Hostname: page-component-745bb68f8f-kw2vx Total loading time: 0 Render date: 2025-02-07T08:48:08.832Z Has data issue: false hasContentIssue false
  • English
  • Français

Tissue Deposition of Zinc from a Zinc Chelate and from Inorganic Zinc in Rats

Published online by Cambridge University Press:  21 November 2017

Ronan Power ,
Kevin Cashman  and
Albert Flynn
Ronan Power
Affiliation:
Alltech's European Biosciences Research Centre, National University of Ireland, Galway, Eire
Kevin Cashman
Affiliation:
Department of Nutrition, National University of Ireland, Cork, Eire
Albert Flynn
Affiliation:
Department of Nutrition, National University of Ireland, Cork, Eire
Get access

Extract

Some reports have suggested differential tissue deposition of dietary trace minerals such as Zinc (Zn) when supplied to farm animals either chelated to amino acids or as inorganic salts. To test this hypothesis, an experiment was conducted to determine the ultimate tissue distribution of Zinc in rats fed either a radioactively-labeled 65Zn-chelate or 65ZnSO4. The 65Zn-chelate was prepared by heating a solution of 65ZnSO4 and an equimolar mixture of glycine and methionine for 5 minutes at 90°C. The resulting chelate was then separated from unincorporated 65ZnSO4 by gel filtration chromatography. Ten 25-d old male wistar rats (mean weight 34.5 g) were randomized by weight into two groups (n = 5/group), fasted for 18 hours and given 0.4 ml (8 μg Zn, 1 μCi65Zn) of one or other labelled solution by gavage. Four hours later, animals were returned to their normal diet for the duration of the experiment. The 65Zn activity of the animals was determined two hours after administration and daily thereafter for 7 days.

Type
Pigs
Information
Proceedings of the British Society of Animal Production (1972) , Volume 1994 , March 1994 , pp. 171
Copyright
Copyright © The British Society of Animal Production 1994

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)