Hostname: page-component-78c5997874-fbnjt Total loading time: 0 Render date: 2024-11-04T19:32:11.298Z Has data issue: false hasContentIssue false
  • English
  • Français

Recent advances in schistosome biochemistry

Published online by Cambridge University Press:  06 April 2009

G. C. Coles
G. C. Coles
Affiliation:
Department of Zoology, Morrill Science Center, University of Massachusetts, Amherst, MA 01003–0027
Get access Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Trends and Perspectives
Information
Parasitology , Volume 89 , Issue 3 , December 1984 , pp. 603 - 637
Copyright
Copyright © Cambridge University Press 1984

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Alving, C. R., Joseph, K. C., Lindsley, H. B. & Schoenbechler, M. J. (1974). Immune damage to liposomes containing lipids from Schistosoma mansoni worms. Proceedings of the Society for Experimental Biology and Medicine 146, 458–61.CrossRefGoogle ScholarPubMed
AoKi, T. & Oya, H. (1979). Glutamine-dependent carbamoyl-phosphate synthetase and control of pyrimidine biosynthesis in the parasitic helminth Schistosoma mansoni. Comparative Biochemistry and Physiology 63B, 511–15.Google Scholar
Araujo, N., Katz, N., Dias, E. P. De. (1980). Susceptibility to chemotherapeutic agents of strains of Schistosoma mansoni isolated from treated and untreated patients. American Journal of Tropical Medicine and Hygiene 29, 890–4.CrossRefGoogle ScholarPubMed
Asch, H. L. (1975). Effect of selected chemical agents on longevity and infectivity of Schistosoma mansoni cercariae. Experimental Parasitology 38, 208–16.Google Scholar
Asch, H. L. & Dresden, M. H. (1977). Schistosoma mansoni: inhibition of cercarial ‘penetration’ proteases by components of mammalian blood. Comparative Biochemistry and Physiology 58B, 89–95.Google ScholarPubMed
Asch, H. L. & Dresden, M. H. (1979). Acidic thiol proteinase activity of Schistosoma mansoni egg extracts. Journal of Parasitology 65, 543–9.CrossRefGoogle ScholarPubMed
Asch, H. L. & Read, C. P. (1975 a). Transtegumental absorption of amino acids by male Schistosoma mansoni. Journal of Parasitology 61, 378–9.CrossRefGoogle ScholarPubMed
Asch, H. L. & Read, C. P. (1975 b). Membrane transport in Schistosoma mansoni: transport of amino acids by adult males. Experimental Parasitology 38, 123–35.CrossRefGoogle ScholarPubMed
Atkinson, K. H. & Atkinson, B. G. (1980). Biochemical basis for the continuous copulation of female Schistosom masoni. Nature, London 283, 478–9.Google Scholar
Atkinson, K. H. & Atkinson, B. G. (1981). Protein Synthesis in vivo by Schistosoma mansoni cercariae. Molecular and Biochemical Parasitology 4, 205–16.CrossRefGoogle ScholarPubMed
Atkinson, B. G. & Atkinson, K. H. (1982). Schistosoma mansoni: one- and two-dimensional electrophoresis of proteins synthesized in vitro by males, females, and juveniles. Experimental Parasitology 53, 26–38.Google Scholar
Auriault, C., Capron, M. & Capron, A. (1982). Activation of rat and human eosinophils by soluble factor(s) released by Schistosoma mansoni schistosoinula. Cellular Immunology 66, 59–69.CrossRefGoogle Scholar
Auriault, C., Joseph, M., Dessaint, J. P. & Capron, A. (1980). Inactivation of rat macrophages by peptides resulting from cleavage of IgG by schistosomula larvae proteases. Immunological Letters 2, 135–9.CrossRefGoogle Scholar
Auriault, C., Ouaissi, M. A., Torpier, G., Eisen, H. & Capron, A. (1981). Proteolytic cleavage of IgG bound to the Fc receptor of Schistosoma mansoni schistosomula. Parasite Immunology 3, 33–44.CrossRefGoogle Scholar
