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The effect of IGF-I on the growth of secondary hair follicles of the Cashmere goat in vitro

Published online by Cambridge University Press:  05 November 2021

H. Galbraith ,
D. Sims  and
D. Hazlerigg
H. Galbraith
Affiliation:
Department of Agriculture, University of Aberdeen, 581 King Street Aberdeen AB24 5UA
D. Sims
Affiliation:
Department of Agriculture, University of Aberdeen, 581 King Street Aberdeen AB24 5UA
D. Hazlerigg
Affiliation:
Department of Agriculture, University of Aberdeen, 581 King Street Aberdeen AB24 5UA
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Extract

Factors regulating the growth of Cashmere fibre and the hair follicle cycle are poorly understood. Insulin-like growth factors (IGFs) or insulin at higher concentrations, have been shown to stimulate in vitro growth of human hair follicles (Philpott et al, 1994). The role of such mitogens in the production of cashmere fibre by the Cashmere goat has not been previously investigated. The objective the study reported here was to investigate the growth of hair follicles in the absence and presence of insulin or IGF-I using our established in vitro technique.

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Programme
Information
Proceedings of the British Society of Animal Science , Volume 1997 , 1997 , pp. 170
Copyright
Copyright © British Society of Animal Science 1997

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References

Philpott, M.P., Saunders, D. A. and Kealy, T. 1994. Effects of insulin and insulin-like growth factors on cultured human hair follicles. Journal of Investigative Dermatology 102: 857–861.CrossRefGoogle ScholarPubMed