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X-ray powder diffraction data for niclosamide, C13H8N2O4Cl2

Published online by Cambridge University Press:  13 August 2015

Liu Qi Guo ,
Kai Lin Xu ,
Xiao Li Ma ,
Shan Shan Li  and
Hui Li
Liu Qi Guo
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
Kai Lin Xu
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
Xiao Li Ma
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
Shan Shan Li
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
Hui Li*
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
*
a)Author to whom correspondence should be addressed. Electronic mail: [email protected]
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Abstract

Experimental X-ray powder diffraction data, unit-cell parameters, and space group for niclosamide, C13H8N2O4Cl2, are reported [a = 13.571(1) Å, b = 7.181(8) Å, c = 13.742(3) Å, β = 97.984(7)°, unit-cell volume V = 1326.40 Å3, Z = 4, and space group P21/c]. All measured lines were indexed and are consistent with the P21/c space group. No detectable impurity was observed.

Keywords

X-ray powder diffractionniclosamide
Type
Data Reports
Information
Powder Diffraction , Volume 30 , Issue 4 , December 2015 , pp. 375 - 377
Copyright
Copyright © International Centre for Diffraction Data 2015 

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References

Harris, K. D. M. (2012). “Powder diffraction crystallography of molecular solids,” Top. Curr. Chem. 315, 133–178.Google Scholar
Helfman, D. M. (2011). “Niclosamide: an established antihelminthic drug as a potential therapy against S100A4-mediated metastatic colon tumors,” J. Natl Cancer Instrum. 103, 991–992.Google Scholar
Pan, Q. Q., Guo, P., Duan, J., Cheng, Q., and Li, H. (2012). “Comparative crystal structure determination of griseofulvin: powder X-ray diffraction versus single-crystal X-ray diffraction,” Chin. Sci. Bull. 57, 3867–3871.Google Scholar
Pawley, G. S. (1981). “Unit-cell refinement from powder diffraction scans,” J. Appl. Crystallogr. 14(6), 357–361.Google Scholar
Sanphui, P., Kumar, S. S., and Nangia, A. (2012). “Pharmaceutical cocrystals of niclosamide,” Cryst. Growth Des. 12, 4588–4599.Google Scholar
Weinbach, E. C. and Garbus, J. (1969). “Mechanism of action of reagents that uncouple oxidative phosphorylation,” Nature 221, 1016–1018.Google Scholar
Wu, C.-J., Jan, J.-T., Chen, C.-M., Hsieh, H.-P., Hwang, D.-R., Liu, H.-W., Liu, C.-Y., Huang, H.-W., Chen, S.-C., Hong, C.-H., Lin, R.-K., Chao, Y.-S., and Hsu, J. T. A. (2004). “Inhibition of severe acute respiratory syndrome coronavirus replication by niclosamide,” Antimicrob. Agents Chemother. 48, 2693–2696.Google Scholar
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