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Can delay discounting deliver on the promise of RDoC?

Published online by Cambridge University Press:  02 August 2018

Karolina M. Lempert ,
Joanna E. Steinglass ,
Anthony Pinto ,
Joseph W. Kable  and
Helen Blair Simpson
Karolina M. Lempert
Affiliation:
Department of Psychology, University of Pennsylvania, Philadelphia, PA, USA
Joanna E. Steinglass
Affiliation:
Department of Psychiatry, Columbia University Medical Center, New York, NY, USA New York State Psychiatric Institute, New York, NY, USA
Anthony Pinto
Affiliation:
Department of Psychiatry, Columbia University Medical Center, New York, NY, USA Division of Psychiatry Research, Zucker Hillside Hospital, Northwell Health System, Glen Oaks, NY, USA Department of Psychiatry, Hofstra Northwell School of Medicine, Hempstead, NY, USA
Joseph W. Kable
Affiliation:
Department of Psychology, University of Pennsylvania, Philadelphia, PA, USA
Helen Blair Simpson*
Affiliation:
Department of Psychiatry, Columbia University Medical Center, New York, NY, USA New York State Psychiatric Institute, New York, NY, USA
*
Author for correspondence: Blair H. Simpson, E-mail: [email protected]
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Abstract

The National Institute of Mental Health launched the Research Domain Criteria (RDoC) initiative to better understand dimensions of behavior and identify targets for treatment. Examining dimensions across psychiatric illnesses has proven challenging, as reliable behavioral paradigms that are known to engage specific neural circuits and translate across diagnostic populations are scarce. Delay discounting paradigms seem to be an exception: they are useful for understanding links between neural systems and behavior in healthy individuals, with potential for assessing how these mechanisms go awry in psychiatric illnesses. This article reviews relevant literature on delay discounting (or the rate at which the value of a reward decreases as the delay to receipt increases) in humans, including methods for examining it, its putative neural mechanisms, and its application in psychiatric research. There exist rigorous and reproducible paradigms to evaluate delay discounting, standard methods for calculating discount rate, and known neural systems probed by these paradigms. Abnormalities in discounting have been associated with psychopathology ranging from addiction (with steep discount rates indicating relative preference for immediate rewards) to anorexia nervosa (with shallow discount rates indicating preference for future rewards). The latest research suggests that delay discounting can be manipulated in the laboratory. Extensively studied in cognitive neuroscience, delay discounting assesses a dimension of behavior that is important for decision-making and is linked to neural substrates and to psychopathology. The question now is whether manipulating delay discounting can yield clinically significant changes in behavior that promote health. If so, then delay discounting could deliver on the RDoC promise.

Keywords

Cognitive neurosciencedecision-makingdelay discountingimpulsivityintertemporal choiceRDoC
Type
Review Article
Information
Psychological Medicine , Volume 49 , Issue 2 , January 2019 , pp. 190 - 199
Copyright
Copyright © Cambridge University Press 2018 

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Footnotes

*

Karolina M. Lempert and Joanna E. Steinglass contributed equally to this work.

