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Leading indicators of community-based violent events among adults with mental illness

Published online by Cambridge University Press:  21 December 2016

R. A. Van Dorn ,
K. J. Grimm ,
S. L. Desmarais ,
S. J. Tueller ,
K. L. Johnson  and
M. S. Swartz
R. A. Van Dorn*
Affiliation:
Behavioral and Urban Health Program, RTI International, Research Triangle Park, NC, USA
K. J. Grimm
Affiliation:
Department of Psychology, Arizona State University, Tempe, AZ, USA
S. L. Desmarais
Affiliation:
Department of Psychology, North Carolina State University, Raleigh, NC, USA
S. J. Tueller
Affiliation:
Behavioral and Urban Health Program, RTI International, Research Triangle Park, NC, USA
K. L. Johnson
Affiliation:
Behavioral and Urban Health Program, RTI International, Research Triangle Park, NC, USA
M. S. Swartz
Affiliation:
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA
*
*Address for correspondence: R. A. Van Dorn, Ph.D., RTI International, 3040 E. Cornwallis Road, PO Box 12194, Research Triangle Park, NC 27709, USA. (Email: [email protected])
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Abstract

Background

The public health, public safety and clinical implications of violent events among adults with mental illness are significant; however, the causes and consequences of violence and victimization among adults with mental illness are complex and not well understood, which limits the effectiveness of clinical interventions and risk management strategies. This study examined interrelationships between violence, victimization, psychiatric symptoms, substance use, homelessness and in-patient treatment over time.

Method

Available data were integrated from four longitudinal studies of adults with mental illness. Assessments took place at baseline, and at 1, 3, 6, 9, 12, 15, 18, 24, 30 and 36 months, depending on the parent studies’ protocol. Data were analysed with the autoregressive cross-lag model.

Results

Violence and victimization were leading indicators of each other and affective symptoms were a leading indicator of both. Drug and alcohol use were leading indicators of violence and victimization, respectively. All psychiatric symptom clusters – affective, positive, negative, disorganized cognitive processing – increased the likelihood of experiencing at least one subsequent symptom cluster. Sensitivity analyses identified few group-based differences in the magnitude of effects in this heterogeneous sample.

Conclusions

Violent events demonstrated unique and shared indicators and consequences over time. Findings indicate mechanisms for reducing violent events, including trauma-informed therapy, targeting internalizing and externalizing affective symptoms with cognitive–behavioral and psychopharmacological interventions, and integrating substance use and psychiatric care. Finally, mental illness and violence and victimization research should move beyond demonstrating concomitant relationships and instead focus on lagged effects with improved spatio-temporal contiguity.

Keywords

Autoregressive cross-laglongitudinal studiesmental illnessvictimizationviolence.
Type
Original Articles
Information
Psychological Medicine , Volume 47 , Issue 7 , May 2017 , pp. 1179 - 1191
Copyright
Copyright © Cambridge University Press 2016 

