology, Michigan State University, East Lansing, MI; Department of Psychology, University of Minnesota, Minneapolis, MN; and Department of Psychology, Harvard University, Boston, MA, USA
W. G. IACONO
Affiliation:
From the Department of Psychology, Michigan State University, East Lansing, MI; Department of Psychology, University of Minnesota, Minneapolis, MN; and Department of Psychology, Harvard University, Boston, MA, USA
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Abstract

Background. Genetic and environmental influences on broadly-defined anorexia nervosa (AN) syndrome were examined in a population-based twin sample.

Methods. AN syndrome was assessed in 672 female 17 year-old twins using structured interviews and a self-report questionnaire.

Results. Twenty-six probands with AN syndrome were identified. Biometrical model-fitting analyses indicated that genetic and non-shared environmental factors accounted for 74 % and 26 % of the variance in AN syndrome, respectively.

Conclusions. Findings support previous research indicating significant genetic and non-shared environmental influences on AN syndromes.

Type
Brief Communication
Information
Psychological Medicine , Volume 31 , Issue 4 , May 2001 , pp. 737 - 740
Copyright
© 2001 Cambridge University Press

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