References

Addis, DR, Pan, L, Vu, M-A, Laiser, N and Schacter, DL (2009) Constructive episodic simulation of the future and the past: distinct subsystems of a core brain network mediate imagining and remembering. Neuropsychologia 47, 2222–2238.Google Scholar
Amlung, M, Vedelago, L, Acker, J, Balodis, I and MacKillop, J (2017) Steep delay discounting and addictive behavior: a meta-analysis of continuous associations. Addiction 112, 51–62.Google Scholar
Andreoni, J and Sprenger, C (2012) Risk preferences are not time preferences. American Economic Review 102, 3357–3376.Google Scholar
Anokhin, AP, Golosheykin, S, Grant, JD and Heath, AC (2011) Heritability of delay discounting in adolescence: a longitudinal twin study. Behavior Genetics 41, 175–183.Google Scholar
Anokhin, AP, Grant, JD, Mulligan, RC and Heath, AC (2014) The genetics of impulsivity: evidence for the heritability of delay discounting. Biological Psychiatry 77, 887–894.Google Scholar
Audrain-McGovern, J, Rodriguez, D, Epstein, LH, Cuevas, J, Rodgers, K and Wileyto, EP (2009) Does delay discounting play an etiological role in smoking or is it a consequence of smoking? Drug and Alcohol Dependence 103, 99–106.Google Scholar
Avsar, KB, Weller, RE, Cox, JE, Reid, MA, White, DM and Lahti, AC (2013) An fMRI investigation of delay discounting in patients with schizophrenia. Brain and Behavior 3, 384–401.Google Scholar
Barker, V, Romaniuk, L, Cardinal, RN, Pope, M, Nicol, K and Hall, J (2015) Impulsivity in borderline personality disorder. Psychological Medicine 45, 1955–1964.Google Scholar
Bartels, DM and Urminsky, O (2015) To know and to care: how awareness and valuation of the future jointly shape consumer spending. Journal of Consumer Research 41, 1469–1485.Google Scholar
Bartholdy, S, Rennalls, S, Danby, H, Jacques, C, Campbell, IC, Schmidt, U and O'Daly, OG (2017) Temporal discounting and the tendency to delay gratification across the eating disorder spectrum. European Eating Disorders Review 25, 344–350.Google Scholar
Bartra, O, McGuire, JT and Kable, JW (2013) The valuation system: a coordinate-based meta-analysis of BOLD fMRI experiments examining neural correlates of subjective value. NeuroImage 76, 412–427.Google Scholar
Benoit, RG, Gilbert, SJ and Burgess, PW (2011) A neural mechanism mediating the impact of episodic prospection on farsighted decisions. The Journal of Neuroscience 31, 6771–6779.Google Scholar
Bickel, WK (2015) Discounting of delayed rewards as an endophenotype. Biological Psychiatry 77, 846–847.Google Scholar
Bickel, WK, Jarmolowicz, DP, Mueller, ET, Koffarnus, MN and Gatchalian, KM (2012) Excessive discounting of delayed reinforcers as a trans-disease process contributing to addiction and other disease-related vulnerabilities: emerging evidence. Pharmacology & Therapeutics 134, 287–297.Google Scholar
Bickel, WK, Wilson, AG, Chen, C, Koffarnus, MN and Franck, CT (2016) Stuck in time: negative income shock constricts the temporal window of valuation spanning the future and the past. PLoS ONE 11, e0163051.Google Scholar
Bickel, WK, Yi, R, Kowal, BP and Gatchalian, KM (2008) Cigarette smokers discount past and future rewards symmetrically and more than controls: is discounting a measure of impulsivity? Drug and Alcohol Dependence 96, 256–262.Google Scholar
Blanchard, TC and Hayden, BY (2015) Monkeys are more patient in a foraging task than in a standard intertemporal choice task. PLoS ONE 10, e0117057.Google Scholar
Burrow, AL and Spreng, RN (2016) Waiting with purpose: a reliable but small association between purpose in life and impulsivity. Personality and Individual Differences 90, 187–189.Google Scholar
