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Subdividing the functional psychoses: a family hereditary approach

Published online by Cambridge University Press:  09 July 2009

Christian Scharfetter*
Affiliation:
The Psychiatrische Universitätsklinik, Zürich, Switzerland
*
1Address for correspondence: Prof. Dr Med. Christian Scharfetter, Psychiatrische Universitätsklinik, Postfach 68, CH-8029, Zurich 8, Switzerland.

Synopsis

Family genetic data, based on standardized and independent diagnostic procedures of index and secondary cases, confirmed the dichotomy between schizophrenias and affective disorders. The classical schizophrenic subtypes exhibited a significant tendency towards homotypia among their secondary cases. The genetic evidence did not support the monopolar–bipolar subdivision of affective disorder. Schizo-affective disorders impinged on the clear-cut schizophrenic and affective psychotic disorders and there was no homotypical tendency among the relatives of index cases with this diagnosis.

Type
Brief Communication
Copyright
Copyright © Cambridge University Press 1981

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References

Angst, J. (1966). Zur Aetiologie und Nosologie enclogener depressiver Psychosen. Monograph Gesamtgebiete Neurologie und Psychiatrie no. 112. Springer: Berlin.CrossRefGoogle Scholar
Angst, J., Frey, R., Lohmeyer, B. & Zerbin-Ruedin, E. (1980). Bipolar manic depressive psychoses: results of a genetic investigation. Human Genetics 55, 237254.CrossRefGoogle ScholarPubMed
Bleuler, M. (1972). Die schizophrenen Geistesstörungen im Lichte langjähriger Kranken- und Familiengeschichten. Thieme: Stuttgart.Google Scholar
Brockington, I. F. & Leff, J. P. (1979). Schizo-affective psychosis: definitions and incidence. Psychological Medicine 9, 9199.CrossRefGoogle ScholarPubMed
Garrone, G. (1962). Étude statistique et génétique de la schizophrènie à Genève de 1901–1950. Journal de génétique humaine 11, 89219.Google Scholar
Gottesmann, I. & Shields, J. (1976). A critical review of recent adoption, twin and family studies of schizophrenia: behavioural genetics perspectives. Schizophrenia Bulletin 2, 360401.CrossRefGoogle Scholar
Kallmann, F. J. (1938). The Genetics of Schizophrenia. Augustin: New York.Google Scholar
Knoll, H. (1954). Klinisch-genealogischer Beitrag zur Frage der perniziösen Katatonie. Archiv für Psychiatrie und Nervenkrankhelten 192, 133.CrossRefGoogle Scholar
Perris, C. (1966). A study of bipolar (manic-depressive) and unipolar recurrent depressive psychoses. Acta psychiatrica scandinavica (Suppl.) 194, 1189.Google Scholar
Scharfetter, C., Moerbt, H. & Wing, J. K. (1976). Diagnosis of functional psychoses. Archiv für Psychiatrie und Nervenkrankheiten 222, 6167.CrossRefGoogle ScholarPubMed
Schulz, B. (1932). Zur Erbpathologie der Schizophrenie. Zeirschrft für die gesamte Neurologie und Psychiatrie 143, 175293.CrossRefGoogle Scholar
Schwab, H. (1938). Die Katatonie auf Grund katamnestischer Untersuchungen. II. Teil: Die Erblichkeit der eigentlichen Katatonie. Zeitschrift für die gesamte Neurologie und Psychiatrie 163, 441506.CrossRefGoogle Scholar
Slater, E. (1938). Zur Erbpathologie des manisch-depressiven Irreseins. Die Eltern und Kinder von Manisch-Depressiven. Zeitschrift für die gesamte Neurologie und Psychiatrie 163, 147.CrossRefGoogle Scholar
Slater, E. (1947). Genetical causes of schizophrenic symptoms. Monatsschrift für Psychiatrie und Neurologie 133, 5058.CrossRefGoogle Scholar
Slater, E. (1953). Genetic investigations in twins. Journal of Mental Science 99, 4452.CrossRefGoogle ScholarPubMed
Strömgren, E. (1935). Zum Ersatz des Weinbergschen ‘abgekürzten Verfahrens’. Zugleich ein Beitrag zur Frage von der Erblichkeit des Erkrankungsalters bei der Schizoprenie. Zentralblatt für die gesamte Neurologie und Psychiatrie 153, 784797.CrossRefGoogle Scholar
Taylor, M. A., Abrams, R. & Hayman, M. A. (1980). The classification of affective disorders – a reassessment of the bipolar–unipolar dichotomy. Journal of Affective Disorders 2, 95109.CrossRefGoogle ScholarPubMed
Wing, J. K., Cooper, J. E. & Sartorius, N. (1974). The Measurement and Classification of Psychiatric Symptoms. Cambridge University Press: Cambridge.Google Scholar