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Assortative mating among in-patients with primary affective disorder

Published online by Cambridge University Press:  09 July 2009

Kathleen Ries Merikangas  and
Duane G. Spiker
Kathleen Ries Merikangas*
Affiliation:
Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
Duane G. Spiker
Affiliation:
Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
*
1 Address for correspondence: Dr Kathleen Merikangas, Yale University School of Medicine. 904 Howard Avenue, Suite 2A, New Haven. CT 06519. USA
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Synopsis

Assortative mating among 56 married in-patients with primary affective disorders and their spouses was studied by determining the prevalence of psychiatric illness among the spouses by means of direct interviews and standardized diagnostic criteria. A high degree of assortative mating among both male and female patients was observed for total psychiatric illness, broad spectrum affective illness and major depression. A significantly higher prevalence of psychiatric and affective illness was found among the first-degree relatives of the ill spouses when compared with the first-degree relatives of the well spouses. There was a high degree of diagnostic concordance between the patients and spouses for both affective illness and alcoholism, with a higher degree of assortative mating among bipolar patients than among unipolar patients. The finding in this study of an increased prevalence of psychiatric disorder in the first-degree relatives of the ill spouses would support the hypothesis that there is a tendency for individuals with a predisposition to psychiatric illness to marry, rather than the existence of a marital interaction which causes an increased concordance for psychiatric illness.

Type
Research Article
Information
Psychological Medicine , Volume 12 , Issue 4 , November 1982 , pp. 753 - 764
Copyright
Copyright © Cambridge University Press 1982

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References

Agulnik, P. L. (1970). The spouse of the phobic patient. British Journal of Psychiatry 117. 59–67.CrossRefGoogle ScholarPubMed
Andreasen, N. C., Endicott, J., Spitzer, R. L. & Winokur, G. (1977). The family history method using diagnostic criteria. Archives of General Psychiatry 34, 1229–1235.CrossRefGoogle ScholarPubMed
Baron, M., Mendlewicz, J., Gruen, R., Asnis, L. & Fieve, R. R. (1981). Assortative mating in affective disorders. Journal of Affective Disorders 3, 167–171.CrossRefGoogle ScholarPubMed
Bowen, M. (1978). Family Therapy in Clinical Practice. Aronson: New York.Google Scholar
Breese, E. L. (1956). The genetical consequences of assortative mating. Heredity 10, 323–343.CrossRefGoogle Scholar
Buck, C. W. & Ladd, K. L. (1965). Psychoneurosis in marital partners. British Journal of Psychiatry 111, 587–590.CrossRefGoogle ScholarPubMed
Burgess, E. W. & Wallin, P. (1943). Homogamy in social characteristics. American Journal of Sociology 49, 109–124.CrossRefGoogle Scholar
Burgess, E. W. & Wallin, P. (1944). Homogamy in personality characteristics. Journal of Abnormal Social Psychology 39,475–481.CrossRefGoogle Scholar
Chodoff, P. (1972). The depressive personality: a critical review. Archires of General Psychiatry 27. 666–672.CrossRefGoogle ScholarPubMed
Cloninger, C. R., Reich, T. & Guze, S. B. (1975 a). The multifactorial model of disease transmission. II: Sex differences in the familial transmission of sociopathy (antisocial personality). British Journal of Psrchiatry 127. 11–22.CrossRefGoogle ScholarPubMed