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References

Citrome, L, Volavka, J (1997). Psychopharmacology of violence: Part II: beyond the acute episode. Psychiatric Annals 27, 696–703.CrossRefGoogle Scholar
Citrome, L, Volavka, J, Czobor, P, Sheitman, B, Lindenmayer, J-P, McEvoy, J, Cooper, TB, Chakos, M, Lieberman, JA (2001). Effects of clozapine, olanzapine, risperidone, and haloperidol on hostility among patients with schizophrenia. Psychiatric Services 52, 1510–1514.CrossRefGoogle ScholarPubMed
Coid, JW, Kallis, C, Doyle, M, Shaw, J, Ullrich, S (2015). Identifying causal risk factors for violence among discharged patients. PLOS ONE 10, e0142493.CrossRefGoogle ScholarPubMed
Curran, PJ, Hussong, AM (2009). Integrative data analysis: the simultaneous analysis of multiple data sets. Psychological Methods 14, 81–100.Google Scholar
Cuthbert, BN, Insel, TR (2010). Toward new approaches to psychotic disorders: the NIMH Research Domain Criteria project. Schizophrenia Bulletin 36, 1061–1062.CrossRefGoogle ScholarPubMed
Dack, C, Ross, J, Papadopoulos, C, Stewart, D, Bowers, L (2013). A review and meta-analysis of the patient factors associated with psychiatric in-patient aggression. Acta Psychiatrica Scandinavica 127, 255–268.CrossRefGoogle ScholarPubMed
Denson, TF (2015). Four promising psychological interventions for reducing reactive aggression. Current Opinion in Behavioral Sciences 3, 136–141.Google Scholar
Desmarais, SL, Van Dorn, RA, Johnson, KL, Grimm, KJ, Douglas, KS, Swartz, MS (2014). Community violence perpetration and victimization among adults with mental illnesses. American Journal of Public Health 104, 2342–2349.CrossRefGoogle ScholarPubMed
Drake, RE, Osher, FC, Noordsy, DL, Hurlbut, SC, Teague, GB, Beaudett, MS (1990). Diagnosis of alcohol use disorders in schizophrenia. Schizophrenia Bulletin 16, 57–67.CrossRefGoogle ScholarPubMed
Fazel, S, Långström, N, Hjern, A, Grann, M, Lichtenstein, P (2009). Schizophrenia, substance abuse, and violent crime. JAMA 301, 2016–2023.CrossRefGoogle ScholarPubMed
First, MB, Spitzer, RL, Gibbon, M, Williams, JBW (1996). Structured Clinical Interview for Axes I and II DSM-IV Disorders-Patient Edition (SCID-I/P). Biometrics Research Department, New York State Psychiatric Institute: New York.Google Scholar
Glass, GV (1976). Primary, secondary, and meta-analysis. Educational Researcher 5, 3–8.Google Scholar
Glickman, ME, Rao, SR, Schultz, MR (2014). False discovery rate control is a recommended alternative to Bonferroni-type adjustments in health studies. Journal of Clinical Epidemiology 67, 850–857.CrossRefGoogle ScholarPubMed
Goldman-Rakic, PS (1994). Working memory dysfunction in schizophrenia. Journal of Neuropsychiatry and Clinical Neurosciences 6, 348–357.Google Scholar
Grimm, KJ, Ram, N (2009). Nonlinear growth models in M plus and SAS. Structural Equation Modeling 16, 676–701.CrossRefGoogle Scholar
Grubaugh, AL, Zinzow, HM, Paul, L, Egede, LE, Frueh, BC (2011). Trauma exposure and posttraumatic stress disorder in adults with severe mental illness: a critical review. Clinical Psychology Review 31, 883–899.CrossRefGoogle ScholarPubMed
Kay, SR, Flszbein, A, Opfer, LA (1987). The Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Schizophrenia Bulletin 13, 261–276.Google Scholar
Kraemer, HC, Kazdin, AE, Offord, DR, Kessler, RC, Jensen, PS, Kupfer, DJ (1997). Coming to terms with the terms of risk. Archives of General Psychiatry 54, 337–343.Google Scholar
Lieberman, JA, Stroup, TS, McEvoy, JP, Swartz, MS, Rosenheck, RA, Perkins, DO, Keefe, RS, Davis, SM, Davis, CE, Lebowitz, BD (2005). Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. New England Journal of Medicine 353, 1209–1223.Google Scholar
