Hostname: page-component-cd9895bd7-7cvxr Total loading time: 0 Render date: 2024-12-27T19:07:48.989Z Has data issue: false hasContentIssue false

The association between psychotic experiences and traumatic life events: the role of the intention to harm

Published online by Cambridge University Press:  14 January 2018

Tais Silveira Moriyama
Affiliation:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Brasília, Brazil Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil National Institute of Developmental Psychiatry for Children and Adolescents (INCT-CNPq), São Paulo, Brazil Department of Psychiatry and Psychology, School of Mental Health and Neuroscience (MHeNS), Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands
Marjan Drukker
Affiliation:
Department of Psychiatry and Psychology, School of Mental Health and Neuroscience (MHeNS), Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands
Ary Gadelha
Affiliation:
Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil National Institute of Developmental Psychiatry for Children and Adolescents (INCT-CNPq), São Paulo, Brazil
Pedro Mario Pan
Affiliation:
Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil National Institute of Developmental Psychiatry for Children and Adolescents (INCT-CNPq), São Paulo, Brazil
Giovanni Abrahão Salum
Affiliation:
National Institute of Developmental Psychiatry for Children and Adolescents (INCT-CNPq), São Paulo, Brazil Department of Psychiatry, Federal University of Rio Grande do Sul, Porto Alegre, Brazil
Gisele Gus Manfro
Affiliation:
National Institute of Developmental Psychiatry for Children and Adolescents (INCT-CNPq), São Paulo, Brazil Department of Psychiatry, Federal University of Rio Grande do Sul, Porto Alegre, Brazil
Jair de Jesus Mari
Affiliation:
Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil National Institute of Developmental Psychiatry for Children and Adolescents (INCT-CNPq), São Paulo, Brazil
Eurípedes Constantino Miguel
Affiliation:
National Institute of Developmental Psychiatry for Children and Adolescents (INCT-CNPq), São Paulo, Brazil Department & Institute of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil
Luis Augusto Rohde
Affiliation:
National Institute of Developmental Psychiatry for Children and Adolescents (INCT-CNPq), São Paulo, Brazil Department of Psychiatry, Federal University of Rio Grande do Sul, Porto Alegre, Brazil
Guilherme Vanoni Polanczyk
Affiliation:
National Institute of Developmental Psychiatry for Children and Adolescents (INCT-CNPq), São Paulo, Brazil Department & Institute of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil
Jim van Os*
Affiliation:
Department of Psychiatry and Psychology, School of Mental Health and Neuroscience (MHeNS), Maastricht University Medical Centre (MUMC), Maastricht, The Netherlands Department of Psychosis Studies, King's College London, King's Health Partners, London, UK Department of Psychiatry, Brain Centre Rudolf Magnus, Utrecht University Medical Centre, Utrecht, The Netherlands
Rodrigo Affonseca Bressan
Affiliation:
Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil National Institute of Developmental Psychiatry for Children and Adolescents (INCT-CNPq), São Paulo, Brazil Department of Psychosis Studies, King's College London, King's Health Partners, London, UK
*
Author for correspondence: Jim van Os, E-mail: [email protected], [email protected]

Abstract

Background

Previous work showed traumatic life events (TLE) with intention to harm, like bullying and abuse, to be more strongly associated with psychotic experiences (PE) than other types of trauma, like accidents. However, this association is subject to reporting bias and can be confounded by demographic characteristics and by differences in dose of exposure across different trauma categories. We studied the association between TLE with and without intention to harm and PE, taking into account potential confounders and biases.

Methods

A total of 2245 children and adolescents aged 6–14 years were interviewed by psychologists. The interview included the presence of 20 PE (both self-report and psychologist evaluation). In addition, parents provided information on child exposure to trauma, mental health and PE.

Results

Results showed no significant association between TLE without intention to harm only and PE for the three methods of assessment of PE (self-report, parent report and psychologist rating). On the other hand, there was a positive association between PE and TLE in groups exposed to traumatic experiences with intention to harm (with intention to harm only and with and without intention to harm). Results remained significant after controlling for demographic and clinical confounders, but this positive association was no longer significant after adjusting for the number of TLE.