Cloninger, C. R., Reich, T. & Guze, S. B. (1975 b). The multifactorial model of disease transmission. III: Familial relationship between sociopathy and hysteria (Briquet's Syndrome). British Journal of Psychiatry 127. 23–32.CrossRefGoogle ScholarPubMed
Cloninger, C. R., Rice, J. & Reich, T. (1979). Multifactorial inheritance with cultural transmission and assortative mating. II: A general model of combined polygenic and cultural inheritance. American Journal of Human Genetics 31. 176–198.Google Scholar
Cohen, J. (1960). A coefficient of agreement for nominal scales. Educational and Psychological Measurement 20,37–46.CrossRefGoogle Scholar
Crow, J. F. & Felsenstein, J. (1968). The effect of assortative mating on the genetic composition of a population. Eugenics Quarterly 15. 85–97.CrossRefGoogle ScholarPubMed
Crow, J. F. & Kimura, M. (1970). An Introduction to Population Genetics Theory. Harper: New York.Google Scholar
Dixon, W. J. & Brown, M. B. (eds.) (1977). BMDP-79: Biomedical Computer Programs P-series. University of California Press: Berkeley.Google Scholar
Dunner, D. L., Fleiss, J., Addonizio, G. & Fieve, R. (1976). Assortative mating in primary affective disorder. Biological Psychiatry 11, 43–51.Google ScholarPubMed
Eckland, B. (1968). Theories of mate selection. Eugenics Quarterly 15. 71–143.CrossRefGoogle ScholarPubMed
Endicott, J. & Spitzer, R. L. (1978). A diagnostic interview: The Schedule for Affective Disorders and Schizophrenia. Archives of General Psychiatry 35, 837–844.CrossRefGoogle ScholarPubMed
Feighner, J., Robins, E., Guze, S., Woodruff, R.. Winokur, G. & Munoz, R. (1972). Diagnostic criteria for use in psychiatric research. Archives of General Psychiatry 26, 57–63.CrossRefGoogle ScholarPubMed
Fleiss, J. (1971). Measuring nominal scale agreement among many raters. Psychological Bulletin 76, 378–382.CrossRefGoogle Scholar
Fleiss, J., Spitzer, R., Endicott, J. & Cohen, J. (1972). Quantification of agreement in multiple psychiatric diagnosis. Archives of General Psychiatry 26, 168–171.CrossRefGoogle ScholarPubMed
Gershon, E. S., Dunner, D. L., Sturt, L. & Goodwin, F. K. (1973). Assortative mating in the affective disorders. Biological Psychiatry 7, 63–74.Google ScholarPubMed
Gershon, E. S., Mark, A., Cohen, N., Belizon, N., Baron, M. & Knobe, K. (1975). Transmitted factors in the morbid risk of affective disorders: a controlled study. Journal of Psychiatric Research 12. 283–299.CrossRefGoogle Scholar
Gregory, I. (1959). Husbands and wives admitted to mental hospital. Journal of Mental Science 105, 457–562.CrossRefGoogle ScholarPubMed
Guze, S. B., Goodwin, D. W. & Crane, J. B. (1970). A psychialric study of the wives of convicted felons: an example of assortative mating. American Journal of Psychiatry 126, 115–118.CrossRefGoogle Scholar
Hagnell, O. & Kreitman, N. (1974). Mental illness in married pairs in a total population. British Journal of Psychiatry 125, 203–302.CrossRefGoogle Scholar
Hall, D. J., Baldwin, J. A. & Robertson, N. C. (1971). Mental illness in married pairs: Problems in estimating incidence. In Aspects in the Epidemiology of Mental Illness: Studies in Record Linkage (ed. Baldwin, J. A.), pp. 115–134. Little, Brown: Boston.Google Scholar
Hare, E. H. & Shaw, G. K. (1965). The patient's spouse and concordance on neuroticism. British Journal of Psychiatry 111, 102–103.CrossRefGoogle Scholar
Helzer, J. E., Robins, L. N., Taibleson, M., Woodruff, R., Reich, T. & Wish, E. (1977 a). Reliability of psychiatric diagnosis: I. A methodological review. Archives of General Psychiatry 34. 129–133.CrossRefGoogle Scholar
