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Analysis of association between the PrP gene and live weight and slaughter traits in an experimental flock of Swaledale sheep in the UK

Published online by Cambridge University Press:  23 November 2017

W Y N Man ,
S Brotherstone ,
B G Merrell ,
W A Murray  and
B Villanueva
W Y N Man*
Affiliation:
Scottish Agricultural College, Penicuik, Scotland, United Kingdom
S Brotherstone
Affiliation:
Scottish Agricultural College, Penicuik, Scotland, United Kingdom
B G Merrell
Affiliation:
ADAS, Newcastle, England, United Kingdom
W A Murray
Affiliation:
ADAS, Newcastle, England, United Kingdom
B Villanueva
Affiliation:
Scottish Agricultural College, Penicuik, Scotland, United Kingdom
*
Email: [email protected]
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Extract

Genetic selection based on polymorphisms identified at codons 136, 154 and 171 of the prion protein (PrP) gene is being implemented in scrapie eradication programs (e.g. Defra, 2005). These programs aim to remove the VRQ allele (associated with the highest incidence of classical scrapie) and increase the frequency of the ARR allele (which confers the highest level of resistance). However, concerns remain about how selection on the PrP gene would affect other economically important traits. The objective of this study was to investigate potential associations between the PrP alleles and lamb traits in an experimental flock of Swaledale sheep, a hill sheep breed.

Type
Theatre presentations
Information
Proceedings of the British Society of Animal Science , Volume 2006 , March 2006 , pp. 3
Copyright
Copyright © The American Society of International Law 2016

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References

Gilmour, A. R., Gogel, B. J., Cullis, B. R., Welham, S. J. and Thompson, R. 2002. ASReml User Guide Release 1.0. VSN International Ltd, Hemel Hempstead, UK.Google Scholar
Defra, .. 2005. http://www.defra.gov.uk/animalh/bse/othertses/scrapie/nsp/index.html, 2005 May 19 .Google Scholar