Camille, N, Griffiths, CA, Vo, K, Fellows, LK and Kable, JW (2011) Ventromedial frontal lobe damage disrupts value maximization in humans. Journal of Neuroscience 31, 7527–7532.Google Scholar
Carlisi, CO, Norman, L, Murphy, CM, Christakou, A, Chantiluke, K, Giampietro, V, Simmons, A, Brammer, M, Murphy, DG, Mataix-Cols, D, Rubia, K and Rubia, K (2017) Comparison of neural substrates of temporal discounting between youth with autism spectrum disorder and with obsessive-compulsive disorder. Psychological Medicine 47, 2513–2527.Google Scholar
Chesson, HW, Leichliter, JS, Zimet, GD, Rosenthal, SL, Bernstein, DI and Fife, KH (2006) Discount rates and risky sexual behaviors among teenagers and young adults. Journal of Risk and Uncertainty 32, 217–230.Google Scholar
Cools, R, Nakamura, K and Daw, ND (2011) Serotonin and dopamine: unifying affective, activational, and decision functions. Neuropsychopharmacology 36, 98–113.Google Scholar
Decker, JH, Figner, B and Steinglass, JE (2015) On weight and waiting: delay discounting in anorexia nervosa pretreatment and posttreatment. Biological Psychiatry 78, 606–614.Google Scholar
de Wit, H, Enggasser, JL and Richards, JB (2002) Acute administration of d-amphetamine decreases impulsivity in healthy volunteers. Neuropsychopharmacology 27, 813–825.Google Scholar
de Wit, H, Flory, JD, Acheson, A, McCloskey, M and Manuck, SB (2007) IQ and nonplanning impulsivity are independently associated with delay discounting in middle-aged adults. Personality and Individual Differences 42, 111–121.Google Scholar
Dom, G, De Wilde, B, Hulstijn, W, van den Brink, W and Sabbe, B (2006) Decision-making deficits in alcohol-dependent patients with and without comorbid personality disorder. Alcoholism, Clinical and Experimental Research 30, 1670–1677.Google Scholar
Dombrovski, AY, Szanto, K, Siegle, GJ, Wallace, ML, Forman, SD, Sahakian, B, Reynolds, CF and Clark, L (2011) Lethal forethought: delayed reward discounting differentiates high- and low-lethality suicide attempts in old age. Biological Psychiatry 70, 138–144.Google Scholar
Doya, K (2002) Metalearning and neuromodulation. Neural Networks 15, 495–506.Google Scholar
Doyle, JR (2013) Survey of time preference, delay discounting models. Judgment and Decision Making 8, 116–135.Google Scholar
Duckworth, AL and Kern, ML (2011) A meta-analysis of the convergent validity of self-control measures. Journal of Research in Personality 45, 259–268.Google Scholar
Figner, B, Knoch, D, Johnson, EJ, Krosch, AR, Lisanby, SH, Fehr, E and Weber, EU (2010) Lateral prefrontal cortex and self-control in intertemporal choice. Nature Neuroscience 13, 538–539.Google Scholar
Foerde, K, Figner, B, Doll, BB, Woyke, IC, Braun, EK, Weber, EU and Shohamy, D (2016) Dopamine modulation of intertemporal decision-making: evidence from Parkinson disease. Journal of Cognitive Neuroscience 28, 657–667.Google Scholar
Gordon, J (2017) The Future of RDoC. Published Online 5 June 2017. Available at https://www.nimh.nih.gov/about/director/messages/2017/the-future-of-rdoc.shtml.Google Scholar
Green, L and Myerson, J (2004) A discounting framework for choice with delayed and probabilistic rewards. Psychological Bulletin 130, 769–792.Google Scholar
Green, L, Myerson, J, Lichtman, D, Rosen, S and Fry, A (1996) Temporal discounting in choice between delayed rewards: the role of age and income. Psychology and Aging 11, 79–84.Google Scholar
Green, L, Myerson, J and McFadden, E (1997) Rate of temporal discounting decreases with amount of reward. Memory & Cognition 25, 715–723.Google Scholar