Auriault, C., Pierce, R., Cesari, I. M. & Capron, A. (1982). Neutral protease activities at different developmental stages of Schistosoma mansoni in mammalian hosts. Comparative Biochemistry and Physiology 72B, 377–84.Google ScholarPubMed
Austin, F., Frappaolo, P., Gilbert, B., Landis, W., Rosa, M. N. Da & Stirewalt, M. (1974). Further studies of Schistosoma mansoni cercarial stimulation by crude egg lecithin and other lipids. Parasitology 69, 455–63.Google Scholar
Baba, E. H., Homewood, C. A., Gazzinelli, G. & Atkinson, E. M. (1977). Comparison of proteolytic enzymes from cercarial extract and secretion. Comparative Biochemistry and Physiology 57B, 55–7.Google Scholar
Becker, W. (1977). Zur Stoffwechselphysiologie der Miracidien von Schistosoma mansoni wahrend ihrer Aktivierung innerbalb der Eischale. Zeitschrift für Parasitenkunde 52, 69–79.Google Scholar
Becker, B., Mehlhorn, H., Andrews, P., Thomas, H. & Eckert, J. (1980). Light and electron microscopic studies on the effect of praziqunatel on Schistosoma mansoni, Dicrocoelium dendriticum and Fasciola hepatica (Trematoda) in vitro. Zeitschrift für Parasitenkunde 63, 113–28.Google Scholar
Bedi, A. J. K. & Isseroff, H. (1979). Bile duct hyperplasia in mice infected with Schistosoma mansoni. International Journal for Parasitology 9, 401–4.CrossRefGoogle ScholarPubMed
Bennett, J. L. (1980). Characteristics of antischistosomal benzodiazepine binding sites in Schistosoma mansoni. Journal of Parasitology 66, 742–7.Google Scholar
Bennett, J. L. (1982). Methods used to study the nervous system of small parasitic helminths. In Cues that Influence Behaviour of Internal Parasites (ed. Barley, W. S.), pp. 22–31. Alabama: U.S. Department of Agriculture.Google Scholar
Bennett, J. L. & Bueding, E. (1973). Uptake of 5-hydroxytryptamine by Schistosoma mansoni. Molecular Pharmacology 9, 311–19.Google ScholarPubMed
Bennett, J. L. & Gianutsos, G. (1978). Disulfiram - a compound that selectively induces abnormal egg production and lowers norepinephrine levels in Schistosoma mansoni. Biochemical Pharmacology 27, 817–20.Google Scholar
Bennett, J. L. & Seed, J. L. (1977). Characterization and isolation of concanavalin A binding sites from the epidermis of S. mansoni. Journal of Parasitology 63, 250–8.CrossRefGoogle ScholarPubMed
Bennett, J. L., Seed, J. L. & Boff, M. (1978). Fluorescent histochemical localization of phenol oxidase in female Schistosoma mansoni. Journal of Parasitology 64, 941–4.Google Scholar
Bloom, A. (1981). Studies of the mode of action of metrifonate and DDVP in schistosomes - cholinesterase activity and the hepatic shift. Acta Pharmacologica et Toxicologica 49, Suppl. 5, 109–13.Google Scholar
Boctor, F. N., Nash, T. E. & Cheever, A. W. (1979). Isolation of a polysaccharide antigen from Schistosoma mansoni eggs. Journal of Immunology 122, 39–43.CrossRefGoogle ScholarPubMed
Bogitsch, B. J. (1975 a). Cytochemistry of gastrodermal autophagy following starvation in Schistosoma mansoni. Journal of Parasitotogy 61, 237–48.CrossRefGoogle Scholar
Bogitsch, B. J. (1975 b). Cytochemical localization of peroxidase activity in the miracidium of Schistosoma mansoni. Journal of Parasitology 61, 621–6.Google Scholar
Bogitsch, B. J. & Carter, O. S. (1980). Schistosoma mansoni: radioautography of colchicine's effect on [3H] proline incorporation into adults in vitro. Experimental Parasitology 49, 319–27.Google Scholar
Bogitsch, B. J. & Dresden, M. H. (1983). Fluorescent histochemistry of acid proteases in adult Schistosoma mansoni and Schistosoma japonicum. Journal of Parasitology 69, 106–10.Google Scholar
