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Functioning status of adult children of depressed parents: a 23-year follow-up

Published online by Cambridge University Press:  08 November 2007

C. Timko*
Affiliation:
Center for Health Care Evaluation, Department of Veterans Affairs Health Care System, and Stanford University Medical Center, Palo Alto, California, USA
R. C. Cronkite
Affiliation:
Center for Health Care Evaluation, Department of Veterans Affairs Health Care System, and Stanford University Medical Center, Palo Alto, California, USA
R. Swindle
Affiliation:
Eli Lilly and Company, Indianapolis, Indiana, USA
R. L. Robinson
Affiliation:
Eli Lilly and Company, Indianapolis, Indiana, USA
P. Turrubiartes
Affiliation:
Center for Health Care Evaluation, Department of Veterans Affairs Health Care System, and Stanford University Medical Center, Palo Alto, California, USA
R. H. Moos
Affiliation:
Center for Health Care Evaluation, Department of Veterans Affairs Health Care System, and Stanford University Medical Center, Palo Alto, California, USA
*
*Address for correspondence: C. Timko, Ph.D., Center for Health Care Evaluation, VA Health Care System(152-MPD), 795 Willow Road, Menlo Park, CA 94025, USA. (Email: [email protected])

Abstract

Background

We compared adult offspring of depressed or control parents who were followed for 23 years. Comparisons were on depression symptoms, physical functioning and disability, social functioning, and utilization of help and coping. Also examined was whether the parent's course of depression (stably remitted, partially remitted, non-remitted) was associated with offspring functioning.

Method

Depressed parents successfully followed at 23 years (n=248, 82%) identified 215 adult offspring; 67% returned questionnaires. Matched control parents successfully followed (n=235, 79%) identified 261 adult offspring; 68% completed questionnaires.

Results

Adult offspring of depressed parents were more impaired than adult offspring of controls (with gender and education controlled) in the domains of depression and disability, and obtained more help for mental health problems. They also reported more severe recent stressors and relied more on active cognitive coping and seeking alternative rewards to cope. Adult offspring of depressed and control parents were comparable in a number of domains: psychiatric and behavioral problems other than depression, physical functioning and pain, social functioning, and hospitalizations and medication use for depression. Adult offspring of parents with a non-remitted course of depression were the most likely to show impaired functioning compared with controls.

Conclusions

Having a parent with depression is associated with more depression and disability in adulthood, but does not have debilitating effects in other life domains. Nonetheless, it may be important for offspring of depressed parents, particularly offspring of parents with a non-remitting depression course, to recognize their elevated risk of depression and potential need for help.

Type
Original Articles
Copyright
Copyright © Cambridge University Press 2007

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Footnotes

This paper was presented in part at the annual meetings of the American Psychiatric Association, Toronto, Canada, 23 May 2006, and of the Institute of Psychiatric Services, New York, 5 October 2006.