Conclusions

TLE with intention to harm display a stronger association with PE than TLE without intention to harm, and this difference is likely reducible to a greater level of traumatic exposure associated with TLE with intention to harm.

Type
Original Articles
Copyright
Copyright © Cambridge University Press 2018 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Amorim, P, Lecrubier, Y, Weiller, E, Hergueta, T and Sheehan, D (1998) DSM-IH-R psychotic disorders: procedural validity of the Mini International Neuropsychiatric Interview (MINI). Concordance and causes for discordance with the CIDI. European Psychiatry 13, 2634.Google Scholar
Arseneault, L, Cannon, M, Fisher, HL, Polanczyk, G, Moffitt, TE and Caspi, A (2011) Childhood trauma and children's emerging psychotic symptoms: a genetically sensitive longitudinal cohort study. American Journal of Psychiatry 168, 6572.Google Scholar
Associação Brasileira de Empresas de Pesquisa (2012) Critério de Classificação Econômica Brasil – Alterações na aplicação do Critério Brasil, válidas a partir de 01/01/2013. Available at http://www.abep.org/criterio-brasil (Accessed 19 September 2017).Google Scholar
Barrigon, ML, Diaz, FJ, Gurpegui, M, Ferrin, M, Salcedo, MD, Moreno-Granados, J et al. (2015) Childhood trauma as a risk factor for psychosis: a sib-pair study. Journal of Psychiatric Research 70, 130136.Google Scholar
Bartels-Velthuis, AA, van de Willige, G, Jenner, JA, van Os, J and Wiersma, D (2011) Course of auditory vocal hallucinations in childhood: 5-year follow-up study. British Journal of Psychiatry 199, 296302.Google Scholar
Bernstein, DP, Ahluvalia, T, Pogge, D and Handelsman, L (1997) Validity of the childhood trauma questionnaire in an adolescent psychiatric population. Journal of the American Academy of Child and Adolescent Psychiatry 36, 340348.Google Scholar
Bordin, IA, Rocha, MM, Paula, CS, Teixeira, MC, Achenbach, TM, Rescorla, LA et al. (2013) Child behavior checklist (CBCL), youth self-report (YSR) and teacher's report form (TRF): an overview of the development of the original and Brazilian versions. Cadernos de Saúde Publica 29, 1328.Google Scholar
Bourque, F, van der Ven, E and Malla, A (2011) A meta-analysis of the risk for psychotic disorders among first- and second-generation immigrants. Psychological Medicine 41, 897910.Google Scholar
Breslau, N, Kessler, RC, Chilcoat, HD, Schultz, LR, Davis, GC and Andreski, P (1998) Trauma and posttraumatic stress disorder in the community: the 1996 Detroit Area Survey of Trauma. Archives of General Psychiatry 55, 626632.Google Scholar
Caspi, A, McClay, J, Moffitt, TE, Mill, J, Martin, J, Craig, IW et al. (2002) Role of genotype in the cycle of violence in maltreated children. Science 297, 851854.Google Scholar
Caspi, A, Sugden, K, Moffitt, TE, Taylor, A, Craig, IW, Harrington, H et al. (2003) Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301, 386389.Google Scholar
Dong, M, Anda, RF, Felitti, VJ, Dube, SR, Williamson, DF, Thompson, TJ et al. (2004) The interrelatedness of multiple forms of childhood abuse, neglect, and household dysfunction. Child Abuse and Neglect 28, 771784.Google Scholar
Figueiredo, VLM (2001) Uma adaptação brasileira do teste de inteligência WISC-III. Brasília, DF: Curso de Pós-Graduação em Psicologia, Instituto de Psicologia – Universidade de Brasília.Google Scholar
Finkelhor, D, Ormrod, RK and Turner, HA (2007) Poly-victimization: a neglected component in child victimization. Child Abuse and Neglect 31, 726.Google Scholar
