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Neurogenic Pulmonary Edema in Monkeys with Global Brain Ischemia (GBI)

Published online by Cambridge University Press:  28 June 2012

Sven E. Gisvold ,
Peter Safar ,
Achiel Bleyaert  and
David Mego
Sven E. Gisvold
Affiliation:
From the Resuscitation Research Center and the Department of Anesthesiology/Critical Care Medicine, University of Pittsburgh, Pittsburgh PA 15260, USA.
Peter Safar
Affiliation:
From the Resuscitation Research Center and the Department of Anesthesiology/Critical Care Medicine, University of Pittsburgh, Pittsburgh PA 15260, USA.
Achiel Bleyaert
Affiliation:
From the Resuscitation Research Center and the Department of Anesthesiology/Critical Care Medicine, University of Pittsburgh, Pittsburgh PA 15260, USA.
David Mego
Affiliation:
From the Resuscitation Research Center and the Department of Anesthesiology/Critical Care Medicine, University of Pittsburgh, Pittsburgh PA 15260, USA.
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Extract

Ischemic and traumatic brain insults may be followed by pulmonary failure, which is a frequent cause of death in cases of multi-trauma, cardiac arrest and stroke. Pulmonary edema (PE) can occur secondary to events in the central venous nervous system (CNS). This is generally termed neurogenic pulmonary edema (NPE). It is not known which of the following 4 factors of the modified Starling equation of pulmonary edema development are involved in the development of NPE: a) filtration coefficient, that is, increased membrane permeability; b) abnormal hydrostatic pressure gradient; c) abnormal oncotic pressure gradient; and d) blockage or overwhelming of lymphatic drainage (Fig. 1).

Type
Part II: Clinical Care Topics
Information
Prehospital and Disaster Medicine , Volume 1 , supplement S1: Disaster Resuscitology , 1985 , pp. 251 - 254
Copyright
Copyright © World Association for Disaster and Emergency Medicine 1985

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