References

Adler, DA, McLaughlin, TJ, Rogers, WH, Chang, H, Lapitsky, L, Lerner, D (2006). Job performance deficits due to depression. American Journal of Psychiatry 163, 14901491.CrossRefGoogle ScholarPubMed
Adrian, C, Hammen, C (1993). Stress exposure and stress generation in children of depressed mothers. Journal of Consulting and Clinical Psychology 61, 354359.CrossRefGoogle ScholarPubMed
Arnow, BA, Hunkeler, EM, Blasey, CM, Lee, J, Constantino, MJ, Fireman, B, Kraemer, HC, Dea, R, Robinson, R, Hayward, C (2006). Comorbid depression, chronic pain, and disability in primary care. Psychosomatic Medicine 68, 262268.CrossRefGoogle ScholarPubMed
Barney, LJ, Griffiths, KM, Jorm, AF, Christensen, H (2006). Stigma about depression and its impact on help-seeking intentions. The Australian and New Zealand Journal of Psychiatry 40, 5154.CrossRefGoogle ScholarPubMed
Beardslee, WR (2002). Out of the Darkened Room. Little Brown: Boston, MD.Google Scholar
Billings, AG, Moos, RH (1984). Treatment experiences of adults with unipolar depression: the influence of patient and life context factors. Journal of Consulting and Clinical Psychology 52, 119131.CrossRefGoogle ScholarPubMed
Breslin, FC, Gnam, W, Franche, RL, Mustard, C, Lin, E (2006). Depression and activity limitations: examining gender differences in the general population. Social Psychiatry and Psychiatric Epidemiology 23, 648655.CrossRefGoogle Scholar
Cronkite, RC, Swindle, R, Robinson, LL, Moos, RH (2006). Course of depression over 23 years. Center for Health Care Evaluation: Palo Alto, CA.Google Scholar
Cummings, EM, Davies, PT (1994). Maternal depression and child development. Journal of Child Psychology and Psychiatry 35, 73112.CrossRefGoogle ScholarPubMed
Downey, G, Coyne, JC (1990). Children of depressed parents: an integrative review. Psychological Bulletin 108, 5076.Google Scholar
Ensminger, ME, Hanson, SG, Riley, AW, Juon, H (2003). Maternal psychological distress: adult sons' and daughters' mental health and educational attainment. Journal of the American Academy of Child & Adolescent Psychiatry 42, 11081115.CrossRefGoogle ScholarPubMed
Forehand, R, Biggar, H, Kotchick, BA (1998). Cumulative risk factors across family stressors. Journal of Abnormal Child Psychology 26, 119128.Google Scholar
Goodman, SH, Gotlib, IH (2002). Children of depressed parents. American Psychological Association: Washington, DC.Google Scholar
Holahan, CJ, Moos, RH (1991). Life stressors, personal and social resources, and depression: a 4-year structural model. Journal of Abnormal Psychology 100, 3138.CrossRefGoogle ScholarPubMed
Holahan, CJ, Moos, RH, Holahan, CK, Brennan, PL, Schutte, KK (2005). Stress generation, avoidance coping, and depressive symptoms: a 10-year model. Journal of Consulting and Clinical Psychology 73, 658666.CrossRefGoogle ScholarPubMed
Holahan, CJ, Moos, RH, Holahan, CK, Cronkite, RC (1999). Resource loss, resource gain, and depressive symptoms: a 10-year model. Journal of Personality and Social Psychology 77, 620629.CrossRefGoogle ScholarPubMed
Holmes, TH, Rahe, RH (1967). The Social Readjustment Rating Scale. Journal of Psychosomatic Research 11, 213218.CrossRefGoogle ScholarPubMed
Jaser, SS, Langrock, AM, Keller, G, Merchant, MJ, Benson, MA, Reeslund, K, Champion, JE, Compas, BE (2005). Coping with the stress of parental depression II: adolescent and parent reports of coping and adjustment. Journal of Clinical Child and Adolescent Psychology 34, 193205.Google Scholar
Johnson, JG, Cohen, P, Kasen, S, Smailes, E, Brook, JS (2001). Association of maladaptive parental behavior with psychiatric disorder among parents and their offspring. Archives of General Psychiatry 58, 453460.Google Scholar
Kahn, A, Brodhead, AE, Schwartz, KA, Kolts, RL, Brown, WA (2005). Sex differences in antidepressant response in recent antidepressant clinical trials. Journal of Clinical Psychopharmacology 25, 318324.Google Scholar
Keller, MB, Beardslee, WR, Dorer, DJ, Lavori, PW, Samuelson, H, Klerman, GR (1986). Impact of severity and chronicity of parental affective illness on adaptive functioning and psychopathology in children. Archives of General Psychiatry 43, 930937.Google Scholar
Kendler, KS (1995). Genetic epidemiology in psychiatry. Archives of General Psychiatry 52, 895899.Google Scholar
Kroenke, K, Spitzer, RL, Williams, JB (2001). The PHQ-9: validity of a brief depression severity measure. Journal of General Internal Medicine 16, 606613.CrossRefGoogle ScholarPubMed
Langrock, AM, Compas, BE, Keller, G, Merchant, MJ, Copeland, ME (2002). Coping with the stress of parental depression: parents' reports of children's coping, emotional, and behavioral problems. Journal of Clinical Child and Adolescent Psychology 31, 312324.CrossRefGoogle ScholarPubMed