Lindenmayer, J-P, Liu-Seifert, H, Kulkarni, PM, Kinon, BJ, Stauffer, V, Edwards, SE, Chen, L, Adams, DH, Ascher-Svanum, H, Buckley, PF (2009). Medication nonadherence and treatment outcome in patients with schizophrenia or schizoaffective disorder with suboptimal prior response. Journal of Clinical Psychiatry 70, 990–996.Google Scholar
Mayfield, D, McLeod, G, Hall, P (1974). The CAGE questionnaire: validation of a new alcoholism screening instrument. American Journal of Psychiatry 131, 1121–1123.Google Scholar
McArdle, JJ (1994). Structural factor analysis experiments with incomplete data. Multivariate Behavioral Research 29, 409–454.Google Scholar
Michie, C, Cooke, DJ (2006). The structure of violent behavior a hierarchical model. Criminal Justice and Behavior 33, 706–737.CrossRefGoogle Scholar
Moberg, T, Nordström, P, Forslund, K, Kristiansson, M, Åsberg, M, Jokinen, J (2011). CSF 5-HIAA and exposure to and expression of interpersonal violence in suicide attempters. Journal of Affective Disorders 132, 173–178.Google Scholar
Monahan, J, Redlich, AD, Swanson, J, Robbins, PC, Appelbaum, PS, Petrila, J, Steadman, HJ, Swartz, M, Angell, B, McNiel, DE (2005). Use of leverage to improve adherence to psychiatric treatment in the community. Psychiatric Services 56, 37–44.CrossRefGoogle ScholarPubMed
Nestor, PG (2014). Mental disorder and violence: personality dimensions and clinical features. American Journal of Psychiatry 159, 1973–1978.Google Scholar
Nolan, KA, Volavka, J, Czobor, P, Sheitman, B, Lindenmayer, J-P, Citrome, LL, McEvoy, J, Lieberman, JA (2005). Aggression and psychopathology in treatment-resistant inpatients with schizophrenia and schizoaffective disorder. Journal of Psychiatric Research 39, 109–115.Google Scholar
Odgers, CL, Mulvey, EP, Skeem, JL, Gardner, W, Lidz, CW, Schubert, C (2009). Capturing the ebb and flow of psychiatric symptoms with dynamical systems models. American Journal of Psychiatry 166, 575–582.Google Scholar
Overall, JE (1974). The Brief Psychiatric Rating Scale in psychopharmacology research. In Psychological Measurements in Psychopharmacology (ed. Olivier-Martin, R), pp. 67–78. Karger: Oxford.Google Scholar
Oxman, AD, Clarke, MJ, Stewart, LA (1995). From science to practice: meta-analyses using individual patient data are needed. JAMA 274, 845–846.Google Scholar
Peduzzi, P, Concato, J, Kemper, E, Holford, TR, Feinstein, AR (1996). A simulation study of the number of events per variable in logistic regression analysis. Journal of Clinical Epidemiology 49, 1373–1379.Google Scholar
Pescosolido, BA, Monahan, J, Link, BG, Stueve, A, Kikuzawa, S (1999). The public's view of the competence, dangerousness, and need for legal coercion of persons with mental health problems. American Journal of Public Health 89, 1339–1345.CrossRefGoogle ScholarPubMed
Rhemtulla, M, Brosseau-Liard, PE, Savalei, V (2012). When can categorical variables be treated as continuous? A comparison of robust continuous and categorical SEM estimation methods under suboptimal conditions. Psychological Methods 17, 354–373.Google Scholar
Scheller-Gilkey, G, Moynes, K, Cooper, I, Kant, C, Miller, AH (2004). Early life stress and PTSD symptoms in patients with comorbid schizophrenia and substance abuse. Schizophrenia Research 69, 167–174.Google Scholar
Silver, E, Piquero, AR, Jennings, WG, Piquero, NL, Leiber, M (2011). Assessing the violent offending and violent victimization overlap among discharged psychiatric patients. Law and Human Behavior 35, 49–59.Google Scholar
Singh, MM, Kay, SR (1975). A comparative study of haloperidol and chlorpromazine in terms of clinical effects and therapeutic reversal with benztropine in schizophrenia. Theoretical implications for potency differences among neuroleptics. Psychopharmacologia 43, 103–113.CrossRefGoogle ScholarPubMed