Fisher, HL, Schreier, A, Zammit, S, Maughan, B, Munafo, MR, Lewis, G et al. (2013) Pathways between childhood victimization and psychosis-like symptoms in the ALSPAC birth cohort. Schizophrenia Bulletin 39, 10451055.Google Scholar
Fleitlich-Bilyk, B and Goodman, R (2004) Prevalence of child and adolescent psychiatric disorders in southeast Brazil. Journal of the American Academy of Child and Adolescent Psychiatry 43, 727734.Google Scholar
Goodman, R, Ford, T, Richards, H, Gatward, R and Meltzer, H (2000 a) The development and well-being assessment: description and initial validation of an integrated assessment of child and adolescent psychopathology. Journal of Child Psychology and Psychiatry and Allied Disciplines 41, 645655.Google Scholar
Goodman, R, Ford, T, Simmons, H, Gatward, R and Meltzer, H (2000 b) Using the Strengths and Difficulties Questionnaire (SDQ) to screen for child psychiatric disorders in a community sample. British Journal of Psychiatry 177, 534539.Google Scholar
Guloksuz, S, van Nierop, M, Lieb, R, van Winkel, R, Wittchen, HU and van Os, J (2015) Evidence that the presence of psychosis in non-psychotic disorder is environment-dependent and mediated by severity of non-psychotic psychopathology. Psychological Medicine 45, 23892401.Google Scholar
Harley, M, Kelleher, I, Clarke, M, Lynch, F, Arseneault, L, Connor, D et al. (2010) Cannabis use and childhood trauma interact additively to increase the risk of psychotic symptoms in adolescence. Psychological Medicine 40, 16271634.Google Scholar
Herman, JP, Figueiredo, H, Mueller, NK, Ulrich-Lai, Y, Ostrander, MM, Choi, DC et al. (2003) Central mechanisms of stress integration: hierarchical circuitry controlling hypothalamo-pituitary-adrenocortical responsiveness. Frontiers in Neuroendocrinology 24, 151180.Google Scholar
Isvoranu, AM, Borsboom, D, Van Os, J and Guloksuz, S (2016) A network approach to environmental impact in psychotic disorder: brief theoretical framework. Schizophrenia Bulletin 42, 870873.Google Scholar
Kelleher, I and Cannon, M (2011) Psychotic-like experiences in the general population: characterizing a high-risk group for psychosis. Psychological Medicine 41, 16.Google Scholar
Kelleher, I, Connor, D, Clarke, MC, Devlin, N, Harley, M and Cannon, M (2012) Prevalence of psychotic symptoms in childhood and adolescence: a systematic review and meta-analysis of population-based studies. Psychological Medicine 42, 18571863.Google Scholar
Kelleher, I, Harley, M, Lynch, F, Arseneault, L, Fitzpatrick, C and Cannon, M (2008) Associations between childhood trauma, bullying and psychotic symptoms among a school-based adolescent sample. British Journal of Psychiatry 193, 378382.Google Scholar
Kelleher, I, Keeley, H, Corcoran, P, Ramsay, H, Wasserman, C, Carli, V et al. (2013) Childhood trauma and psychosis in a prospective cohort study: cause, effect, and directionality. American Journal of Psychiatry 170, 734741.Google Scholar
Kieling, C, Hutz, MH, Genro, JP, Polanczyk, GV, Anselmi, L, Camey, S et al. (2013) Gene-environment interaction in externalizing problems among adolescents: evidence from the Pelotas 1993 Birth Cohort Study. Journal of Child Psychology and Psychiatry and Allied Disciplines 54, 298304.Google Scholar
Konings, M, Bak, M, Hanssen, M, van Os, J and Krabbendam, L (2006) Validity and reliability of the CAPE: a self-report instrument for the measurement of psychotic experiences in the general population. Acta Psychiatrica Scandinavica 114, 5561.Google Scholar
Krishnan, V, Han, MH, Graham, DL, Berton, O, Renthal, W, Russo, SJ et al. (2007) Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions. Cell 131, 391404.Google Scholar
