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Defining the cognitive impairment in schizophrenia

Published online by Cambridge University Press:  21 October 2004

EILEEN JOYCE
Affiliation:
Division of Neuroscience and Mental Health, Imperial College Faculty of Medicine, St Dunstan's Road, London, UK
VYV HUDDY
Affiliation:
Division of Neuroscience and Mental Health, Imperial College Faculty of Medicine, St Dunstan's Road, London, UK

Extract

Cognitive psychology became an important discipline in schizophrenia research when information processing deficits were implicated as the basis from which psychotic symptoms emerged (Broen & Storms, 1967; Hemsley, 1977; Frith, 1979). The study of cognition as an independent construct began in earnest when the detection of brain morphological abnormalities on computed tomography (CT) in patients with schizophrenia (Johnstone et al. 1976; Weinberger et al. 1979) prompted the search for behavioural correlates. It became apparent that impairments typical of damage to frontal or medial temporal lobes could be seen in patients with schizophrenia, irrespective of symptom type or severity (Goldberg et al. 1988; McKenna et al. 1990). Since then a number of findings have been replicated sufficiently to make certain conclusions about the nature and extent of cognitive dysfunction in this disorder.

Type
Invited Review
Copyright
© 2004 Cambridge University Press

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