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Schistosoma mansoni: the occurrence of microvilli on the surface of the tegument during transformation from cercaria to schistosomulum

Published online by Cambridge University Press:  06 April 2009

Diane J. McLaren  and
D. J. Hockley
Diane J. McLaren
Affiliation:
National Institute for Medical Research, Mill Hill, London NW7 1AA and Institute of Ophthalmology, Judd Street, London WClH 9QS
D. J. Hockley
Affiliation:
National Institute for Medical Research, Mill Hill, London NW7 1AA and Institute of Ophthalmology, Judd Street, London WClH 9QS
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Extract

Microvilli are developed on the surface of Schistosoma mansoni schistosomula during penetration of the host skin; they form rapidly but are lost approximately 90 min after penetration. Identical microvilli are also formed on schistosomula which have penetrated a mouse skin preparation in vitro, and on schistosomula prepared by mechanical separation of the tail from the body of the cercaria. The microvilli, which are limited by the trilaminate tegumental membrane of the cercaria, eventually degenerate and are cast off from the surface of the tegument. There is little change in the surface area of the schistosomulum at this time, and the formation and loss of microvilli coincides with the replacement of the cercarial tegumental membrane by the new heptalaminate membrane. It is suggested that during the cercaria/schistosomulum transformation, some intramembraneous components of the original cercarial membrane may migrate into the new heptalaminate membrane and thus be retained, while other peripheral components such as the glycocalyx are almost certainly lost.

Type
Research Article
Information
Parasitology , Volume 73 , Issue 2 , October 1976 , pp. 169 - 187
Copyright
Copyright © Cambridge University Press 1976

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