Lataster, T, van Os, J, Drukker, M, Henquet, C, Feron, F, Gunther, N et al. (2006) Childhood victimisation and developmental expression of non-clinical delusional ideation and hallucinatory experiences: victimisation and non-clinical psychotic experiences. Social Psychiatry and Psychiatric Epidemiology 41, 423428.Google Scholar
Lee, KW, Chan, KW, Chang, WC, Lee, EH, Hui, CL and Chen, EY (2016) A systematic review on definitions and assessments of psychotic-like experiences. Early Intervention in Psychiatry 10, 316.Google Scholar
Linscott, RJ and van Os, J (2013) An updated and conservative systematic review and meta-analysis of epidemiological evidence on psychotic experiences in children and adults: on the pathway from proneness to persistence to dimensional expression across mental disorders. Psychological Medicine 43, 11331149.Google Scholar
Mackie, CJ, Castellanos-Ryan, N and Conrod, PJ (2011) Developmental trajectories of psychotic-like experiences across adolescence: impact of victimization and substance use. Psychological Medicine 41, 4758.Google Scholar
Matheson, SL, Shepherd, AM, Pinchbeck, RM, Laurens, KR and Carr, VJ (2013) Childhood adversity in schizophrenia: a systematic meta-analysis. Psychological Medicine 43, 225238.Google Scholar
Norman, RE, Byambaa, M, De, R, Butchart, A, Scott, J and Vos, T (2012) The long-term health consequences of child physical abuse, emotional abuse, and neglect: a systematic review and meta-analysis. PLoS Medicine 9, e1001349.Google Scholar
Norman, RM and Malla, AK (1993 a) Stressful life events and schizophrenia. I: a review of the research. The British Journal of Psychiatry: the Journal of Mental Science 162, 161166.Google Scholar
Norman, RM and Malla, AK (1993 b) Stressful life events and schizophrenia. II: conceptual and methodological issues. The British Journal of Psychiatry: the Journal of Mental Science 162, 166174.Google Scholar
Polanczyk, G, Moffitt, TE, Arseneault, L, Cannon, M, Ambler, A, Keefe, RS et al. (2010) Etiological and clinical features of childhood psychotic symptoms: results from a birth cohort. Archives of General Psychiatry 67, 328338.Google Scholar
Ribeiro, WS, de Jesus Mari, J, Quintana, MI, Dewey, ME, Evans-Lacko, S, Vilete, LM et al. (2013) The impact of epidemic violence on the prevalence of psychiatric disorders in Sao Paulo and Rio de Janeiro, Brazil. PLoS ONE 8, e63545.Google Scholar
Salum, GA, DeSousa, DA, Manfro, GG, Pan, PM, Gadelha, A, Brietzke, E et al. (2016) Measuring child maltreatment using survey data: a multi-informant higher-order confirmatory factor analysis. Trends in Psychiatry Psychotherapy 38, 2332.Google Scholar
Salum, GA, Gadelha, A, Pan, PM, Moriyama, TS, Graeff-Martins, AS, Tamanaha, AC et al. (2015) High risk cohort study for psychiatric disorders in childhood: rationale, design, methods and preliminary results. International Journal of Methods in Psychiatric Research 24, 5873.Google Scholar
Schreier, A, Wolke, D, Thomas, K, Horwood, J, Hollis, C, Gunnell, D et al. (2009) Prospective study of peer victimization in childhood and psychotic symptoms in a nonclinical population at age 12 years. Archives of General Psychiatry 66, 527536.Google Scholar
Selten, JP and Cantor-Graae, E (2005) Social defeat: risk factor for schizophrenia? British Journal of Psychiatry 187, 101102.Google Scholar
Sheehan, DV, Lecrubier, Y, Sheehan, KH, Amorim, P, Janavs, J, Weiller, E et al. (1998) The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. Journal of Clinical Psychiatry 59(Suppl. 20), 2233; quiz 34–57.Google Scholar
Snijders, T and Bosker, R (1999) Multilevel Analysis, an Introduction to Basic and Advanced Modeling. London: SAGE Publications.Google Scholar