Bout, D., Dupas, H., Capron, M., Tran, Van Ky P. & Capron, A. (1976). Drugs as ligands of immunogenic molecules in parasites: an approach to the isolation of target-antigens. In Biochemistry of Parasites and Host-Parasite Relationships (ed. Van den Bossche, H.), pp. 325–333. Amsterdam: Elsevier/North-Holland Biomedical Press.Google Scholar
Bout, P., Dupas, H., Capron, M., El Gazawi, A., Carlier, Y., Delacourte, A. & Capron, A. (1978). Purification, immunochemical and biological characterization of malate dehydrogenase of Schistosoma mansoni. Immunochemistry 15, 633–8.CrossRefGoogle ScholarPubMed
Brazier, J. B. & Jaffe, J. J. (1973). Two types of pyruvate kinase in schistosomes and filariae. Comparative Biochemistry and Physiology 44B, 145–55.Google Scholar
Bricker, C. S., Depenbush, J. W., Bennett, J. L. & Thompson, D. P. (1983). The relationship between tegumental disruption and muscle contraction in Schistosoma mansoni exposed to various compounds. Zeitschrift für Parasitenkunde 69, 61–71.Google Scholar
Briggs, M. H. (1972). Metabolism of steroid hormones by schistosomes. Biochimica et biophysica acta 280, 481–5.CrossRefGoogle ScholarPubMed
Brink, L. H., Krueger, K. L. & Harris, C. (1980). Stage-specific antigens of Schistosoma mansoni. In The Host Invader interplay (ed. Van den Bossche, H.), pp. 393–404. Amsterdam: Elsevier/North-Holland Biomedical Press.Google Scholar
Brown, A. P., Remold, H. G., Warren, K. S. & David, S. R. (1977). Partial purification of antigens from eggs of Schistosoma mansoni that elicit delayed hypersensitivity. Journal of Immunology 119, 1275–9.Google Scholar
Brown, J. N. & Smith, T. M. (1977). Phosphodiesterase activity in adult Schistosoma japonicum. Transactions of the Royal Society of Tropical Medicine and Hygiene 71, 356–7.CrossRefGoogle ScholarPubMed
Bruce, J. I., Ruff, M. D., Belusko, R. J. & Werner, J. K. (1972). Schistosoma mansoni and Schistosoma japonicum: utilization of amino acids. International Journal for Parasitology 2, 425–30.Google Scholar
Bueding, E. (1950). Carbohydrate metabolism of Schistosoma mansoni. Journal of General Physiology 33, 475–95.Google Scholar
Bueding, E. & Fisher, J. (1982). Metabolic requirements of schistosomes. Journal of Parasitology 68, 208–12.Google Scholar
Bueding, E., Fisher, J. & Bruce, J. (1973). The antischistosomal activity of a chloroindazole analog of hycanthone in mice infected with Shistosoma mansoni. Journal of Pharmacology and Experimental Therapeutics 186, 402–7.Google Scholar
Bueding, E., Liu, C. L. & Rogers, S. H. (1972). Inhibition by metrifonate and dichiorvos of cholinesterase in schistosomes. British Journal of Pharmacology 46, 480–7.Google Scholar
Byram, J. E. & Senft, A. W. (1979). Structure of the schistosome eggshell: amino acid analysis and incorporation of labelled amino acids. American Journal of Tropical Medicine and Hygiene 28, 539–47.Google Scholar
Campbell, D. L., Frappaolo, P. J. F., Stirewalt, M. A. & Dresden, M. H. (1976). Schistosoma mansoni: partial characterization of enzyme(s) secreted from the preacetabular glands of cercariae. Experimental Parasitology 40, 33–40.CrossRefGoogle ScholarPubMed
Camus, D., Nosseir, A., Mazingue, C. & Capron, A. (1981). Immunoregulation by Schistosoma mansoni. Immunopharmacology 3, 193–204.Google Scholar
Capron, A., Auriault, C., Mazinque, C., Capron, M. & Torpier, G. (1980). Schistosome mechanisms of evasion. In The Host Invader Interplay (ed. Van den Bossche, H.), pp. 217–225. Amsterdam: Elsevier/North-Holland Biomedical Press.Google Scholar
