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Parenteral nutrition in the critically-ill patient: more harm than good?

Published online by Cambridge University Press:  28 February 2007

D. K. Heyland
D. K. Heyland
Affiliation:
Department of Medicine and Department of Community Health and Epidemiology, Queen's University Faculty of Health Sciences, Kingston, Ontario K7L 2V7, Canada
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Abstract

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While many studies have reported that providing parenteral nutrition (PN) can change nutritional outcomes, there are limited data that demonstrate that PN influences clinically-important end points in critically-ill patients. The purpose of the present paper is to systematically review and critically appraise the literature to examine the relationship between PN and morbidity and mortality in the critically-ill patient. Studies comparing enteral nutrition (EN) with PN and studies comparing PN with no PN were reviewed. The results suggest that EN is associated with reduced infectious complications in some critically-ill subgroups. PN, on the other hand, is associated with increased morbidity and mortality in critically-ill patients. When nutritional support is indicated, EN should be used preferentially over PN. Further studies are needed to define the optimal timing and composition of PN in patients not tolerating sufficient EN. Strategies to optimize EN delivery and minimize PN utilization in critically-ill patients are indicated.

Keywords

Parenteral nutritionEnteral nutritionCritically-ill
Type
Meeting Report
Information
Proceedings of the Nutrition Society , Volume 59 , Issue 3 , August 2000 , pp. 457 - 466
Copyright
Copyright © The Nutrition Society 2000

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