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Powder Diffraction Data of Three 9-Amino-1,2,3,4- Tetrahydroacridine Alzheimer's Disease Therapeutics

Published online by Cambridge University Press:  10 January 2013

G. Bandoli ,
M. Nicolini  and
A. Ongaro
G. Bandoli
Affiliation:
Department of Pharmaceutical Sciences, Via Marzolo 5, Padua, Italy
M. Nicolini
Affiliation:
Department of Pharmaceutical Sciences, Via Marzolo 5, Padua, Italy
A. Ongaro
Affiliation:
Department of Pharmaceutical Sciences, Via Marzolo 5, Padua, Italy
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Abstract

Tacrine hydrochloride monohydrate, velnacrine maleate and suronacrine maleate have been investigated by means of X-ray powder diffraction. The unit cell dimensions, determined by single-crystal diffraction data, agree well with those of powder diffraction analysis, which is characterized by good figures of merit for the three drugs. Present work assures that single-crystals are good representatives of the commercial powdered samples, since experimental and simulated (from structure determination) powder patterns are practically identical.

Type
Research Article
Information
Powder Diffraction , Volume 6 , Issue 4 , December 1991 , pp. 196 - 199
Copyright
Copyright © Cambridge University Press 1991

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