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The Effect of Repeated Hypoglycaemia on Plasma β-Endorphin in Gilts
Published online by Cambridge University Press: 21 November 2017
Extract
The activation of the hypothalamic-pituitary-adrenal axis is one of the best studied stress-related responses. In particular, the involvement of endogenous opioid peptides in response to pltysiological and pharmacological stimuli has been the subject of extensive study both in man and other animals (Nakao, 1979, Petraglia, 1985, Engler, 1988). However, in animal models of repeated stress, the acute response to a stressor often habituates when the stressor is presented repeatedly (Ottenweller, 1991). Hypoglycaemia is a stress which can be easily and repeatedly applied to experimental animals. The present study was performed to determine whether insulin-induced hypogrycaemia enhances the release of β-endorphin in pigs, and whether this response is maintained over repeated treatments on consecutive days.
- Type
- Pigs
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- Copyright
- Copyright © The British Society of Animal Production 1994