Capron, A., Dessaint, J. P., Capron, M., Joseph, M. & Torpier, G. (1978). Effector mechanisms of immunity to schistosomes and their regulation. Immunological Reviews 61, 41–66.Google Scholar
Carlier, Y., Bout, D., Strecker, G., Debray, H. & Capron, A. (1980). Purification, immunochemical, and biologic characterization of the Schistosoma circulating M antigen. Journal of Immunology 124, 2442–50.Google Scholar
Carter, C. E. & Colley, D. C. (1978). An electrophoretic analysis of Schistosoma mansoni soluble egg antigen preparation. Journal of Parasitology 64, 385–90.CrossRefGoogle ScholarPubMed
Carter, C. E. & Colley, D. G. (1979). Partial purification and characterization of Schistosoma mansoni soluble egg antigen using Con A-Sepharose chromatography. Journal of Immunology 122, 2204–9.Google Scholar
Carter, C. E. & Colley, D. G. (1981). Schistosoma japonicum soluble egg antigens: separation by Con-A chromatography and immunoaffinity purification. Molecular Immunology 18, 219–25.Google Scholar
Catto, B. A. (1981). Schistosoma mansoni: decarboxylation of 5-hydroxytryptophan, L-dopa, and L-histidine in adults and larval schistosomes. Experimental Parasitology 51, 152–7.Google Scholar
Catto, B. A. & Ottesen, E. A. (1979). Serotonin uptake in schistosomules of Schistosoma mansoni. Comparative Biochemistry and Physiology 63C, 235–42.Google Scholar
Cesari, I. M. (1974). Schistosoma mansoni: distribution and characteristics of alkaline and acid phosphatase. Experimental Parasitology 36, 405–14.Google Scholar
Cesari, I. M. (1976). Occurrence of an agglutinin in Schistosoina mansoni. International Journal for Parasitology 6, 295–8.Google Scholar
Cesari, I. M. & Marchiani, C. (1977). Inhibition studies on the Schistosoma mansoni agglutinin. International Journal for Parasitology 7, 275–9.Google Scholar
Cesari, I. M. & Marchiani, C. A. (1978). Schistosoma mansoni: phospholipid nature of the ‘agglutinin’. Experimental Parasitology 45, 175–82.Google Scholar
Cesari, I. M., Simpson, A. J. G. & Evans, W. H. (1981). Properties of a series of tegumental membrane-bound phosphohydrolase activities of Schistosoma mansoni. The Biochemical Journal 198, 467–73.Google Scholar
Cesari, I. M., Torpier, G. & Capron, A. (1983). Schistosoma mansoni: surface membrane isolation by polycationic beads. Experimental Parasitology 56, 119–28.Google Scholar
Chappell, L. H. (1974). Methionine uptake by larval and adult Schistosoma mansoni. International Journal for Parasitology 4, 361–9.Google Scholar
Chappell, L. H. & Walker, E. (1982). Schistosoma mansoni: incorporation and metabolism of protein amino-acids in vitro. Comparative Biochemistry and Physiology 73B, 701–7.Google ScholarPubMed
Chou, T-C. T., Bennett, J. & Bueding, E. (1972). Occurrence and concentrations of biogenic amines in trematodes. Journal of Parasitology 58, 1098–102.CrossRefGoogle ScholarPubMed
Chou, T-C. T., Bennett, J. L., Pert, C. & Bueding, E. (1973). Effect of hycanthone and of two of its structural analogs on levels and uptake of 5-hydroxytryptamine in Schistosoma mansoni. Journal of Pharmacology and Experimental Therapeutics 186, 408–15.Google Scholar
Cioli, D. & Knopf, P. M. (1980). A study of the mode of action of hycanthone against Schistosoma mansoni in vivo and in vitro. American Journal of Tropical Medicine and Hygiene 19, 220–6.CrossRefGoogle Scholar
Cohen, C., Reineardt, B., Castellani, L., Norton, P. & Stirewalt, M. (1982). Schistosome surface spines are crystals of actin. Journal of Cell Biology 95, 987–8.CrossRefGoogle ScholarPubMed
Coles, G. C. (1972). Oxidative phosphorylation in adult Schistosoma mansoni. Nature, London 240, 488–9.Google Scholar