Halfmann, K, Hedgcock, W, Kable, J and Denburg, NL (2015) Individual differences in the neural signature of subjective value among older adults. Social Cognitive and Affective Neuroscience 11, 1111–1120.Google Scholar
Hardisty, DJ, Thompson, KF, Krantz, DH and Weber, EU (2013) How to measure time preferences: an experimental comparison of three methods. Judgment and Decision Making 22, 479–489.Google Scholar
Hare, TA, Hakimi, S and Rangel, A (2014) Activity in dlPFC and its effective connectivity to vmPFC are associated with temporal discounting. Frontiers in Neuroscience 8, 50.Google Scholar
Hayden, BY (2015) Time discounting and time preference in animals: a critical review. Psychonomic Bulletin & Review 23, 39–53.Google Scholar
Heerey, EA, Matveeva, TM and Gold, JM (2011) Imagining the future: degraded representations of future rewards and events in schizophrenia. Journal of Abnormal Psychology 120, 483–489.Google Scholar
Heil, SH, Johnson, MW, Higgins, ST and Bickel, WK (2006) Delay discounting in currently using and currently abstinent cocaine-dependent outpatients and non-drug-using matched controls. Addictive Behaviors 31, 1290–1294.Google Scholar
Jachimowicz, JM, Chafik, S, Munrat, S, Prabhu, JC and Weber, EU (2017) Community trust reduces myopic decisions of low-income individuals. Proceedings of the National Academy of Sciences of the USA 114, 5401–5406.Google Scholar
Jackson, JNS and MacKillop, J (2016) Attention-deficit/hyperactivity disorder and monetary delay discounting: a meta-analysis of case-control studies. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 1, 316–325.Google Scholar
Jarmolowicz, DP, Cherry, JBC, Reed, DD, Bruce, JM, Crespi, JM, Lusk, JL and Bruce, AS (2014) Robust relation between temporal discounting rates and body mass. Appetite 78, 63–67.Google Scholar
Jaroni, JL, Wright, SM, Lerman, C and Epstein, LH (2004) Relationship between education and delay discounting in smokers. Addictive Behaviors 29, 1171–1175.Google Scholar
Jimura, K, Chushak, MS and Braver, TS (2013) Impulsivity and self-control during intertemporal decision making linked to the neural dynamics of reward value representation. The Journal of Neuroscience 33, 344–357.Google Scholar
Jimura, K, Chushak, MS, Westbrook, A and Braver, TS (2018) Intertemporal decision-making involves prefrontal control mechanisms associated with working memory. Cerebral Cortex 28, 1105–1116.Google Scholar
Johnson, MW (2012) An efficient operant choice procedure for assessing delay discounting in humans: initial validation in cocaine-dependent and control individuals. Experimental and Clinical Psychopharmacology 20, 191–204.Google Scholar
Johnson, MW and Bickel, WK (2002) Within-subject comparison of real and hypothetical money rewards in delay discounting. Journal of the Experimental Analysis of Behavior 77, 129–146.Google Scholar
Kable, JW and Glimcher, PW (2007) The neural correlates of subjective value during intertemporal choice. Nature Neuroscience 10, 1625–1633.Google Scholar
Kable, JW and Glimcher, PW (2010) An ‘as soon as possible’ effect in human intertemporal decision making: behavioral evidence and neural mechanisms. Journal of Neurophysiology 103, 2513–2531.Google Scholar
Kim, B, Sung, YS and McClure, SM (2012) The neural basis of cultural differences in delay discounting. Philosophical Transactions of the Royal Society B: Biological Sciences 367, 650–656.Google Scholar
