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A genetic-epidemiological model for Marek’s Disease in Poultry

Published online by Cambridge University Press:  22 November 2017

M Nath  and
S C Bishop
M Nath*
Affiliation:
Biomathematics and Statistics Scotland, Edinburgh, United Kingdom
S C Bishop
Affiliation:
Roslin Institute and Royal (Dick) School of Veterinary Studies, Roslin, United Kingdom
*
Email: [email protected]
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Extract

Marek’s disease (MD), caused by a herpes virus, is a very infectious, lymphoproliferative and chronic disease of poultry. Breeding for improved MD resistance poultry stock is possible since MD resistance has been associated with MHC haplotypes, QTL and candidate genes. However, integration of host genetics vis-à-vis other control strategies and the utilisation of genes or gene markers for MD in practical breeding programmes is still a challenge. The objective of the present study was to develop a basic genetic-epidemiological model for Marek’s disease infection in poultry, identify parameter spaces that describe the disease dynamics correctly and investigate the impacts of possible genetic and vaccination control strategies on overall disease dynamics.

Type
Theatre Presentations
Information
Proceedings of the British Society of Animal Science , Volume 2009 , April 2009 , pp. 197
Copyright
Copyright © The British Society of Animal Science 2009

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References

Anderson, R.M. and May, R.M. 1992. Infectious Diseases of Humans: Dynamics and Control. Oxford University Press, Oxford, UK Google Scholar
Nath, M., Woolliams, J.A. and Bishop, S.C. 2008. Journal of Animal Science. 86, 1747–1757.Google Scholar
Witter, R.L. and Schat, K.A. 2003. In: Diseases of Poultry, p. 407–465, Editor Saif, Y. M., Iowa State Press, Iowa, USA.Google Scholar