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meeting-report

LIPGENE: an integrated approach to tackling the metabolic syndrome

Published online by Cambridge University Press:  07 March 2007

Judith Buttriss  and
Anne Nugent
Judith Buttriss*
Affiliation:
British Nutrition Foundation, 52–54 High Holborn, London, WC1V 6RQ, UK
Anne Nugent
Affiliation:
British Nutrition Foundation, 52–54 High Holborn, London, WC1V 6RQ, UK
*
†Corresponding author: Dr Judith Buttriss, fax +44 207 404 6747, [email protected]
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Abstract

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The prevalence of obesity, overweight and type 2 diabetes are increasing in all regions of Europe. Obesity is already commonplace, affecting 10–20% of men and 10–25% of women, and by 2010 approximately 31 million of the population will require treatment for diabetes and its related complications, including the ‘metabolic syndrome’ (a cluster of cardiovascular risk factors). Associated health and social welfare costs are expected to rise to economically unsustainable levels in Europe as a direct result of these trends. Effective strategies are needed to tackle this major public health problem and to decrease dependence on medical management. These issues are the focus of LIPGENE (FOOD-CT-2003-505944), funded by the European Commission, which will investigate the interactions between dietary constituents and the genome in the development of chronic diseases, such as the metabolic syndrome, and will utilise new technologies to identify novel solutions. The LIPGENE consortium comprises twenty-five research centres across Europe. Features of the 5-year work programme include a major human nutrition intervention study in eight European cities, development of a sustainable vegetable oil product naturally rich in long-chain n-3 fatty acids, and identification of a protocol for feeding dairy cows that will result in milk with a more favourable fatty acid composition. Other work packages will provide a detailed economic analysis of the current and future healthcare costs associated with the metabolic syndrome, and an analysis of consumer attitudes. There is also a dissemination programme associated with the project that features conferences, workshops and associated publications.

Keywords

LIPGENEObesityMetabolic syndromeDiabetesGenetic variation
Type
Conference on ‘The ticking time bomb: the metabolic syndrome’
Information
Proceedings of the Nutrition Society , Volume 64 , Issue 3 , August 2005 , pp. 345 - 347
Copyright
Copyright © The Nutrition Society 2005

References

Buttriss, J (2003) Metabolic syndrome: new research underway. Nutrition Bulletin 28, 381–385.CrossRefGoogle Scholar
Eurostat (2000) Elderly statistics in Europe. www.europa.eu.int/comm/eurostat. Google Scholar
Fry, J & Finley, W (2005) The prevalence and costs of obesity in the EU. Proceedings of the Nutrition Society 64, 359–362.CrossRefGoogle ScholarPubMed
Givens, DI (2005) The role of animal nutrition in improving the nutritive value of animal-derived foods in relation to chronic disease. Proceedings of the Nutrition Society 64, 395–402.CrossRefGoogle ScholarPubMed
Goldberg, G (2003) Obesity: FLAIR FLOW 4 Synthesis Report. Health Professionals no. 3. Paris: INRA.Google Scholar
Isomaa, B (2003) A major health hazard: the metabolic syndrome. Life Sciences 73, 2395–2411.CrossRefGoogle Scholar
Knowler, WC, Barrett-Connor, E, Fowler, SE, Hamman, RF, Lachin, JM, Walker, EA & Nathan, DM (2002) Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. New England Journal of Medicine 346, 393–403.Google ScholarPubMed
Mann, JI (2002) Diet and risk of coronary heart disease and type 2 diabetes. Lancet 360, 783–789.CrossRefGoogle ScholarPubMed
Mokdad, AH, Serdula, MK, Dietz, WH, Bowman, BA, Marks, JS & Koplan, JP (2000) The continuing epidemic of obesity in the United States. Journal of the American Medical Association 284, 1650–1651.CrossRefGoogle ScholarPubMed
Napier, JA & Sayanova, O (2005) The production of very long chain polyunsaturated fatty acid biosynthesis in transgenic plants: towards a sustainable source of fish oils. Proceedings of the Nutrition Society 64, 387–393.CrossRefGoogle ScholarPubMed
Pomerleau, J, Pudule, I, Grinberga, D, Kadziauskiene, K, Abaravicius, A, Bartkeviciute, R, Vaask, S, Robertson, A & McKee, M (2000) Patterns of body weight in the Baltic Republics. Public Health Nutrition 3, 3–10.CrossRefGoogle ScholarPubMed
Roche, HM, Phillips, C & Gibney, MJ (2005) The metabolic syndrome: the crossroads of diet and genetics. Proceedings of the Nutrition Society 64, 371–377.CrossRefGoogle ScholarPubMed
Shaw, DI, Hall, WL & Williams, CM (2005) Metabolic syndrome: what is it and what are the implications. Proceedings of the Nutrition Society 64, 349–357.CrossRefGoogle ScholarPubMed
Stewart-Knox, B (2005) Psychological underpinnings of metabolic syndrome. Proceedings of the Nutrition Society 64, 363–369.CrossRefGoogle ScholarPubMed
Upritchard, JE, Zeelenberg, MJ, Huizinga, H, Verschuren, PM & Trautwein, EA (2005) Modern fat technology: what is the potential for heart health. Proceedings of the Nutrition Society 64, 379–386.CrossRefGoogle ScholarPubMed
World Bank Atlas (2000) Data and statistics. www.worldbank.org Google Scholar
Zimmet, P, Alberti, KG & Shaw, J (2001) Global and societal implications of the diabetes epidemic. Nature 414, 782–787.CrossRefGoogle ScholarPubMed