King, JA, Geisler, D, Bernardoni, F, Ritschel, F, Böhm, I, Seidel, M, Mennigen, E, Ripke, S, Smolka, MN, Roessner, V and Ehrlich, S (2016) Altered neural efficiency of decision making during temporal reward discounting in anorexia nervosa. Journal of the American Academy of Child & Adolescent Psychiatry 55, 972–979.Google Scholar
Kirby, KN (2009) One-year temporal stability of delay-discount rates. Psychonomic Bulletin & Review 16, 457–462.Google Scholar
Kirby, KN, Petry, NM and Bickel, WK (1999) Heroin addicts have higher discount rates for delayed rewards than non-drug-using controls. Journal of Experimental Psychology: General 128, 78–87.Google Scholar
Kirby, KN, Winston, GC and Santiesteban, M (2005) Impatience and grades: delay-discount rates correlate negatively with college GPA. Learning and Individual Differences 15, 213–222.Google Scholar
Kolling, N, Wittmann, MK, Behrens, TEJ, Boorman, ED, Mars, RB and Rushworth, MFS (2016) Value, search, persistence and model updating in anterior cingulate cortex. Nature Neuroscience 19, 1280–1285.Google Scholar
Lamb, RJ, Maguire, DR, Ginsburg, BC, Pinkston, JW and France, CP (2016) Determinants of choice, and vulnerability and recovery in addiction. Behavioural Processes 127, 35–42.Google Scholar
Lawrance, EC (1991) Poverty and the rate of time preference: evidence from panel data. Journal of Political Economy 99, 54–77.Google Scholar
Lempert, KM, Glimcher, PW and Phelps, EA (2015) Emotional arousal and discount rate in intertemporal choice are reference dependent. Journal of Experimental Psychology: General 144, 366–373.Google Scholar
Lempert, KM and Phelps, EA (2016) The malleability of intertemporal choice. Trends in Cognitive Sciences 20, 64–74.Google Scholar
Lempert, KM, Speer, ME, Delgado, MR and Phelps, EA (2017) Positive autobiographical memory retrieval reduces temporal discounting. Social Cognitive and Affective Neuroscience 12, 1584–1593.Google Scholar
Levy, DJ and Glimcher, PW (2012) The root of all value: a neural common currency for choice. Current Opinion in Neurobiology 22, 1027–1038.Google Scholar
Loewenstein, GF (1988) Frames of mind in intertemporal choice. Management Science 34, 200–214.Google Scholar
Logue, AW, Tobin, H, Chelonis, JJ, Wang, RY, Geary, N and Schachter, S (1992) Cocaine decreases self-control in rats: a preliminary report. Psychopharmacology 109, 245–247.Google Scholar
Lopez-Guzman, S, Konova, AB, Louie, K and Glimcher, PW (2018) Risk preferences impose a hidden distortion on measures of choice impulsivity. PLoS ONE 13, e0191357.Google Scholar
MacKillop, J, Amlung, MT, Few, LR, Ray, LA, Sweet, LH and Munafò, MR (2011) Delayed reward discounting and addictive behavior: a meta-analysis. Psychopharmacology 216, 305–321.Google Scholar
Maia, TV, Huys, QJM and Frank, MJ (2017) Theory-based computational psychiatry. Biological Psychiatry 82, 382–384.Google Scholar
Mason, L, O'Sullivan, N, Blackburn, M, Bentall, R and El-Deredy, W (2012) I want it now! Neural correlates of hypersensitivity to immediate reward in hypomania. Biological Psychiatry 71, 530–537.Google Scholar
Mazur, J (1987) An adjusting procedure for studying delayed reinforcement. In Commons, ML, Mazur, JE and Nevin, JA (eds), Quantitative Analyses of Behavior: Vol. 5: The Effect of Delay and of Intervening Events on Reinforcement Value. Hillsdale, NJ: Erlbaum, pp. 55–73.Google Scholar
Mazur, JE and Biondi, DR (2009) Delay-amount tradeoffs in choices by pigeons and rats: hyperbolic versus exponential discounting. Journal of the Experimental Analysis of Behavior 91, 197–211.Google Scholar
