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Transferred drug-resistance in Eimeria maxima

Published online by Cambridge University Press:  06 April 2009

L. P. Joyner
Affiliation:
Central Veterinary Laboratory, MAFF, New Haw, Weybridge, Surrey
C. C. Norton
Affiliation:
Central Veterinary Laboratory, MAFF, New Haw, Weybridge, Surrey

Extract

A series of experiments is described in which two drug-resistant strains of Eimeria maxima were passaged together in untreated chicks. The resultant oocysts were then inoculated into chicks treated with both drugs. When strains resistant to methyl benzoquate and sulphaquinoxaline or clopidol and sulphaquinoxaline were used the resultant infections were not controlled by the double treatment, indicating the acquisition of resistance factors by one strain from the other. When strains resistant to clopidol and methyl benzoquate were used the phenomenon was not observed.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1975

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References

Ball, S. J. (1966). The development of resistance to glycarbylamide and 2-chloro-4-nitro- benzamide in Eimeria tenella in chicks. Parasitology 56, 2537.CrossRefGoogle Scholar
Challey, J. R. & Jeffers, T. K. (1973). Synergism between 4-hydroxyquinoline and pyri done coccidiostats. Journal of Parasitology 59, 502–4.CrossRefGoogle Scholar
Jeffers, T. K. (1974). Genetic transfer of anticoccidial drug resistance in Eimeria tenella. Journal of Parasitology 60, 900–4.CrossRefGoogle ScholarPubMed
Joyner, L. P. & Norton, C. C. (1970). The response of recently isolated strains of Eimeria meleagrirnitis to chemotherapy. Research in Veterinary Science 11, 349–53.CrossRefGoogle ScholarPubMed
Joyner, L. P. & Norton, C. C. (1971). The recording and analysis of coccidiostatic activity: Quinolone and Pyridone compounds. Research in Veterinary Science 12, 80–8.CrossRefGoogle ScholarPubMed
Long, P. L. & Rowell, J. G. (1958). Counting oocysts of chicken coccidia. Laboratory Practice 7, 515–9.Google Scholar
McLoughlin, D. K. (1970). Coccidiosis: Experimental analysis of drug resistance. Experimental Parasitology 28, 129–36.CrossRefGoogle ScholarPubMed
Norton, C. C. & Joyner, L. P. (1975). The development of drug-resistant strains of Eimeria maxima in the laboratory. Parasitology 71, 153–65.CrossRefGoogle ScholarPubMed
Ryley, J. F. & Betts, M. J. (1973). Chemotherapy of chicken coccidiosis. In Advances in Pharmacology and Chemotherapy, Vol. 2. New York: Academic Press.Google Scholar
Walliker, D., Carter, R. & Morgan, S. (1973). Genetic recombination in Plasmodium berghei. Parasitology 66, 309–20.CrossRefGoogle ScholarPubMed
Watanabe, T. (1967). Infectious drug resistance. Scientific American 217(6), 1928.CrossRefGoogle ScholarPubMed