Hostname: page-component-586b7cd67f-t7czq Total loading time: 0 Render date: 2024-11-28T03:59:47.276Z Has data issue: false hasContentIssue false
  • English
  • Français

DESIGN FOR SAFE REUSE OF LABWARE: INVESTIGATING METHODS FOR QUALITY ASSURANCE

Published online by Cambridge University Press:  19 June 2023

Joren Van Loon  and
Els Du Bois
Joren Van Loon*
Affiliation:
University of Antwerp
Els Du Bois
Affiliation:
University of Antwerp
*
Van Loon, Joren, University of Antwerp, Belgium, [email protected]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The problem of plastic waste in research laboratories is a significant one, with an estimated 5.5 million tonnes generated annually worldwide. Reusable labware has the potential to reduce this waste significantly, but the design of such products must take into account quality assurance to guarantee the accuracy of experiments. Insights were gathered through the generation of an overview of the available techniques for verifying labware after use and decontamination. As during different design cycles verification of prototypes is needed, these techniques were evaluated and translated to be applicable in the specific context of a design lab. Therefore, this study presents a protocol which can be used as a verification tool while designing safe, reusable labware for chemical laboratories. This protocol consists of four different steps: (i) visual inspection, (ii) mass & size comparison, (iii) leak test, and (iv) chemical stability test.

Keywords

EducationDesign managementDesign educationabstractionsemiotics
Type
Article
Information
Proceedings of the Design Society , Volume 3: ICED23 , July 2023 , pp. 1247 - 1256
Creative Commons
Creative Common License - CCCreative Common License - BYCreative Common License - NCCreative Common License - ND
This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is unaltered and is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use or in order to create a derivative work.
Copyright
The Author(s), 2023. Published by Cambridge University Press

