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Exploratory Experiments

Published online by Cambridge University Press:  01 January 2022

L. R. Franklin
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Abstract

Philosophers of experiment have acknowledged that experiments are often more than mere hypothesis-tests, once thought to be an experiment's exclusive calling. Drawing on examples from contemporary biology, I make an additional amendment to our understanding of experiment by examining the way that `wide' instrumentation can, for reasons of efficiency, lead scientists away from traditional hypothesis-directed methods of experimentation and towards exploratory methods.

Type
Observation and Experiment
Information
Philosophy of Science , Volume 72 , Issue 5: Proceedings of the 2004 Biennial Meeting of The Philosophy of Science Association. Part I: Contributed Papers , December 2005 , pp. 888 - 899
Copyright
Copyright © The Philosophy of Science Association

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References

Bacon, Francis ([1620] 2000), The New Organon. Cambridge: Cambridge University Press.CrossRefGoogle Scholar
Bacon, Francis ([1627] 2002), “The New Atlantis”, in Francis Bacon, the Major Works. Oxford: Oxford University Press, Oxford World’s Classics.Google Scholar
Breeden, Linda L. (2003), “Periodic Transcription: A Cycle within a Cycle”, Periodic Transcription: A Cycle within a Cycle 13:31–38.Google ScholarPubMed
Campbell, Malcolm, and Heyer, Laurie (2003), Discovering Genomics, Proteomics, and Bioinformatics. San Francisco: CSHL Press.Google Scholar
Case, James N. (2003), Experimental Design for Combinatorial and High Throughput Materials Development. Hoboken, NJ: John Wiley and Sons.Google Scholar
Elgar, Greg (2002), “Editorial: The High Throughput Revolution”, Editorial: The High Throughput Revolution 1:4–6.Google Scholar
Galison, Peter (1987), How Experiments End. Chicago: University of Chicago Press.Google Scholar
Hacking, Ian (1983), Representing and Intervening. Cambridge: Cambridge University Press.CrossRefGoogle Scholar
Hacking, Ian (1992), “The Self-Vindication of the Laboratory Sciences”, in Pickering, Andrew (ed.), Science as Practice and Culture. Chicago: University of Chicago Press, 29–64.Google Scholar
Hereford, Lynna, Bromley, Susan, and Osley, Mary Ann (1982), “Periodic Transcription of Yeast Histone”, Periodic Transcription of Yeast Histone 30:305–310.Google ScholarPubMed
Hereford, Lynna, Osley, Mary Ann, Ludwig, J. Richard II, and McLaughlin, Calvin S. (1981), “Cell-Cycle Regulation of Yeast Histone mRNA”, Cell-Cycle Regulation of Yeast Histone mRNA 24:367–375.Google ScholarPubMed
Kosslyn, S. M. (1999), “If Neuroimaging Is the Answer, What Is the Question?”, If Neuroimaging Is the Answer, What Is the Question? 354:1283–1294.Google ScholarPubMed
Laudan, Larry (1981), Science and Hypothesis: Historical Essays on Scientific Methodology. Boston: D. Reidel Publishing Company.CrossRefGoogle Scholar
Laudan, Larry (1990), “Normative Naturalism”, Normative Naturalism 57:44–59.Google Scholar
Liang, Mingyu, Cowley, Allen W. Jr., Hessner, Martin J., Lazar, Jozef, Basile, David P., and Pietrusz, Jennifer L. (2005), “Transcriptome Analysis and Kidney Research: Toward Systems Biology”, Transcriptome Analysis and Kidney Research: Toward Systems Biology 67:2114–2122.Google ScholarPubMed
Osley, Mary Ann, Gould, Jane, Kim, Sunyoung, Kane, Michael, and Hereford, Lynna (1986), “Identification of Sequences in a Yeast Histone Promoter Involved in Periodic Transcription”, Identification of Sequences in a Yeast Histone Promoter Involved in Periodic Transcription 45:537–544.Google Scholar
Osley, Mary Ann, and Hereford, Lynna M. (1981), “Yeast Histone Genes Show Dosage Compensation”, Yeast Histone Genes Show Dosage Compensation 24:377–384.Google ScholarPubMed
Popper, Karl ([1935] 1999), The Logic of Scientific Discovery. London: Routledge.Google Scholar
Price, Clive, Nasmyth, Kim, and Schuster, Tillman (1991), “A General Approach to the Isolation of Cell Cycle-Regulated Genes in the Budding Yeast, Saccharomyces cerevisiae”, A General Approach to the Isolation of Cell Cycle-Regulated Genes in the Budding Yeast, Saccharomyces cerevisiae 218:543–556.Google ScholarPubMed
Radder, Hans (2003), “Technology and Theory in Experimental Science”, in Radder, Hans (ed.), The Philosophy of Scientific Experimentation. Pittsburgh: University of Pittsburgh Press.CrossRefGoogle Scholar
Sommer, Friedrich T., and Wichert, Andrzej (2003), Exploratory Analysis and Data Modeling in Functional Neuroimaging. Cambridge, MA: MIT Press.Google Scholar
Spellman, Paul T., Sherlock, Gavin, Zhang, Michael Q., Iyer, Vishwanath R., Anders, Kirk, Eisen, Michael B., Brown, Patrick O., Botstein, David, and Futcher, Bruce (1998), “Comprehensive Identification of Cell Cycle-Regulated Genes of the Yeast Saccharomyces cerevisiae by Microarray Hybridization”, Comprehensive Identification of Cell Cycle-Regulated Genes of the Yeast Saccharomyces cerevisiae by Microarray Hybridization 9:3273–3297.Google ScholarPubMed
Steinle, Friedrich (1997), “Entering New Fields: Exploratory Uses of Experimentation”, Entering New Fields: Exploratory Uses of Experimentation 64 (Proceedings): S65–S74.Google Scholar
Steinle, Friedrich (2002), “Experiments in History and Philosophy of Science”, Experiments in History and Philosophy of Science 10:408–432.Google Scholar