Coles, G. C. (1973). The metabolism of schistosomes: a review. International Journal of Biochemistry 4, 319–37.Google Scholar
Coles, G. C. (1975). Fluke biochemistry - Fasciola and Schistosoma. Helminthological Abstracts 44 A, 147–62.Google Scholar
Coles, G. C. (1979). The effect of praziquantel on Schistosoma mansoni. Journal of Helminthology 53, 31–3.CrossRefGoogle ScholarPubMed
Coles, G. C. & Chappell, L. H. (1979). Schistosoma mansoni: effect of antimony on immature and adult worms. Experimental Parasitology 47, 59–63.Google Scholar
Cordiero, M. N. & Gazzinelli, G. (1979). Schistosoma mansoni: resolution and molecular weight estimates of tegument glycoproteins by polyacrylamide gel electrophoresis. Experimental Parasitology 48, 337–44.Google Scholar
Cornford, E. M. (1982). Correlation between lipid partition coefficients and surface permeation in Schistosoma japonicum. Journal of Membrane Biology 64, 217–24.CrossRefGoogle ScholarPubMed
Cornford, E. M. & Huot, M. E. (1981). Glucose transfer from male to female schistosomes. Science 213, 1269–71.Google Scholar
Cornford, E. M. & Oldendorf, W. H. (1979). Transintegumental uptake of metabolic substrates in male and female Schistosoma mansoni. Journal of Parasitology 65, 357–63.CrossRefGoogle ScholarPubMed
Crabtree, G. W. & Senft, A. W. (1974). Pathways of nucleotide metabolism in Schistosoma mansoni - V. Adenosine cleavage enzyme and effects of purine analogues on adenosine metabolism in vitro. Biochemical Pharmacology 23, 649–60.Google Scholar
Cruise, K. M., Mitchell, G. F., Garcia, E. G., Tiu, W. U., Hocking, R. E. & Anders, R. F. (1983). Sj23, the target antigen in Schistosoma japonicum adult worms of an immunodiagnostic hybridoma antibody. Parasite Immunology 5, 37–46.Google Scholar
Dammonville, M., Auriault, C., Pierce, R. J. & Capron, A. (1982). Antigenic properties of Schistosoma mansoni aminopeptidases: evolution during the development in mammalian hosts. Molecular and Biochemical Parasitology 6, 265–75.Google Scholar
Deelder, A. M., Kornelis, D., Marck, E. A. Van E., Eveleigh, P. C. & Egmond, J. G. Van (1980). Schistosoma mansoni: characterization of two circulating polysaccharide antigens and the immunological response to these antigens in mouse, hamster, and human infections. Experimental Parasitology 50, 16–32.Google Scholar
Deelder, A. M., Reinders, P. N. & Rotmans, J. P. (1977). Purification studies on an acidic protease from adult Schistosoma mansoni. Acta Leidensia 45, 91–103.Google Scholar
Dei-Cas, E., Dhainaut-Courtois, N. & Biguet, J. (1981). Contribution à l'étude du système nerveux des formes adultes et larvaires de Schistosoma mansoni Sambon, 1907 (Trematoda Digenea). II. Rôle de Ia sérotonine et de Ia dopamine. Annales de Parasitologies 56, 271–84.Google Scholar
Dei-Cas, E., Dhainaut-Courtois, N., Dhainaut, A. & Vernes, A. (1979). Ultrastructural localization of tritiated 5-HT in adult Schistosoma mansoni. A preliminary report. Biologie Cellulaire 35, 321–4.Google Scholar
Oliveira, C. C. De, Figueiredo, E. A., Gazzinelli, C., Howells, R. E. & Pellegrino, J. (1975). Biochemical changes in the transformation of Schistosoma mansoni cercariae to schistosomules. Comparative Biochemistry and Physiology 51B, 417–20.Google Scholar
Depenbusch, J. W., Bricker, C. S., Bennett, J. L. & Pax, R. A. (1982). Effect of Triton X-100 on tegument and muscle in Schistosoma mansoni. Journal of Parasitology 68, 884–91.Google Scholar
Dessaint, J. P., Camus, D., Fischer, E. & Capron, A. (1977). Inhibition of lymphocyte proliferation by factor(s) produced by Schistosoma mansoni. European Journal of Immunology 7, 624–9.Google Scholar