References

Armenta, S., Garrigues, S., Esteve-Turrillas, F.A. and de la Guardia, M. (2019), “Green extraction techniques in green analytical chemistry”, TrAC Trends in Analytical Chemistry, Elsevier B.V., Vol. 116, pp. 248–253.CrossRefGoogle Scholar
ASM International. (2003), “Environmental and Chemical Effects”, Characterization and Failure Analysis of Plastics, ASM International, pp. 146–152.Google Scholar
Bishop, M.L., Fody, E.P. and Schoeff, L.E. (2018), Clinical Chemistry: Principles, Techniques, and Correlations, edited by Bishop, M.L., Fody, E.P. and Schoeff, L.E., 8th ed., Wolters Kluwer, Philadelphia.Google Scholar
Boursier, J.F., Fournet, A., Bassanino, J., Manassero, M., Bedu, A.S. and Leperlier, D. (2018), “Reproducibility, Accuracy and Effect of Autoclave Sterilization on a Thermoplastic Three-Dimensional Model Printed by a Desktop Fused Deposition Modelling Three-Dimensional Printer”, Veterinary and Comparative Orthopaedics and Traumatology, Georg Thieme Verlag, Vol. 31 No. 6, pp. 422–430.Google ScholarPubMed
Diep, T.T., Ray, P.P. and Edwards, A.D. (2022), “Methods for rapid prototyping novel labware: using CAD and desktop 3D printing in the microbiology laboratory”, Letters in Applied Microbiology, John Wiley & Sons, Ltd, Vol. 74 No. 2, pp. 247–257.CrossRefGoogle ScholarPubMed
Erokhin, K.S., Gordeev, E.G. and Ananikov, V.P. (2019), “Revealing interactions of layered polymeric materials at solid-liquid interface for building solvent compatibility charts for 3D printing applications”, Scientific Reports 2019 9:1, Nature Publishing Group, Vol. 9 No. 1, pp. 1–14.Google ScholarPubMed
Gordeev, E.G. and Ananikov, V.P. (2020), “Widely accessible 3D printing technologies in chemistry, biochemistry and pharmaceutics: applications, materials and prospects”, Russian Chemical Reviews, Vol. 89 No. 12, pp. 1507–1561.CrossRefGoogle Scholar
Gordeev, E.G., Degtyareva, E.S., Ananikov, V.P. and Zelinsky, N.D. (2016), “Analysis of 3D printing possibilities for the development of practical applications in synthetic organic chemistry”, Izvestiya Akademii Nauk. Seriya Khimicheskaya, Vol. 65 No. 6, pp. 1637–1643.Google Scholar
Gordeev, E.G., Galushko, A.S. and Ananikov, V.P. (2018), “Improvement of quality of 3D printed objects by elimination of microscopic structural defects in fused deposition modeling”, edited by McAlpine, M.C. PLOS ONE, Public Library of Science, Vol. 13 No. 6, p. e0198370.Google Scholar
Goudswaard, M., Gopsill, J., Harvey, M., Snider, C., Bell, A. and Hicks, B. (2021), “Revisiting prototyping in 2020: A snapshot of practice in UK design companies”, Proceedings of the Design Society, Volume 1: ICED21, Vol. 1, pp. 2581–2590.CrossRefGoogle Scholar
Hanif, M.A., Nadeem, F., Bhatti, I.A. and Tauqeer, H.M. (2020), Environmental Chemistry: A Comprehensive Approach, 1st ed., John Wiley & Sons, Hoboken.CrossRefGoogle Scholar
Heikkinen, I.T.S., Kauppinen, C., Liu, Z., Asikainen, S.M., Spoljaric, S., Seppälä, J. V., Savin, H., et al. (2018), “Chemical compatibility of fused filament fabrication-based 3-D printed components with solutions commonly used in semiconductor wet processing”, Additive Manufacturing, Elsevier, Vol. 23, pp. 99–107.CrossRefGoogle Scholar
International Organization for Standardization. (2008), “ISO 62:2008 Plastics — Determination of water absorption”, ISO, Geneva, available at: https://asrecomposite.com webwww.iso.orgGoogle Scholar
International Organization for Standardization. (2010), “ISO 175:2010 Plastics — Methods of test for the determination of the effects of immersion in liquid chemicals”, ISO, Geneva.Google Scholar
International Organization for Standardization. (2022a), “ISO 3146:2022 Plastics — Determination of melting behaviour (melting temperature or melting range) of semi-crystalline polymers by capillary tube and polarizing-microscope methods”, ISO, Geneva.Google Scholar
International Organization for Standardization. (2022b), “ISO 14644-10:2022 Cleanrooms and associated controlled environments - Part 10: Assessment of surface cleanliness for chemical contamination”, ISO, Geneva.Google Scholar
Isac-García, J., Dobado, J.A., Calvo-Flores, F.G. and Martínez-García, H. (2015), Experimental Organic Chemistry, 1st ed., Academic Press, Cambridge, available at:https://doi.org/10.1016/C2015-0-00644-X.Google Scholar
Kohli, R. (2012), “Methods for Monitoring and Measuring Cleanliness of Surfaces”, in Kohli, R. and Mittal, K.L.B.T.-D. in S.C. and C. (Eds.), Developments in Surface Contamination and Cleaning, Elsevier, Oxford, pp. 107–178.CrossRefGoogle Scholar