McClelland, J, Dalton, B, Kekic, M, Bartholdy, S, Campbell, IC and Schmidt, U (2016) A systematic review of temporal discounting in eating disorders and obesity: behavioural and neuroimaging findings. Neuroscience and Biobehavioral Reviews 71, 506–528.Google Scholar
McClure, SM, Laibson, DI, Loewenstein, G and Cohen, JD (2004) Separate neural systems value immediate and delayed monetary rewards. Science 306, 503–507.Google Scholar
McGuire, JT and Kable, JW (2012) Decision makers calibrate behavioral persistence on the basis of time-interval experience. Cognition 124, 216–226.Google Scholar
Meier, S and Sprenger, CD (2012) Time discounting predicts creditworthiness. Psychological Science 23, 56–58.Google Scholar
Miedl, SF, Wiswede, D, Marco-Pallarés, J, Ye, Z, Fehr, T, Herrmann, M and Münte, TF (2015) The neural basis of impulsive discounting in pathological gamblers. Brain Imaging and Behavior 9, 887–898.Google Scholar
Miyazaki, K, Miyazaki, KW and Doya, K (2011) Activation of dorsal raphe serotonin neurons underlies waiting for delayed rewards. The Journal of Neuroscience 31, 469–479.Google Scholar
Mobini, S, Chiang, T-J, Ho, M-Y, Bradshaw, CM and Szabadi, E (2000) Effects of central 5-hydroxytryptamine depletion on sensitivity to delayed and probabilistic reinforcement. Psychopharmacology 152, 390–397.Google Scholar
Monterosso, JR, Ainslie, G, Xu, J, Cordova, X, Domier, CP and London, ED (2007) Frontoparietal cortical activity of methamphetamine-dependent and comparison subjects performing a delay discounting task. Human Brain Mapping 28, 383–393.Google Scholar
Myerson, J, Green, L and Warusawitharana, M (2001) Area under the curve as a measure of discounting. Journal of the Experimental Analysis of Behavior 76, 235–243.Google Scholar
Olson, EA, Collins, PF, Hooper, CJ, Muetzel, R, Lim, KO and Luciana, M (2009) White matter integrity predicts delay discounting behavior in 9- to 23-year-olds: a diffusion tensor imaging study. Journal of Cognitive Neuroscience 21, 1406–1421.Google Scholar
Owens, MM, Gray, JC, Amlung, MT, Oshri, A, Sweet, LH and MacKillop, J (2017) Neuroanatomical foundations of delayed reward discounting decision making. NeuroImage 161, 261–270.Google Scholar
Palombo, DJ, Keane, MM and Verfaellie, M (2015) The medial temporal lobes are critical for reward-based decision making under conditions that promote episodic future thinking. Hippocampus 25, 345–353.Google Scholar
Peters, J and Büchel, C (2010) Episodic future thinking reduces reward delay discounting through an enhancement of prefrontal-mediotemporal interactions. Neuron 66, 138–148.Google Scholar
Peters, J and Büchel, C (2011) The neural mechanisms of inter-temporal decision-making: understanding variability. Trends in Cognitive Sciences 15, 227–239.Google Scholar
Peters, J and D'Esposito, M (2016) Effects of medial orbitofrontal cortex lesions on self-control in intertemporal choice. Current Biology 26, 2625–2628.Google Scholar
Petry, NM (2001) Delay discounting of money and alcohol in actively using alcoholics, currently abstinent alcoholics, and controls. Psychopharmacology 154, 243–250.Google Scholar
Pine, A, Shiner, T, Seymour, B and Dolan, RJ (2010) Dopamine, time, and impulsivity in humans. Journal of Neuroscience 30, 8888–8896.Google Scholar
Pinto, A, Steinglass, JE, Greene, AL, Weber, EU and Simpson, HB (2014) Capacity to delay reward differentiates obsessive-compulsive disorder and obsessive-compulsive personality disorder. Biological Psychiatry 75, 653–659.Google Scholar
Radu, PT, Yi, R, Bickel, WK, Gross, JJ and McClure, SM (2011) A mechanism for reducing delay discounting by altering temporal attention. Journal of the Experimental Analysis of Behavior 96, 363–385.Google Scholar