StataCorp (2013) Stata Statistical Software. College Station, TX: StataCorp LP.Google Scholar
Stowkowy, J and Addington, J (2012) Maladaptive schemas as a mediator between social defeat and positive symptoms in young people at clinical high risk for psychosis. Early Intervention in Psychiatry 6, 8790.Google Scholar
Suliman, S, Mkabile, SG, Fincham, DS, Ahmed, R, Stein, DJ and Seedat, S (2009) Cumulative effect of multiple trauma on symptoms of posttraumatic stress disorder, anxiety, and depression in adolescents. Comprehensive Psychiatry 50, 121127.Google Scholar
Tellegen, A and Briggs, PF (1967) Old wine in new skins: grouping Wechsler subtests into new scales. Journal of Consulting Psychology 31, 499506.Google Scholar
Thierry, AM, Tassin, JP, Blanc, G and Glowinski, J (1976) Selective activation of mesocortical DA system by stress. Nature 263, 242244.Google Scholar
Turner, HA, Finkelhor, D and Ormrod, R (2010) Poly-victimization in a national sample of children and youth. American Journal of Preventive Medicine 38, 323330.Google Scholar
van Nierop, M, Lataster, T, Smeets, F, Gunther, N, van Zelst, C, de Graaf, R et al. (2014 a) Psychopathological mechanisms linking childhood traumatic experiences to risk of psychotic symptoms: analysis of a large, representative population-based sample. Schizophrenia Bulletin 40(Suppl. 2), S123S130.Google Scholar
van Nierop, M, van Os, J, Gunther, N, van Zelst, C, de Graaf, R, ten Have, M et al. (2014 b) Does social defeat mediate the association between childhood trauma and psychosis? Evidence from the NEMESIS-2 study. Acta Psychiatrica Scandinavica 129, 467476.Google Scholar
van Os, J and Guloksuz, S (2017) A critique of the “ultra-high risk” and “transition” paradigm. World Psychiatry 16, 200206.Google Scholar
van Os, J, Kenis, G and Rutten, BP (2010) The environment and schizophrenia. Nature 468, 203212.Google Scholar
Varese, F, Smeets, F, Drukker, M, Lieverse, R, Lataster, T, Viechtbauer, W et al. (2012) Childhood adversities increase the risk of psychosis: a meta-analysis of patient-control, prospective- and cross-sectional cohort studies. Schizophrenia Bulletin 38, 661671.Google Scholar
Vassos, E, Pedersen, CB, Murray, RM, Collier, DA and Lewis, CM (2012) Meta-analysis of the association of urbanicity with schizophrenia. Schizophrenia Bulletin 38, 11181123.Google Scholar
Wechsler, D (2002) WISC-III: Escala de Inteligência Wechsler para Crianças: Manual. São Paulo: Casa do Psicólogo.Google Scholar
Weissman, MM, Wickramaratne, P, Adams, P, Wolk, S, Verdeli, H and Olfson, M (2000) Brief screening for family psychiatric history: the family history screen. Archives of General Psychiatry 57, 675682.Google Scholar
Supplementary material: File

Moriyama et al. supplementary material 1

Moriyama et al. supplementary material

Download Moriyama et al. supplementary material 1(File)
File 22.1 KB
Supplementary material: File

Moriyama et al. supplementary material 2

Moriyama et al. supplementary material

Download Moriyama et al. supplementary material 2(File)
File 19.5 KB
Supplementary material: File

Moriyama et al. supplementary material 3

Moriyama et al. supplementary material

Download Moriyama et al. supplementary material 3(File)
File 24.6 KB
Supplementary material: File

Moriyama et al. supplementary material 4

Moriyama et al. supplementary material

Download Moriyama et al. supplementary material 4(File)
File 24.4 KB
Supplementary material: File

Moriyama et al. supplementary material 5

Moriyama et al. supplementary material

Download Moriyama et al. supplementary material 5(File)
File 24.4 KB