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The application of monoclonal antibodies to the typing and isolation of lymphoreticular cells

Published online by Cambridge University Press:  05 December 2011

Peter C. L. Beverley
Peter C. L. Beverley
Affiliation:
I.C.R.F. Human Tumour Immunology Group, School of Medicine, University College London, Faculty of Clinical Sciences, University Street, London WC1E 6JJ
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Synopsis

We have analysed the specificity of monoclonal antibodies to human leucocyte subsets by three methods. The distribution of antigen bearing cells has been studied in frozen tissue sections of lymphoid and other tissues by immunofluorescence or immunoenzymatic methods. The cellular distribution of antigen has been compared with existing well established markers and the function of antigen bearing cells has been studied by separation and assay in in vitro model systems. Antibodies characterised in this way may yield useful information when applied to clinical problems.

Type
Research Article
Information
Proceedings of the Royal Society of Edinburgh, Section B: Biological Sciences , Volume 81 , Issue 4: Clinical applications of monoclonal antibodies , 1982 , pp. 221 - 232
Copyright
Copyright © Royal Society of Edinburgh 1982

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