Krause, M., Gautam, K., Gazda, M. and Niraula, A. (2020), “Seize the lab waste day”, Chemistry World, available at: https://www.chemistryworld.com/opinion/reducing-plastic-waste-in-the-lab/4011550.article (accessed 28 November 2022).Google Scholar
Van Loon, J., de Jong, M., De Wael, K. and Du Bois, E. (2020), “Transposing testing from lab to on-site environment: A case of cocaine powder sampling”, Digital Proceedings of TMCE 2020, TMCE 2020 Repository, Dublin, pp. 625–636.Google Scholar
Van Loon, J., Veelaert, L., Van Goethem, S., Watts, R., Verwulgen, S., Verlinden, J.C. and Du Bois, E. (2021), “Reuse of Filtering Facepiece Respirators in the COVID-19 Era”, Sustainability, MDPI AG, Vol. 13 No. 2, p. 797.CrossRefGoogle Scholar
Medellin-Castillo, H.I. and Zaragoza-Siqueiros, J. (2019), “Design and Manufacturing Strategies for Fused Deposition Modelling in Additive Manufacturing: A Review”, Chinese Journal of Mechanical Engineering, Chinese Mechanical Engineering Society, Vol. 32 No. 1, p. 53.CrossRefGoogle Scholar
Nazir, A., Azhar, A., Nazir, U., Liu, Y.-F., Qureshi, W.S., Chen, J.-E. and Alanazi, E. (2021), “The rise of 3D Printing entangled with smart computer aided design during COVID-19 era”, Journal of Manufacturing Systems, Elsevier, Vol. 60, pp. 774–786.CrossRefGoogle ScholarPubMed
Popescu, D., Baciu, F., Amza, C.G., Cotrut, C.M. and Marinescu, R. (2021), “The Effect of Disinfectants Absorption and Medical Decontamination on the Mechanical Performance of 3D-Printed ABS Parts”, Polymers, Multidisciplinary Digital Publishing Institute, Vol. 13 No. 23, p. 4249.Google Scholar
Potting, J., Hekkert, M.P., Worrell, E. and Hanemaaijer, A. (2016), Circular Economy: Measuring Innovation in the Product Chain, Planbureau Voor de Leefomgeving, PBL publishers, The Hague.Google Scholar
Research, Prusa. (2022), “3D printers | Original Prusa 3D printers directly from Josef Prusa”, available at: https://www.prusa3d.com/category/3d-printers/ (accessed 30 November 2022).Google Scholar
Raddatz, L., de Vries, I., Austerjost, J., Lavrentieva, A., Geier, D., Becker, T., Beutel, S., et al. (2017), “Additive manufactured customizable labware for biotechnological purposes”, Engineering in Life Sciences, John Wiley & Sons, Ltd, Vol. 17 No. 8, pp. 931–939.CrossRefGoogle ScholarPubMed
Sastri, V.R. (2022), “Material Requirements for Plastics Used in Medical Devices”, Plastics in Medical Devices, 3th ed., William Andrew Publishing, Winovia LLC, pp. 65–112.CrossRefGoogle Scholar
Seidman, L.A., Moore, C.J. and Mowery, J. (2021), Basic Laboratory Methods for Biotechnology, CRC Press, Boca Raton, available at:https://doi.org/10.1201/9780429282799.CrossRefGoogle Scholar
Swallowe, G.M. (1999), Mechanical Properties and Testing of Polymers, edited by Swallowe, G.M., Vol. 3, Springer Netherlands, Dordrecht, available at:https://doi.org/10.1007/978-94-015-9231-4.CrossRefGoogle Scholar
Tranquillo, J.V., Goldberg, J. and Allen, R. (2022), Biomedical Engineering Design, 1st ed., Academic Press, Cambridge, available at:https://doi.org/10.1016/C2017-0-03558-9.Google Scholar
UCL. (2019), “Change Possible: The Strategy for a Sustainable UCL 2019 - 2024”, Univercity of London (UCL), available at: https://www.ucl.ac.uk/sustainable/sites/sustainable/files/change_possible._the_strategy_for_a_sustainable_ucl_2019-2024.pdf (accessed 21 November 2022).Google Scholar
Urbina, M.A., Watts, A.J.R. and Reardon, E.E. (2015), “Labs should cut plastic waste too”, Nature, Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved., Vol. 528 No. 7583, pp. 479–479.Google Scholar
Vinogradov, M.L., Kostrin, D.K., Karganov, M. V and Tiskovich, V.Y. (2016), “How to choose a leak detection method”, 2016 IEEE NW Russia Young Researchers in Electrical and Electronic Engineering Conference (EIConRusNW), IEEE, St. Petersburg, pp. 100–104.CrossRefGoogle Scholar
Wendt, C., Frei, R. and Widmer, A.F. (2015), “Decontamination, Disinfection, and Sterilization”, in Jorgensen, J.H., Carroll, K.C., Funke, G., Pfalle, M.A., Landry, M.L., Richter, S.S. and Warnock, D.W. (Eds.), Manual of Clinical Microbiology, 11th ed., ASM Press, Washington, DC, pp. 183–216.CrossRefGoogle Scholar
World Economic Forum, Ellen MacArthur Foundation and McKinsey & Company. (2016), The New Plastics Economy - Rethinking the Future of Plastics.Google Scholar
World Health Organization. (2020), “Decontamination and waste management”, Laboratory Biosafety Manual, Fourth Edition and Associated Monographs, 4th ed., World Health Organization, Geneva.Google Scholar
Zhou, Y. and Breyen, M.D. (2013), Joining and Assembly of Medical Materials and Devices, 1st ed., Woodhead Publishing, Cambridge.CrossRefGoogle Scholar