Helzer, J. E., Clayton, P. J., Pambakian, R.Reich, T., Woodruff, R. & Reveley, M. (1977 b). Reliability of psychiatric diagnosis: II. The test/retest reliability of diagnostic classification. Archives of General Psychiatry 34, 136–141.CrossRefGoogle ScholarPubMed
Hirschfeld, R. M. A. & Klerman, G. L. (1979). Personality attributes and affective disorders. American Journal of Psychiatry 136. 67–70.Google ScholarPubMed
Hollingshead, A. B. (1950). Cultural factors in the selection of marriage mates. American Sociological Review 15. 619–627.CrossRefGoogle Scholar
Kaplan, E. L. & Meier, P. (1958). Nonparametric estimation from incomplete observations. Journal of the American Statistical Association 53, 457.CrossRefGoogle Scholar
Kendell, R. E. & DiScipio, W. J. (1968). Eysenck personality inventory scores of patients with depressive illnesses. British Journal of Psychiatry 114, 767–770.CrossRefGoogle ScholarPubMed
Kendell, R. E. & DiScipio, W. J. (1970). Obsessional symptoms and personality traits in patients with depressive illness. Psychological Medicine 1. 65–72.CrossRefGoogle Scholar
Kreitman, N. (1962). Mental disorder in married couples. Journal of Mental Science 108, 438.CrossRefGoogle ScholarPubMed
Kreitman, N. (1964). The patient's spouse. British Journal of Psychiatry 110, 159–173.CrossRefGoogle ScholarPubMed
Kreitman, N. (1968). Married couples admitted to mental hospital. British Journal of Psychiatry 114, 699–718.CrossRefGoogle ScholarPubMed
Leckman, J. F., Sholomskas, D., Thompson, W. D., Belanger, A. & Weissman, M. M. (1982). Best estimate of lifetime psychiatric diagnosis: a methodologic study. Archives of General Psychiaty (in the press).CrossRefGoogle Scholar
Li, C. C. (1975). Assortative mating in man. In Memorias de la II Reunion Nacionale de la Sociedad Mexicana de Genetica: Mazatlan Sin., Marzo 1974. Ed. SMG. Con el patrocinio de fomento Cultural BANAMEX, Mex, D. F.. pp. 48–108.Google Scholar
Maxmen, J., Tucker, G. & LeBow, M. (1974). Rational Hospital Psychiatry. Brunner Mazel: New York.Google Scholar
Mazure, C. & Gershon, E. S. (1979). Blindness and reliability in lifetime psychiatric diagnosis. Archives of Geiteral Psychiatry 36. 521–525.CrossRefGoogle ScholarPubMed
Mendlewicz, J., Fleiss, J. L., Cataldo, M. & Ranier, J. D. (1975). Accuracy of the family history method in affective illness. Archives of General Psychiatry 32, 309–314.CrossRefGoogle ScholarPubMed
Merikangas, K. R. (1982). Assortative mating for psychiatric disorder and psychological traits. Archives of General Psychiatry (in the press).CrossRefGoogle Scholar
Negri, F., Melica, A. M., Zuliani, R. & Smeraldi, E. (1979). Assortative mating and affective disorders. Journal of Affective Disorders 1, 247–253.CrossRefGoogle ScholarPubMed
Negri, F., Melica, A. M., Zuliani, R., Gasperini, M., Macciardi, F. & Smeraldi, E. (1981). Genetic implications in assortative mating of affective disorders. British Journal of Psychiatry 138, 236–239.Google ScholarPubMed
Nielsen, J. (1964). Mental disorders in married couples (assortative mating). British Journal of Psychiatry 110, 683–697.CrossRefGoogle ScholarPubMed
Ovenstone, I. M. K. (1973). The development of neurosis in the wives of neurotic men. Part II: Marital role functions and marital tension. British Journal of Psychiatry 122. 711–717.CrossRefGoogle Scholar
Paykel, E. S., Myers, J. K., Dienelt, M. N., Klerman, G. L., Lindenthal, J. J. & Pepper, M. P. (1969). Life events and depression: a controlled study. Archives of General Psychiatry 21, 753–760.CrossRefGoogle ScholarPubMed
