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The Wellcome Trust Lecture: Inflammatory responses to filarial connective tissue parasites

Published online by Cambridge University Press:  23 August 2011

F. Von Lichtenberg
F. Von Lichtenberg
Affiliation:
Harvard Medical School and Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA
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Summary

The inflammatory responses to lymphatic filariae and to Onchocerca volvulus are reviewed with particular attention to (1) evolutionary biology; (2) inflammatory host spectrum; (3) non-specific components; (4) immunoregulation; (5) immune evasion versus immunomodulation; (6) chronic tissue damage and scarring and (7) disease models. Basic principles of pathogenesis are emphasized, comparisons drawn with schistosome infection, and critical items of missing information are highlighted.

Type
Research Article
Information
Parasitology , Volume 94 , supplement S1: Symposia of the British Society for Parasitology Volume 24 Pathophysiological responses to parasites , January 1987 , pp. S101 - S122
Copyright
Copyright © Cambridge University Press 1987

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References

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