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Surface antigens of Toxoplasma gondii

Published online by Cambridge University Press:  06 April 2009

G. Couvreur ,
A. Sadak ,
B. Fortier  and
J. F. Dubremetz
G. Couvreur
Affiliation:
U42 INSERM, 369 rue J. Guesde, 59650 Villeneuve d'Ascq, France
A. Sadak
Affiliation:
U42 INSERM, 369 rue J. Guesde, 59650 Villeneuve d'Ascq, France
B. Fortier
Affiliation:
U42 INSERM, 369 rue J. Guesde, 59650 Villeneuve d'Ascq, France
J. F. Dubremetz*
Affiliation:
U42 INSERM, 369 rue J. Guesde, 59650 Villeneuve d'Ascq, France
*
Reprint requests to Dr J. F. Dubremetz.
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Summary

Monoclonal antibodies reacting with pellicular antigens of Toxoplasma gondii tachyzoites have been selected among hybridomas produced against this organism by immunofluorescence assay. These antigens have been further characterized by immunofluorescence on living zoites, Western immunoblotting and immunoprecipitation of lactoperoxidase surface radio-iodinated tachyzoite lysates. The simultaneous characterization of 5 different surface antigens (P43, P35, P30, P23, P22) some of which have already been studied individually allowed a better definition of these antigens and the characterization of a yet undescribed surface molecule (P23).

Type
Research Article
Information
Parasitology , Volume 97 , Issue 1 , August 1988 , pp. 1 - 10
Copyright
Copyright © Cambridge University Press 1988

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References

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