Lieb, R, Isensee, B, Hofler, M, Pfister, H, Wittchen, H (2002). Parental major depression and the risk of depression and other mental disorders in offspring: a prospective-longitudinal community study. Archives of General Psychiatry 59, 365374.CrossRefGoogle ScholarPubMed
Lyubomirsky, S, King, L, Diener, E (2005). The benefits of frequent positive affect. Psychological Bulletin 131, 803855.CrossRefGoogle ScholarPubMed
Matheson, K, Anisman, H (2003). Systems of coping associated with dysphoria, anxiety and depressive illness: a multivariate profile perspective. Stress 6, 223234.CrossRefGoogle ScholarPubMed
Moos, RH (1993). Coping responses inventory: adult form manual. Psychological Assessment Resources: Odessa, FL.Google Scholar
Moos, RH (1994). Work Environment Scale Manual, 3rd edn. Consulting Psychologists Press: Palo Alto, CA.Google Scholar
Moos, RH, Cronkite, RC, Finney, JW (1992). Health and Daily Living Form Manual, 2nd edn. Mind Garden: Menlo Park, CA.Google Scholar
Moos, RH, Cronkite, RC, Moos, BS (1998). Family and extrafamily resources and the 10-year course of treated depression. Journal of Abnormal Psychology 107, 450460.CrossRefGoogle ScholarPubMed
Moos, RH, Moos, BS (1994). Family Environment Scale Manual, 3rd edn. Mind Garden: Menlo Park, CA.Google Scholar
Peisah, C, Brodaty, H, Luscombe, G, Anstey, KJ (2004). Children of a cohort of depressed patients 25 years later: psychopathology and relationships. Journal of Affective Disorders 82, 385394.Google Scholar
Radke-Yarrow, M (1998). Children of depressed mothers. Cambridge University Press: Cambridge, UK.Google Scholar
Ravindran, AV, Matheson, K, Griffiths, J, Merali, Z, Anisman, H (2002). Stress, coping, uplifts, and quality of life in subtypes of depression: a conceptual frame and emerging data. Journal of Affective Disorders 71, 121130.Google Scholar
Rende, RD, Plomin, R, Reiss, D, Hetherington, EM (1993). Genetic and environmental influences on depressive symptomatology in adolescence. Journal of Child Psychology and Psychiatry 34, 13871398.Google Scholar
Rudisch, B, Nemeroff, CB (2003). Epidemiology of comorbid coronary artery disease and depression. Biological Psychiatry 54, 227240.Google Scholar
Rutter, M (1990). Some focus and process considerations regarding effects of parental depression on children. Developmental Psychology 26, 6067.Google Scholar
Sanderson, K, Andrews, G (2006). Common mental disorders in the workforce: recent findings from descriptive and social epidemiology. Canadian Journal of Psychiatry 51, 6162.Google Scholar
Spitzer, RL, Endicott, J, Robins, E (1978). Research diagnostic criteria: rationale and reliability. Archives of General Psychiatry 35, 773782.Google Scholar
Staw, BM, Sutton, R, Pelled, LH (1994). Employee positive emotion and favorable outcomes at the workplace. Organizational Science 5, 5171.CrossRefGoogle Scholar
Swindle, RW, Cronkite, RC, Moos, RH (1989). Life stressors, social resources, coping, and the 4-year course of unipolar depression. Journal of Abnormal Psychology 98, 468477.Google Scholar
Timko, C, Cronkite, RC, Berg, E, Moos, RH (2002). Children of parents with unipolar depression: a comparison of stably remitted, partially remitted, and nonremitted parents and nondepressed controls. Child Psychiatry and Human Development 32, 165185.CrossRefGoogle ScholarPubMed
Von Korff, M, Ormel, J, Keefe, FJ, Dworkin, SF (1992). Grading the severity of chronic pain. Pain 50, 133149.Google Scholar
Weissman, MM, Pilowsky, DJ, Wickramaratne, PJ, Talati, A, Wisniewski, S, Fava, M, Hughes, CW, Garber, J, Malloy, E, King, CA, Cerda, G, Sood, AB, Alpert, JE, Trivedi, MH, Rush, AJ (2006 b). Remissions in maternal depression and child psychopathology. Journal of the American Medical Association 295, 13891398.Google Scholar
Weissman, MM, Warner, V, Wickramaratne, P, Moreau, D, Olfson, M (1997). Offspring of depressed parents: 10 years later. Archives of General Psychiatry 54, 932940.Google Scholar
Weissman, MM, Wickramaratne, P, Nomura, Y, Warner, V, Pilowsky, D, Verdeli, H (2006 a). Offspring of depressed parents: 20 years later. American Journal of Psychiatry 163, 10011008.Google Scholar
Weisz, JR, McCabe, M, Denning, MD (1994). Primary and secondary control among children undergoing medical procedures. Journal of Consulting and Clinical Psychology 62, 324332.Google Scholar
Williams, OB, Corrigan, PW (1992). The differential effects of parental alcoholism and mental illness on their adult children. Journal of Clinical Psychology 48, 406414.3.0.CO;2-L>CrossRefGoogle ScholarPubMed