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Family-focused cognitive behaviour therapy versus psycho-education for chronic fatigue syndrome in 11- to 18-year-olds: a randomized controlled treatment trial

Published online by Cambridge University Press:  06 November 2009

T. Chalder*
Affiliation:
Department of Psychological Medicine and Psychiatry, King's College London, Weston Education Centre, London, UK
V. Deary
Affiliation:
Institute of Health and Society, Newcastle University, Newcastle, UK
K. Husain
Affiliation:
Psychology Department, Central and North West London NHS Foundation Trust, Northwick Park Hospital, Harrow, UK
R. Walwyn
Affiliation:
Mental Health and Neuroscience Clinical Trials Unit, Institute of Psychiatry, King's College London, London, UK
*
*Address for correspondence: Professor T. Chalder, Department of Psychological Medicine and Psychiatry, King's College London, Weston Education Centre, Cutcombe Road, London SE5 9RJ, UK. (Email: [email protected])

Abstract

Background

Only one previous randomized controlled trial (RCT) has examined the efficacy of cognitive behaviour therapy (CBT) for chronic fatigue syndrome (CFS) in children. The aim of this study was to compare family-focused CBT with psycho-education for CFS in adolescents.

Method

Sixty-three 11- to 18-year-olds (43 girls, 20 boys) with CFS were randomly assigned to either family-focused CBT or psycho-education delivered over 6 months. School attendance was the main outcome, which was assessed at the end of treatment and at 3, 6 and 12 months follow-up.

Results

At the main outcome point (the 6-month follow-up) both groups had improved similarly. However, although those who received family-focused CBT were attending school for longer than those who received psycho-education, at discharge from treatment and at 3 months follow-up, they improved less quickly across the follow-up period.

Conclusions

Adolescents with CFS get back to school more quickly after family-focused CBT. This is important as they are at a crucial stage of their development. However, the finding that psycho-education was as effective as family-focused CBT at 6 and 12 months follow-up has important implications for health service delivery.

Type
Original Articles
Copyright
Copyright © Cambridge University Press 2009

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References

Bell, DS, Jordan, K, Robinson, M (2001). Thirteen-year follow-up of children and adolescents with chronic fatigue syndrome. Pediatrics 107, 994998.Google ScholarPubMed
Chalder, T (1999). Family oriented cognitive behavioural treatment for adolescents with chronic fatigue syndrome. Association of Child Psychology and Psychiatry Occasional Papers 16, 1923.Google Scholar
Chalder, T (2005). Chronic fatigue syndrome. In Cognitive Behaviour Therapy for Children and Families, 2nd edn (ed. Graham, P.), pp. 385401. Cambridge University Press: Cambridge.Google Scholar
Chalder, T, Berelowitz, G, Pawlikowska, T, Watts, L, Wessely, S, Wright, D, Wallace, EP (1993). Development of a fatigue scale. Journal of Psychosomatic Research 37, 147153.CrossRefGoogle ScholarPubMed
Chalder, T, Husain, K (2002). Self Help for Chronic Fatigue Syndrome: A guide for young people. Blue Stallion Publication: Witney, Oxon.Google Scholar
Chalder, T, Tong, J, Deary, V (2002). Family focused cognitive behaviour therapy for chronic fatigue syndrome in adolescents. Archives of Disease in Children 86, 9597.CrossRefGoogle Scholar
Deale, A, Chalder, T, Marks, I, Wessely, S (1997). A randomised controlled trial of cognitive behaviour versus relaxation therapy for chronic fatigue syndrome. American Journal of Psychiatry 154, 408414.Google Scholar
Fukuda, K, Straus, S, Hickie, I, Sharpe, M, Dobbins, J, Komaroff, A (1994). The chronic fatigue syndrome: a comprehensive approach to its definition and study. Annals of Internal Medicine 12, 953959.CrossRefGoogle Scholar
Goodman, R (1997). The Strengths and Difficulties Questionnaire: a research note. Journal of Child Psychology and Psychiatry 38, 581586.CrossRefGoogle ScholarPubMed
Joyce, J, Hotopf, M, Wessely, SC (1997). The prognosis of chronic fatigue and chronic fatigue syndrome. Quarterly Journal of Medicine 90, 223233.CrossRefGoogle ScholarPubMed
Knoop, H, Stulemeijer, M, de Jong, LWAM, Fiselier, TJW, Bleijenberg, G (2008). Efficacy of cognitive behavioral therapy for adolescents with chronic fatigue syndrome: long-term follow-up of a randomized, controlled trial. Pediatrics 121, e619e625.CrossRefGoogle ScholarPubMed
Mundt, JC, Marks, IM, Shear, K, Griest, JH (2002). The Work and Social Adjustment Scale: a simple measure of impairment in functioning. British Journal of Psychiatry 180, 461464.CrossRefGoogle Scholar
Prins, JB, Bleijenberg, G, Bazelmans, E, Elving, LD, de Boo, TM, Severens, JL, van der Wilt, GJ, Spinhoven, P, van der Meer, JWM (2001). Cognitive behaviour therapy for chronic fatigue syndrome: a multicentre randomised controlled trial. Lancet 357, 841847.CrossRefGoogle ScholarPubMed
Rangel, L, Garralda, ME, Levin, M, Roberts, H (2000). The course of severe fatigue syndrome in childhood. Journal of the Royal Society of Medicine 93, 129134.CrossRefGoogle ScholarPubMed
Sankey, A, Hill, CM, Brown, J, Quinn, L, Fletcher, A (2006). A follow-up study of chronic fatigue syndrome in children and adolescents: symptom persistence and school absenteeism. Child Psychology and Psychiatry 11, 126138.CrossRefGoogle ScholarPubMed
Sharpe, MC, Archard, LC, Banatvala, JE, Borysiewicz, LK, Clare, AW, David, A, Edwards, RHT, Hawton, KEH, Lambert, HP, Lane, RJM, McDonald, EM, Mowbray, JF, Pearson, DJ, Peto, TEA, Preedy, VR, Smith, AP, Smith, DG, Taylor, DJ, Tyrrell, DAJ, Wessely, S, White, PD (1991). A report – chronic fatigue syndrome: guidelines for research. Journal of the Royal Society of Medicine 84, 118121.CrossRefGoogle ScholarPubMed
Sharpe, M, Hawton, K, Simkin, S, Surawy, C, Hackmann, A, Klimas, I, Peto, T, Warrell, D, Seagrott, V (1996). Cognitive behaviour therapy for the chronic fatigue syndrome: a randomised controlled trial. British Medical Journal 312, 2226.CrossRefGoogle Scholar
Stewart, AL, Hays, RD, Ware, JE Jr. (1988). The MOS short-form general health survey: reliability and validity in a patient population. Medical Care 26, 724732.CrossRefGoogle Scholar
Stulemeijer, M, de Jong, LWAM, Fiselier, TJW, Hoogveld, SWB, Bleijenberg, G (2005). Cognitive behaviour therapy for adolescents with chronic fatigue syndrome: randomised controlled trial. British Medical Journal 330, 14.CrossRefGoogle ScholarPubMed
van de Putte, EM, van Doornen, LJP, Engelbert, RHH, Wietse Kuis, PT, Kimpen, JLL, Uiterwaal, CSPM (2006). Mirrored symptoms in mother and child with chronic fatigue syndrome. Paediatrics 117, 20742079.CrossRefGoogle ScholarPubMed