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(Des-Tyr1)-γ-endorphin in the treatment of schizophrenia

Published online by Cambridge University Press:  09 July 2009

Rahul Manchanda  and
Steven R. Hirsch
Rahul Manchanda
Affiliation:
Department of Psychiatry, Charing Cross Hospital Medical School, London
Steven R. Hirsch*
Affiliation:
Department of Psychiatry, Charing Cross Hospital Medical School, London
*
1Address for correspondence: Professor S. R. Hirsch, Department of Psychiatry, Charing Cross Hospital Medical School, Fulham Palace Road, London W6 8RF.
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Synopsis

Inj. (Des-Tyr1)-γ-endorphin was used in a pilot study over a period of 12 days for the treatment of 11 schizophrenics and the assessments were carried out using standardized rating scales. Only 2 patients showed an improvement. Euphoria and excitement were observed in 3 patients. The findings are discussed in contrast to the earlier reports of a dramatic improvement with the compound.

Type
Brief Communication
Information
Psychological Medicine , Volume 11 , Issue 2 , May 1981 , pp. 401 - 404
Copyright
Copyright © Cambridge University Press 1981

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