Published online by Cambridge University Press: 15 September 2014
1. Degeneration of the germinal epithelium of the testis invariably follows the operation of vasoligation or of vasectomy in the mouse, but does not become evident until a considerable period of time has elapsed.
2. Similar degeneration follows the operation of epididymo-deferentectomy, but after a much shorter interval of time.
3. This degeneration is caused perhaps by the pressure within the seminiferous tubules exerted by the accumulation of seminal products, or more probably by the action of toxic substances liberated from the disintegrating cell and sperm debris.