Hostname: page-component-78c5997874-v9fdk Total loading time: 0 Render date: 2024-11-15T03:22:51.044Z Has data issue: false hasContentIssue false

Industrial dimensions of food allergy

Published online by Cambridge University Press:  07 March 2007

René Crevel
Affiliation:
SEAC Toxicology Laboratory, Unilever Research, Sharnbrook, Bedford MK44 1LQ, UK
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Serious attempts to estimate the impact of allergic reactions to foods on public health did not begin until the 1980s. Until about 15 years ago food allergy was considered a minor aspect of food safety. Two developments probably prompted a radical re-appraisal of that situation. The first was the apparently inexorable rise in the prevalence of atopic diseases, of which food allergy forms a part, with its possible consequences highlighted by some well-publicised severe reactions. The second was the growth of genetic modification technology, manifested by the commercialisation of transgenic crops. Each of these developments impacted on the food industry in distinct ways. On the one hand, consumers with food allergies had to be enabled to avoid specific allergens in products formulated with existing ingredients. Food manufacturers therefore had to identify those specific allergens down to trace amounts in all the ingredients forming the product and label or remove them. On the other hand, the introduction of products using ingredients from novel sources required an assessment of the allergenicity of these ingredients as an integral part of safety assurance. The approaches used by the food industry to protect existing consumers who have food allergies and those at potential risk of sensitisation from novel proteins will be illustrated, emphasising how they need to be built into every stage of the life cycle of a product.

Type
Symposium on ‘Reacting to allergy’
Copyright
Copyright © The Nutrition Society 2005

References

Aalberse, RC (2000) Structural biology of allergens. Journal of Allergy and Clinical Immunology 106, 228238 CrossRefGoogle ScholarPubMed
Arps, V, Sudowe, S & Kolsch, E (1998) Antigen dose-dependent differences in IgE antibody production are not due to polarization towards Th1 and Th2 cell subsets. European Journal of Immunology 28, 681686 3.0.CO;2-A>CrossRefGoogle Scholar
Bindslev-Jensen, C, Briggs, D & Osterballe, M (2002) Can we determine a threshold level for allergenic foods by statistical analysis of published data in the literature. Allergy 57, 741746 CrossRefGoogle Scholar
Bock, SA & Atkins, FM (1990) Patterns of food hypersensitivity during sixteen years of double-blind, placebo-controlled food challenges. Journal of Pediatrics 117, 561567 CrossRefGoogle ScholarPubMed
Breiteneder, H & Mills, ENC (2005) Molecular properties of food allergens. Journal of Allergy and Clinical Immunology 115, 1423 CrossRefGoogle ScholarPubMed
Codex Alimentarius Commission (2002) Report of the third session of the Codex ad hoc Intergovernmental Task Force on foods Derived from Biotechnology (ALINORM 03/34). ftp://ftp.fao.org/codex/alinorm03/Al03_34e.pdfGoogle Scholar
European Commission (2003) Directive 2003/89/EC of the European Parliament and of the Council of 10 November 2003 amending Directive 2000/13/EC as regards indication of the ingredients present in foodstuffs. Official Journal of the European Communities L308, 1518 Google Scholar
Food and & Agriculture Organization (1998) Food Quality and Safety Systems – A Training Manual on Food Hygiene and the Hazard Analysis and Critical Control Point (HACCP) System Rome FAOGoogle Scholar
Food and, Agriculture Organization/World & Health Organization (2001) FAO/WHO Expert Consultation on Foods Derived from Biotechnology Rome: FAOGoogle Scholar
Food Standards, AustraliaNew Zealand (2002) The Australia New Zealand Food Standards Code. http://www.foodstandards.gov.au/foodstandardscode/ Google Scholar
Foucard, T, Malmheden Yman, I (1999) A study on severe food reactions in Sweden – Is soy protein an underestimated cause of food anaphylaxis. Allergy 54, 261265 CrossRefGoogle Scholar
Kanny, G, Moneret-Vautrin, DA, Flabbee, J, Beaudouin, E, Morisset, M & Thevenin, F (2001) Population study of food allergy in France. Journal of Allergy and Clinical Immunology 108, 133140 CrossRefGoogle ScholarPubMed
Lewis, S, Butland, B, Strachan, D, Bynner, J, Richards, D, Butler, N & Britton, J (1996) Study of the aetiology of wheezing illness at age 16 in two national British birth cohorts. Thorax 51, 670676 CrossRefGoogle ScholarPubMed
Lin, W, Price, GK & Allen, E (2001) StarLink: Impacts on US corn market and world trade Feed Yearbook 46 – 54 Washington, DC Economic Research Service, USDA http://www.ers.usda.gov/Briefing/Corn/pdfs/StarLinkFDS2001.pdf Google Scholar
Loveless, MH (1950) Milk allergy: a survey of its incidence; experiments with a masked ingestion test. Journal of Allergy 21, 489 CrossRefGoogle ScholarPubMed
Metcalfe, DD, Astwood, JD, Townsend, R & Sampson, HA (1996) Assessment of the allergenic potential of foods derived from genetically engineered crop plants. Critical Reviews in Food Science and Nutrition 36, Suppl.. S165S186.CrossRefGoogle ScholarPubMed
Prausnitz, C, Küstner, H (1921) Studien über die Überempfíndlichkeit (Study of hypersensitivity). Zentralblatt für Bakteriologie Mikrobiologie und Hygiene Abteilung Originale 86, 160169 Google Scholar
Rhodes, HL, Thomas, P, Sporik, R, Holgate, ST & Cogswell, JJ (2002) A birth cohort study of subjects at risk of atopy: twenty-two-year follow-up of wheeze and atopic status. American Journal of Respiratory and Critical Care Medicine 165, 176180 CrossRefGoogle ScholarPubMed
Rogers, PR & Croft, M (1999) Peptide dose, affinity, and time of differentiation can contribute to the Th1/Th2 cytokine balance. Journal of Immunology 163, 12051213 CrossRefGoogle Scholar
Sampson, HA (2004) Update on food allergy. Journal of Allergy and Clinical Immunology 113, 805819 CrossRefGoogle ScholarPubMed
Sheikh, A & Alves, B (2000) Hospital admissions for acute anaphylaxis: time trend study. British Medical Journal 320, 1441 CrossRefGoogle ScholarPubMed
Taylor, SL, Hefle, SL, Bindslev-Jensen, C, Bock, SA, Burks, AW, Christie, L et al. (2002) Factors affecting the determination of threshold doses for allergenic foods: How much is too much. Journal of Allergy and Clinical Immunology 109, 2430 Google Scholar
Tuft, L & Blumstein, GI (1942) Studies in food allergy. II. Sensitization to fresh fruits: clinical and experimental observations. Journal of Allergy 13, 574581 CrossRefGoogle Scholar
US Congress (2004) Food Allergen Labelling and Consumer Protection Act of 2004. http://www.cfsan.fda.gov/~dms/alrgact.html Google Scholar
Wagner, S & Breiteneder, H (2002) The latex-fruit syndrome. Biochemical Society Transactions 30, 935940 CrossRefGoogle ScholarPubMed
Young, E, Stoneham, MD, Petruckevitch, A, Barton, J & Rona, R (1994) A population study of food intolerance. Lancet i, 11271130 CrossRefGoogle Scholar