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The management of short-term intestinal failure in obese patients*

Published online by Cambridge University Press:  07 March 2007

Jeremy Powell-Tuck*
Affiliation:
St Bartholomew's and the Royal London Hospital Medical College, Queen Mary University of London, Turner Street, London E1 2AD, UK
*
Corresponding author: Professor Jeremy Powell-Tuck, fax +44 020 7375 2103, email [email protected]
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Abstract

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The prevalence of obesity in the general population is high and it is inevitable that artificial feeding will be needed from time to time in the obese patient, particularly in the critical care setting. Against a background of generous endogenous stores of energy as adipose tissue and the ability of obese individuals to survive starvation longer than non-obese individuals, emphasis is placed on preserving lean body mass and optimizing physiological function. Insulin resistance is typical of the obese individual and is exacerbated by stress; overfeeding is dangerous, particularly if it results in hyperglycaemia. Refeeding syndrome also has to be avoided. Weight may be difficult to measure and lean body mass difficult to assess. Calculation of energy requirements is therefore problematic in practice in the obese individual and there is substantial evidence from controlled clinical trials of the safety of feeding at or below resting energy expenditure. If this approach is taken it is wise to provide a more generous than normal protein intake and to beware of patients with a very high baseline urinary N excretion.

Type
BAPEN Symposium 1: Malnutrition in obesity
Copyright
Copyright © The Nutrition Society 2005

Footnotes

*

Others papers presented at this meeting have been published in Proceedings of the Nutrition Society (2004), 63.

References

American Society for Parenteral and Enteral Nutrition. 2002. Guidelines for the use of parenteral and enteral nutrition in adult and pediatric patients. Journal of Parenteral and Enteral Nutrition 26, Suppl. 2, 1SA138SA.Google Scholar
Anonymous (1997) Lactic acidosis traced to thiamine deficiency related to nationwide shortage of multivitamins for total parenteral nutrition – United States. 1997. Morbidity and Mortality Weekly Report 46, 523528.Google Scholar
Barak, N, Wall-Alonso, E & Sitrin, MD (2002) Evaluation of stress factors and body weight adjustments currently used to estimate energy expenditure in hospitalized patients. Journal of Parenteral and Enteral Nutrition 26, 231238.Google Scholar
Burge, JC, Goon, A, Choban, PS & Flancbaum, L (1994) Efficacy of hypocaloric total parenteral nutrition in hospitalized obese patients: a prospective, double-blind randomized trial. Journal of Parenteral and Enteral Nutrition 18, 203207.CrossRefGoogle ScholarPubMed
Choban, PS, Burge, JC, Scales, D & Flancbaum, L (1997) Hypoenergetic nutrition support in hospitalized obese patients: a simplified method for clinical application. American Journal of Clinical Nutrition 66, 546550.Google Scholar
Colley, CM, Fleck, A & Howard, JP (1985) Pocket computer: a new aid to nutritional support. British Medical Journal 290, 14031406.CrossRefGoogle ScholarPubMed
Corry, DB & Tuck, ML (2001) Selective aspects of the insulin resistance syndrome. Current Opinion in Nephrology and Hypertension 10, 507514.Google Scholar
Dickerson, RN, Boschert, KJ, Kudsk, KA & Brown, RO (2002) Hypocaloric enteral tube feeding in critically ill obese patients. Nutrition 18, 241246.Google Scholar
Dickerson, RN, Rosato, EF & Mullen, JL (1986) Net protein anabolism with hypocaloric parenteral nutrition in obese stressed patients. American Journal of Clinical Nutrition 44, 747755.Google Scholar
Elia, M (1990) Artificial nutritional support. Medicine International 82, 33923396.Google Scholar
Garrow, JS (2000) Composition of the body. In Human Nutrition and Dietetics, pp. 1223 [Garrow, JS, James, WPT and Ralph, A, editors] Edinburgh: Churchill LivingstoneGoogle Scholar
Glynn, CC, Greene, GW, Winkler, MF & Albina, JE (1999) Predictive versus measured energy expenditure using limits-of-agreement analysis in hospitalized, obese patients. Journal of Parenteral and Enteral Nutrition 23, 147154.CrossRefGoogle ScholarPubMed
Greenberg, GR & Jeejeebhoy, KN (1979) Intravenous protein-sparing therapy in patients with gastrointestinal disease. Journal of Parenteral and Enteral Nutrition 3, 427432.Google Scholar
Guenst, JM & Nelson, LD (1994) Predictors of total parenteral nutrition-induced lipogenesis. Chest 105, 553559.CrossRefGoogle ScholarPubMed
Hamwi, GJ (1994) Therapy: changing dietary concepts Diabetes Mellitus: Diagnosis and Management, pp. 7378 [Danowski, TS, editors] New York: American Diabetes AssociationGoogle Scholar
Harris, JA & Benedict, FG (1919) A Biometric Study of Basal Metabolism in Man. Publication no. 279. Washington, DC: Carnegie InstituteGoogle Scholar
Hearing, SD (2004) Refeeding syndrome. British Medical Journal 328, 908909.CrossRefGoogle ScholarPubMed
Horgan, GW & Stubbs, J (2003) Predicting basal metabolic rate in the obese is difficult. European Journal of Clinical Nutrition 57, 335340.Google Scholar
Jeevanandam, M, Young, DH & Schiller, WR (1991) Obesity and the metabolic response to severe multiple trauma in man. Journal of Clinical Investigation 87, 262269.CrossRefGoogle ScholarPubMed
McCowen, KC, Friel, C, Sternberg, J, Chan, S, Forse, RA, Burke, PA & Bistrian, BR (2000) Hypocaloric total parenteral nutrition: effectivenesss in prevention of hyperglycaemia and infectious complications – a randomized clinical trial. Critical Care Medicine 28, 36063611.Google Scholar
Mizock, B (1995) Alterations in carbohydrate metabolism during stress: a review of the literature. American Journal of Medicine 98, 7584.Google Scholar
Nilsson, M, Johnsen, R, Ye, W, Hveem, K & Lagergren, J (2003) Obesity and estrogen as risk factors for gastroesophageal reflux symptoms. Journal of the American Medical Association 290, 6672.Google Scholar
Sarr, MG (1999) Appropriate use, complications and advantages demonstrated in 500 consecutive needle catheter jejunostomies. British Journal of Surgery 86, 557561.CrossRefGoogle ScholarPubMed
Schofield, WN (1985) Predicting basal metabolic rate, new standards and review of previous work. Human Nutrition: Clinical Nutrition 39 Suppl. 1, 541.Google Scholar
Schunn, CD & JM, Daly (1995) Small bowel necrosis associated with postoperative jejunal tube feeding. Journal of the American College of Surgeons 180, 410416.Google Scholar
van den Berghe, G, Wouters, P, Weekers, F, Verwaest, C, Bruyninckx, F, Schetz, M, Vlasselaers, D, Ferdinande, P, Lauwers, P, Bouillon, R (2001) Intensive insulin therapy in critically ill patients. New England Journal of Medicine 345, 13591367.Google Scholar
van Lanschot, JB, Feenstra, BW, Vermeij, CG & Bruining, HA (1986) Calculation versus measurement of total energy expenditure. Critical Care Medicine 14, 981985.CrossRefGoogle ScholarPubMed