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Food-based berry intervention studies and blood pressure: a systematic review of randomised controlled trials

Published online by Cambridge University Press:  11 September 2015

C. Heneghan ,
J. Lyons ,
A. Lucey  and
M. Kiely
C. Heneghan
Affiliation:
Vitamin D Research Group, School of Food and Nutritional Sciences, University College Cork, Republic of Ireland
J. Lyons
Affiliation:
Vitamin D Research Group, School of Food and Nutritional Sciences, University College Cork, Republic of Ireland
A. Lucey
Affiliation:
Vitamin D Research Group, School of Food and Nutritional Sciences, University College Cork, Republic of Ireland
M. Kiely
Affiliation:
Vitamin D Research Group, School of Food and Nutritional Sciences, University College Cork, Republic of Ireland
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Abstract

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Information
Proceedings of the Nutrition Society , Volume 74 , Issue OCE4: Irish Section Meeting, 17–19 June 2015, Nutrition at key life stages: new findings, new approaches , 2015 , E227
Copyright
Copyright © The Authors 2015 

Berries are a rich source of polyphenols, which may contribute to the prevention of cardiovascular disease (CVD) through effects on blood pressure, lipid profile and vascular endothelial functionReference Basu, Rhone and Lyons 1 . The aim of this review was to evaluate the health effects of berry consumption reported in randomised controlled trials (RCTs). Key terms associated with berry types, cardiovascular outcomes and human intervention studies of at least 2 weeks duration were combined and searched within the PubMed and Web of Science databases (from their inception until January 2015). A total of 1219 articles met the inclusion criteria. After removal of duplicates in EndNote, abstracts or full text articles (n 1090) were independently assessed by two researchers for suitability. Excluded articles were mainly studies that did not include the exposure or outcome of interest (n 1041), irrelevant (n 24) or conducted in animal (n 8) or in vitro (n 9) models. Eight RCTs that investigated the effects of berry consumption on blood pressure among adults were included.

Systolic blood pressure (SBP), diastolic blood pressure (DBP) Low dose (LD), high dose (HD);

aSBP(140–159 mmHg), DBP (90–99 mmHg).

Results from this review suggest that currently there is insufficient data to establish the effects of berry consumption on blood pressure due to the small number of studies conducted and the heterogeneity between studies in terms of participant profiles, products, duration and baseline BP. A meta-analysis is being prepared to evaluate overall treatment effects.

References

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