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Nuclear transcription factors: new opportunities for lipid lowering

Published online by Cambridge University Press:  28 February 2007

Bart Staels
Affiliation:
U.325 INSERM, Département d'Athérosclérose, Institut Pasteur de Lille and Faculté de Pharmacie, Université de Lille 11, BP 245, 59019 Lille, France
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Abstract

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Type
Meeting Report
Copyright
Copyright © The Nutrition Society 2000

References

Auwerx, J, Schoonjans, K, Fruchart, J-C & Staels, B (1997) Regulation of triglyceride metabolism by PPARs: fibrates and thiazolidinediones have distinct effects. Journal of Atherosclerosis and Thrombosis 3, 8189.CrossRefGoogle Scholar
Fruchart, J-C, Duriez, P & Staels, B (1999) PPARs and atherosclerosis. Current Opinion in Lipidology 10, 245257.CrossRefGoogle ScholarPubMed
Martin, G, Schoonjans, K, Staels, B & Auwerx, J (1998) PPARa activators improve glucose homeostasis by stimulating fatty acid uptake in adipocytes. Atherosclerosis 137, S75-S80.CrossRefGoogle Scholar
Pineda, Torra I, Gervois, P & Staels, B (1999) PPARa in metabolic disease, inflammation, atherosclerosis and aging. Current Opinion in Lipidology 10, 151159.Google Scholar
Schoonjans, K, Staels, B & Auwerx, J (1996a) The peroxisome proliferator activated receptors (PPARs) and their effects on lipid metabolism and adipocyte differentiation. Biochimica et Biophysica Acta 1302, 93109.CrossRefGoogle ScholarPubMed
Schoonjans, K, Staels, B & Auwerx, J (1996b) Role of the peroxisome proliferator activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression. Journal of Lipid Research 37, 907925.CrossRefGoogle ScholarPubMed
Schoonjans, K, Martin, G, Staels, B & Auwerx, J (1997) Peroxisome proliferator activated receptors orphans, with ligands and functions. Current Opinion in Lipidology 8, 159166.CrossRefGoogle ScholarPubMed
Staels, B & Auwerx, J (1998) Regulation of apoA-I gene expression by fibrates. Atherosclerosis 137, S19-S23.CrossRefGoogle ScholarPubMed
Staels, B, Dallongeville, J, Auwerx, J, Schoonjans, K, Leitersdorf, E & Fruchart, JC (1998) The mechanism of action of fibrates on lipid and lipoprotein metabolism. Circulation 98, 20882093.CrossRefGoogle ScholarPubMed