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Use of immunological manipulations in studying genetically controlled responses to Leishmania donovani infection in mice

Published online by Cambridge University Press:  23 August 2011

Jenefer M. Blackwell
Jenefer M. Blackwell
Affiliation:
Department of Tropical Hygiene, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT
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Extract

In the preceding paper Howard (p. 665) has given a very elegant presentation on ways in which the host immune system may be manipulated to provide valuable information about immunoregulation of parasitic infection in vivo. In our laboratory we have used some of the same manoeuvres to study immunoregulation of genetically controlled responses to Leishmania donovani infection in inbred mouse strains (Ulczak & Blackwell, 1983; Crocker, Blackwell & Bradley, 1984). As has been Howard's experience, the results obtained have not always been as one might have predicted at the outset.

Type
Research Article
Information
Parasitology , Volume 88 , Issue 4: Symposia of the British Society for Parasitology Volume 21: Parasite evasion of the immune response , August 1984 , pp. 677 - 679
Copyright
Copyright © Cambridge University Press 1984

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References

REFERENCES

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