Low vitamin D status is a common public health issue for pregnant women. The available evidence showed that low vitamin D dietary intake during pregnancy has been positively associated with vitamin D deficiency and seems to be one of the risk factors.(Reference Bardosono1,Reference Woon2) . The aim of this study was to identify the relationship between vitamin D intake and serum 25-hydroxyvitamin D (25(OH)D) concentration in Minangkabau pregnant women, Indonesia.
This prospective Vitamin D Pregnant Mothers (VDPM) cohort study was conducted from January to March 2018 in each public health centers in eight districts in West Sumatra province. We recruited among 323 pregnant women.(Reference Aji3,Reference Aji4) Serum 25(OH)D concentration and vitamin D intake were collected during the third trimester of pregnancy. Semi-Quantitative Food Frequency Questionnaire (SQ-FFQ) was used to assess vitamin D intake and 25(OH)D concentration was measured by enzyme-linked immunosorbent assays (ELISA). Pearson partial correlation and linear regression of those variables were calculated. Potential confounder variables such as maternal age, socio-economic status, and gestational age at blood withdrawal were adjusted in the model.
Mean of both vitamin D intake levels and 25(OH)D concentration were below recommendation, 8.47 ± 6.09 mcg/day and 24.35 ± 11.46 ng/ml, respectively. Vitamin D intake was weakly correlated with serum 25(OH)D concentration (r = 0.417, P = 0.045). Vitamin D status was not associated with vitamin D intake levels after adjusted potential confounders (P = 0.410).
Dietary vitamin D and serum 25(OH)D levels were positively but weakly correlated. Our results support the need for strategies to improve eating vitamin D-rich foods pattern to meet the recommendation dietary intake requirements and reduce the high prevalence of vitamin D deficiency status. Further studies were required to confirm these findings.