Paykel, E. S., Klerman, G. L. & Prusoff, B. A. (1976). Personality and symptom pattern in depression. British Journal of Psychiatry 129, 327–334.CrossRefGoogle ScholarPubMed
Pearson, K. & Lee, A. (1903). On the laws of inheritance in man. Biometrika 2. 357–462.CrossRefGoogle Scholar
Penrose, L. S. (1944). Mental illness in husband and wife: a contribution to the study of assortative mating in man. Psychiatry Quarterly Supplentent 18. 161–166.CrossRefGoogle Scholar
Rao, D.C., Morton, N. E. & Yee, S. (1976). Resolution of cultural and biological inheritance by path analysis. American Journal of Human Genetics 28, 228–242.Google ScholarPubMed
Richardson, H. M. (1939). Studies of mental resemblance between husbands and wives and between friends. Psychological Bulletin 36, 104–120.CrossRefGoogle Scholar
Ryle, A. & Hamilton, M. (1962). Neurosis in fifty married couples. Journal of Mental Science 108, 265–273.CrossRefGoogle ScholarPubMed
Schooley, M. (1936). Personality resemblances among married couples. Journal of Abnormal Social Psychiatry 31. 340–347.CrossRefGoogle Scholar
Slater, E. & Woodside, M. (1951). Patterns of Marriage. Cassell: London.Google Scholar
Spitzer, R. L., Endicott, J. & Robins, E. (1977). Research diagnostic criteria (RDC) for a selected group of functional disorders. Biometrics Research, New York State Psychiatric Institute: New York.Google Scholar
Spitzer, R. L., Endicott, J. & Robins, E. (1978). Research diagnostic criteria: rationale and reliability. Archives of General Psychiatry 35.773–782.CrossRefGoogle ScholarPubMed
Tharp, R. (1963). Psychological patterning in marriage. Psychological Bulletin 60. 97–117.CrossRefGoogle ScholarPubMed
Thompson, W. D. & Weissman, M. M. (1981). Quantifying lifetime risk of psychiatric disorder. Journal of Psychiatric Research 16, 113–126.CrossRefGoogle ScholarPubMed
Thompson, W. D., Orvaschel, H., Prusoff, B. A. & Kidd, K. K. (1982). An evaluation of the family history method for ascertaining psychiatric disorders. Archives of General Psychiatry 39. 53–58.CrossRefGoogle ScholarPubMed
Vandenberg, S. G. (1972). Assortative mating or who marries whom? Behaviour Genetics 2. 127–157.CrossRefGoogle Scholar
Vogel, F. & Motulsky, V. (1979). Human Genetics, pp. 413–414. Springer-Verlag: Berlin.Google Scholar
Warren, B. L. (1966). A multiple variable approach to the assortative mating phenomenon. Eugenics Quarterly 13. 285–290.CrossRefGoogle Scholar
Weissman, M. M. & Klerman, G. L. (1977). Sex differences and the epidemiology of depression. Archives of General Psychiatry 34, 98–111.CrossRefGoogle ScholarPubMed
Weissman, M. M. & Myers, J. K. (1978). Affective disorders in a US urban community. Archives of General Psychiatry 35, 1304–1311.CrossRefGoogle Scholar
Weissman, M. M. & Myers, J. K. (1980). Clinical depression in alcoholism. American Journal of Psychiatry 137. 372–373.Google ScholarPubMed
Weissman, M. M., Kidd, K. K. & Prusoff, B. A. (1982). Variability in the rates of affective disorders in the relatives of severe and mild major nonbipolar depressives and normals. Archives of General Psychiatry (in the press).CrossRefGoogle Scholar
Wright, S. (1921). Systems of mating. I: The biometric relations between parent and offspring. II: The effects of inbreeding on the genetic composition of a population. III: Assortative mating based on Somatic resemblance. IV: The effects of selection. Genetics 6, 111–123, 124 143, 144 161, 162 166.CrossRefGoogle Scholar