Read, D and Read, N (2004) Time discounting over the lifespan. Organizational Behavior and Human Decision Processes 94, 22–32.Google Scholar
Reynolds, B, Ortengren, A, Richards, JB and de Wit, H (2006) Dimensions of impulsive behavior: personality and behavioral measures. Personality and Individual Differences 40, 305–315.Google Scholar
Ritschel, F, King, JA, Geisler, D, Flohr, L, Neidel, F, Boehm, I, Seidel, M, Zwipp, J, Ripke, S, Smolka, MN, Roessner, V and Ehrlich, S (2015) Temporal delay discounting in acutely ill and weight-recovered patients with anorexia nervosa. Psychological Medicine 45, 1229–1239.Google Scholar
Rosati, AG, Stevens, JR, Hare, B and Hauser, MD (2007) The evolutionary origins of human patience: temporal preferences in chimpanzees, bonobos, and human adults. Current Biology 17, 1663–1668.Google Scholar
Sawicki, P and Białek, M (2016) Side effects in time discounting procedures: fixed alternatives become the reference point. PLoS ONE 11, e0165245.Google Scholar
Schacter, DL, Addis, DR and Buckner, RL (2007) Remembering the past to imagine the future: the prospective brain. Nature Reviews Neuroscience 8, 657–661.Google Scholar
Schweighofer, N, Bertin, M, Shishida, K, Okamoto, Y, Tanaka, SC, Yamawaki, S and Doya, K (2008) Low-serotonin levels increase delayed reward discounting in humans. Journal of Neuroscience 28, 4528–4532.Google Scholar
Senecal, N, Wang, T, Thompson, E and Kable, JW (2012) Normative arguments from experts and peers reduce delay discounting. NIH Public Access Judgment and Decision Making 7, 568–589.Google Scholar
Shah, AK, Mullainathan, S and Shafir, E (2012) Some consequences of having too little. Science 338, 682–685.Google Scholar
Shen, B, Yin, Y, Wang, J, Zhou, X, McClure, SM and Li, J (2016) High-definition tDCS alters impulsivity in a baseline-dependent manner. NeuroImage 143, 343–352.Google Scholar
Shenhav, A, Cohen, JD and Botvinick, MM (2016) Dorsal anterior cingulate cortex and the value of control. Nature Neuroscience 19, 1286–1291.Google Scholar
Silverman, IW (2003) Gender differences in delay of gratification: a meta-analysis. Sex Roles 49, 451–463.Google Scholar
Snider, SE, LaConte, SM and Bickel, WK (2016) Episodic future thinking: expansion of the temporal window in individuals with alcohol dependence. Alcoholism: Clinical and Experimental Research 40, 1558–1566.Google Scholar
Stein, JS, Wilson, AG, Koffarnus, MN, Daniel, TO, Epstein, LH and Bickel, WK (2016) Unstuck in time: episodic future thinking reduces delay discounting and cigarette smoking. Psychopharmacology 233, 3771–3778.Google Scholar
Steinglass, JE, Figner, B, Berkowitz, S, Simpson, HB, Weber, EU and Walsh, BT (2012) Increased capacity to delay reward in anorexia nervosa. Journal of the International Neuropsychological Society 18, 773–780.Google Scholar
Steinglass, JE, Lempert, KM, Choo, T-H, Kimeldorf, MB, Wall, M, Walsh, BT, Fyer, AJ, Schneier, FR and Simpson, HB (2017) Temporal discounting across three psychiatric disorders: anorexia nervosa, obsessive compulsive disorder, and social anxiety disorder. Depression and Anxiety 34, 463–470.Google Scholar
Steward, T, Mestre-Bach, G, Vintró-Alcaraz, C, Agüera, Z, Jiménez-Murcia, S, Granero, R and Fernández-Aranda, F (2017) Delay discounting of reward and impulsivity in eating disorders: from anorexia nervosa to binge eating disorder. European Eating Disorders Review 25, 601–606.Google Scholar