Skeem, JL, Schubert, C, Odgers, C, Mulvey, EP, Gardner, W, Lidz, C (2006). Psychiatric symptoms and community violence among high-risk patients: a test of the relationship at the weekly level. Journal of Consulting and Clinical Psychology 74, 967–979.Google Scholar
Smith, ML, Glass, GV (1977). Meta-analysis of psychotherapy outcome studies. American Psychologist 32, 752–760.CrossRefGoogle Scholar
Steadman, HJ, Mulvey, EP, Monahan, J, Robbins, PC, Appelbaum, PS, Grisso, T, Roth, LH, Silver, E (1998). Violence by people discharged from acute psychiatric inpatient facilities and by others in the same neighborhoods. Archives of General Psychiatry 55, 393–401.Google Scholar
Swanson, J, Swartz, M, Elbogen, E, Van Dorn, R, Ferron, J, Wagner, H, McCauley, B, Kim, M (2006 a). Facilitated psychiatric advance directives: a randomized trial of an intervention to foster advance treatment planning among persons with severe mental illness. American Journal of Psychiatry 163, 1943–1951.Google Scholar
Swanson, JW, Swartz, MS, Elbogen, EB (2004). Effectiveness of atypical antipsychotic medications in reducing violent behavior among persons with schizophrenia in community-based treatment. Schizophrenia Bulletin 30, 3–20.Google Scholar
Swanson, JW, Swartz, MS, Van Dorn, RA, Elbogen, EB, Wagner, HR, Rosenheck, RA, Stroup, TS, McEvoy, JP, Lieberman, JA (2006 b). A national study of violent behavior in persons with schizophrenia. Archives of General Psychiatry 63, 490–499.Google Scholar
Swanson, JW, Swartz, MS, Van Dorn, RA, Volavka, J, Monahan, J, Stroup, TS, McEvoy, JP, Wagner, HR, Elbogen, EB, Lieberman, JA (2008). Comparison of antipsychotic medication effects on reducing violence in people with schizophrenia. British Journal of Psychiatry 193, 37–43.Google Scholar
Tueller, SJ, Johnson, KL, Grimm, KJ, Desmarais, SL, Sellers, BG, Van Dorn, RA (2016). Effects of sample size and distributional assumptions on competing models of the factor structure of the PANSS and BPRS. International Journal of Methods in Psychiatric Research. Published online 2 December 2016. doi:10.1002/mpr.1549.Google Scholar
Van Dorn, R, Volavka, J, Johnson, N (2012). Mental disorder and violence: is there a relationship beyond substance use? Social Psychiatry and Psychiatric Epidemiology 47, 487–503.Google Scholar
Van Dorn, RA, Desmarais, SL, Grimm, KJ, Tueller, SJ, Johnson, KL, Sellers, BG, Swartz, MS (2016). The latent structure of psychiatric symptoms across mental disorders as measured with the PANSS and BPRS. Psychiatry Research 245, 83–90.Google Scholar
Virkkunen, M, Linnoila, M (1990). Serotonin in early onset, male alcoholics with violent behaviour. Annals of Medicine 22, 327–331.CrossRefGoogle ScholarPubMed
Virkkunen, M, Nuutila, A, Goodwin, FK, Linnoila, M (1987). Cerebrospinal fluid monoamine metabolite levels in male arsonists. Archives of General Psychiatry 44, 241–247.CrossRefGoogle ScholarPubMed
Volavka, J (1999). The neurobiology of violence: an update. Journal of Neuropsychiatry and Clinical Neurosciences 11, 307–314.Google Scholar
Volavka, J (2008). Neurobiology of Violence. American Psychiatric Publishing, Inc.: Washington, DC.Google Scholar
Volavka, J, Czobor, P, Citrome, L, Van Dorn, RA (2014). Effectiveness of antipsychotic drugs against hostility in patients with schizophrenia in the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) study. CNS Spectrums 19, 374–381.CrossRefGoogle ScholarPubMed
Witt, K, Van Dorn, R, Fazel, S (2013). Risk factors for violence in psychosis: systematic review and meta-regression analysis of 110 studies. PLOS ONE 8, e55942.Google Scholar
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