Hostname: page-component-cd9895bd7-jkksz Total loading time: 0 Render date: 2024-12-26T13:08:12.205Z Has data issue: false hasContentIssue false

Depression is both psychosocial and biological; antidepressants are both effective and in need of improvement; psychiatrists are both caring human beings and doctors who prescribe medications. Can we all agree on this? a commentary on ‘Read & Moncrieff – depression: why drugs and electricity are not the answer’

Published online by Cambridge University Press:  01 April 2022

Carmine M. Pariante*
Affiliation:
Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK
*
Author for correspondence: Carmine M. Pariante, E-mail: [email protected]

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Invited Commentary
Copyright
Copyright © The Author(s), 2022. Published by Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Espinoza, R.T., & Kellner, C.H. (2022). Electroconvulsive therapy. New England Journal of Medicine, 386, 667672. doi: 10.1056/NEJMra2034954CrossRefGoogle ScholarPubMed
Hamilton, M. (1960). A rating scale for depression. Journal of Neurology, Neurosurgery and Psychiatry, 23, 5662. Retrieved from https://doi.org/10.1136/jnnp.23.1.56.CrossRefGoogle ScholarPubMed
Hieronymus, F., Emilsson, J.F., Nilsson, S., & Eriksson, E. (2016). Consistent superiority of selective serotonin reuptake inhibitors over placebo in reducing depressed mood in patients with major depression. Molecular Psychiatry, 21, 523530. doi: 10.1038/mp.2015.53CrossRefGoogle ScholarPubMed
Hieronymus, F., Jauhar, S., Østergaard, S.D., & Young, A.H. (2020). One (effect) size does not fit at all: Interpreting clinical significance and effect sizes in depression treatment trials. Journal of Psychopharmacology, 34,10741078. doi: 10.1177/0269881120922950CrossRefGoogle Scholar
Hieronymus, F., Lisinski, A., Nilsson, S., & Eriksson, E. (2018). Efficacy of selective serotonin reuptake inhibitors in the absence of side effects: A mega-analysis of citalopram and paroxetine in adult depression. Molecular Psychiatry, 23, 17311736. doi: 10.1038/mp.2017.147CrossRefGoogle ScholarPubMed
Leucht, S., Hierl, S., Kissling, W., Dold, M., & Davis, J.M. (2012). Putting the efficacy of psychiatric and general medicine medication into perspective: Review of meta-analyses. British Journal of Psychiatry, 200, 97106. doi:10.1192/bjp.bp.111.096594CrossRefGoogle ScholarPubMed
Otte, C., Gold, S.M., Penninx, B.W., Pariante, C.M., Etkin, A., Fava, M., Mohr, D.C., … Schatzberg, A.F. (2016). Major depressive disorder. Nature Reviews Disease Primers, 2, 16065. doi: 10.1038/nrdp.2016.65CrossRefGoogle ScholarPubMed
Pariante, C.M. (2016). Neuroscience, mental health and the immune system: Overcoming the brain-mind-body trichotomy. Epidemiology and Psychiatric Sciences, 25(2), 101105. doi: 10.1017/S204579601500089XCrossRefGoogle ScholarPubMed
Pariante, C.M. (2019). Every Pregnancy is Everyone's Business. Inspire The Mind. Retrieved from https://www.inspirethemind.org/blog/2019/05/01/every-pregnancy-is-everyones-business.Google Scholar
Pariante, C.M. (2020). Letting children go hungry makes no economic (or moral) sense: so why do some governments try to do it? Inspire The Mind. Retrieved from https://www.inspirethemind.org/blog/letting-children-go-hungry-makes-no-economic-or-moral-sense.Google Scholar
Pariante, C.M. (2021). The London Riots, a Psychiatrist's Perspective. Inspire The Mind. Retrieved from https://www.inspirethemind.org/blog/the-london-riots-a-psychiatrists-perspective.Google Scholar
Read, J., & Moncrieff, J. (2022) Depression: Why drugs and electricity are not the answer. Psychological Medicine, 1, 110. doi: 10.1017/S0033291721005031CrossRefGoogle Scholar
Royal College of Psychiatrists, UK (2019). Position statement on antidepressants and depression. Retrieved from https://www.rcpsych.ac.uk/docs/default-source/improving-care/better-mh-policy/position-statements/ps04_19---antidepressants-and-depression.pdf.Google Scholar
Sforzini, L., Worrell, C., Kose, M., Anderson, I.M., Aouizerate, B., Arolt, V., … Pariante, C.M. (2021). A Delphi-method-based consensus guideline for definition of treatment-resistant depression for clinical trials. Molecular Psychiatry, Dec 15. doi: 10.1038/s41380-021-01381-xGoogle ScholarPubMed