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X-ray powder diffraction analysis of abacavir hemisulfate

Published online by Cambridge University Press:  01 March 2012

Gerald Monger  and
Peter Varlashkin
Gerald Monger
Affiliation:
GlaxoSmithKline, 5 Moore Drive, Research Triangle Park, North Carolina 27707
Peter Varlashkin
Affiliation:
Metrics, Inc., 1240 Sugg Parkway, Greenville, North Carolina 27834
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Abstract

The room temperature powder pattern of abacavir hemisulfate (anti-HIV reverse transcriptase compound) was indexed using 2θ values obtained from a powder pattern spiked with an internal standard. The resulting unit cell values for the monoclinic I2 cell [nonstandard setting of C2 (No. 5)] are a=13.278(1) Å, b=8.437(1) Å, c=14.259(2) Å, β=93.87(1)°. There are two formula units [(C14H16N6O)2.H2SO4] per unit cell and Dx=1.390 g∕cm3.

Keywords

abacavir hemisulfatepowder X-ray diffractionpowder X-ray patternHIV
Type
New Diffraction Data
Information
Powder Diffraction , Volume 20 , Issue 3 , September 2005 , pp. 241 - 245
Copyright
Copyright © Cambridge University Press 2005

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References

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