Szuhany, KL, MacKenzie, D and Otto, MW (2018) The impact of depressed mood, working memory capacity, and priming on delay discounting. Journal of Behavior Therapy and Experimental Psychiatry 60, 37–41.Google Scholar
Tanaka, T, Camerer, CF and Nguyen, Q (2010) Risk and time preferences: linking experimental and household survey data from Vietnam. American Economic Review 100, 557–571.Google Scholar
Tsukayama, E and Duckworth, AL (2010) Domain-specific temporal discounting and temptation. Judgment and Decision Making 5, 72–82.Google Scholar
Turner, BM, Rodriguez, CA, Liu, Q, Molloy, MF, Hoogendijk, M and McClure, SM (2018) On the neural and mechanistic bases of self-control. Cerebral Cortex ePub ahead of print. doi: 10.1093/cercor/bhx355.Google Scholar
U.S. Department of Health and Human Services, National Institutes of Health, National Institute of Mental Health (2016) Behavioral Assessment Methods for RDoC Constructs. Retrieved from https://www.nimh.nih.gov/about/advisory-boards-and-groups/namhc/reports/behavioral-assessment-methods-for-rdoc-constructs.shtml.Google Scholar
van den Bos, W, Rodriguez, CA, Schweitzer, JB and McClure, SM (2014) Connectivity strength of dissociable striatal tracts predict individual differences in temporal discounting. The Journal of Neuroscience 34, 10298–10310.Google Scholar
Vanderveldt, A, Oliveira, L and Green, L (2016) Delay discounting: pigeon, rat, human – does it matter? Journal of Experimental Psychology: Animal Learning and Cognition 42, 141–162.Google Scholar
Van Dijk, FE, Mostert, J, Glennon, J, Onnink, M, Dammers, J, Vasquez, AA, Kan, C, Verkes, RJ, Hoogman, M, Franke, B and Buitelaar, JK (2017) Five factor model personality traits relate to adult attention-deficit/hyperactivity disorder but not to their distinct neurocognitive profiles. Elsevier Psychiatry Research 258, 255–261.Google Scholar
Vloet, TD, Marx, I, Kahraman-Lanzerath, B, Zepf, FD, Herpertz-Dahlmann, B and Konrad, K (2010) Neurocognitive performance in children with ADHD and OCD. Journal of Abnormal Child Psychology 38, 961–969.Google Scholar
Volkow, ND and Morales, M (2015) The brain on drugs: from reward to addiction. Cell 162, 712–725.Google Scholar
Washio, Y, Higgins, ST, Heil, SH, McKerchar, TL, Badger, GJ, Skelly, JM and Dantona, RL (2011) Delay discounting is associated with treatment response among cocaine-dependent outpatients. Experimental and Clinical Psychopharmacology 19, 243–248.Google Scholar
Weber, EU, Johnson, EJ, Milch, KF, Chang, H, Brodscholl, JC and Goldstein, DG (2007) Asymmetric discounting in intertemporal choice: a query-theory account. Psychological Science 18, 516–523.Google Scholar
Wesley, MJ and Bickel, WK (2014) Remember the future II: meta-analyses and functional overlap of working memory and delay discounting. Biological Psychiatry 75, 435–448.Google Scholar
Wierenga, CE, Bischoff-Grethe, A, Melrose, AJ, Irvine, Z, Torres, L, Bailer, UF, Simmons, A, Fudge, JL, McClure, SM, Ely, A and Kaye, WH (2015) Hunger does not motivate reward in women remitted from anorexia nervosa. Biological Psychiatry 77, 642–652.Google Scholar
Winstanley, CA, Dalley, JW, Theobald, DEH and Robbins, TW (2003) Global 5-HT depletion attenuates the ability of amphetamine to decrease impulsive choice on a delay-discounting task in rats. Psychopharmacology 170, 320–331.Google Scholar
Yu, LQ, Lee, S, Katchmar, N, Satterthwaite, TD, Kable, JW and Wolf, DH (2017) Steeper discounting of delayed rewards in schizophrenia but not first-degree relatives. Psychiatry Research 252, 303–309.Google Scholar
Yu, R (2012) Regional white matter volumes correlate with delay discounting. PLoS ONE 7, e32595.Google Scholar