Dessein, A., Samuelson, J. C., Butterworth, A. E., Hogan, M., Sherry, B. A., Vadas, M. A. & David, J. R. (1981). Immune evasion of Schistosoma mansoni: loss of susceptibility to antibody or complement-dependent eosinophil attack by schistosomula cultured in medium free of macromolecules. Parasitology 83, 357–74.Google Scholar
Dissous, C., Dissous, C. & Capron, A. (1981). Isolation and characterization of surface antigens from Schistosoma mansoni schistosomula. Molecular and Biochemical Parasitology 3, 215–25.Google Scholar
Doenhoff, M. J. & Bain, J. (1978). The immune-dependence of schistosomicidal chemotherapy: relative lack of efficacy of an antimonial in Schistosoma mansoni-infected mice deprived of their T-cells and the demonstration of drug-antiserum synergy. Clinical and Experimental Immunology 33, 232–8.Google ScholarPubMed
Dotson, M. J., Chu, S. H. & Hillman, G. R. (1981). Selective inhibition of schistosorne acetylcholinesterase by dansylated acetylcholine analogs. Comparative Biochemistry and Physiology 68C, 229–30.Google Scholar
Dresden, M. H. & Asoh, H. L. (1977). Calcium carbonate content of the preacetabular glands of Schistosonia mansoni cercariae. Journal of Parasitology 63, 163–5.Google Scholar
Dresden, M. H. & Deelder, A. M. (1979). Schistosoma mansoni: thiol proteinase properties of adult worm hemoglobinase. Experimental Parasitology 48, 190–7.Google Scholar
Dresden, M. H. & Edlin, E. M. (1974). Schistosoma mansoni: effect of some cations on the proteolytic enzymes of eercariae. Experimental Parasitology 35, 299–303.Google Scholar
Dresden, N. H. & Edltn, E. M. (1975). Schistosoma mansomi: calcium content of cercariae and its effects on protease activity in vitro. Journal of Parasitology 61, 398–402.Google Scholar
Dresden, M. H., Lewis, J. C. & Kaisxo, I. (1977). Proteolytic action of Schistosoma mansoni cercarial proteases on keratin and basement membrane proteins. Journal of Parasitology 63, 941–3.Google Scholar
Dresden, M. H., Rutledge, M. L. & Chappell, C. L. (1981). Properties of the acid thiol proteinase from Schistosoma mansoni adults. Molecular and Biochemical Parasitology 4, 61–6.Google Scholar
Dresden, M. H., Sung, C. K. & Deelder, A. M. (1983). A monoclonal antibody from infected mice to a Schistosoma mansoni egg proteinase. Journal of Immunology 130, 1–3.Google Scholar
Drummond, G. S. & Kappas, A. (1981). Potent heme-degrading action of antimony and antimony-containing parasiticidal agents. Journal of Experiment Medicine 153, 245–56.Google Scholar
Erasmus, D. A. (1974). The application of X-ray analysis in the transmission electron microscope to a study of drug distribution in the parasite Schistosonia mansoni (Platyhelm inths). Journal of Microscopy 102, 59–69.Google Scholar
Erasmus, D. A. (1975 a). The subcellular localization of labelled tyrosine in the vitelline cells of Schistosoma mansoni. Zeitschrift für Parasitenkunde 46, 75–81.Google Scholar
Erasmus, D. A. (1975 b). Schistosoma mansoni: development of the vitelline cell, its role in drug sequestration, and changes induced by astiban. Experimental Parasitology 38, 240–56.Google Scholar
Erasmus, D. A. & Davies, T. W. (1979). Schistosoma mansoni and S. haematobium: calcium metabolism of the vitelline cell. Experimental Parasitology 47, 91–106.Google Scholar
Erasmus, D. A. & Popiel, I. (1980). Schistosoma mansoni: drug-induced changes in the cell population of the vitelline gland. Experimental Parasitology 50, 171–87.CrossRefGoogle ScholarPubMed
Ercoli, N. & Payares, G. (1974). Schistosoma mansoni: early antimonial treatment of infected mice. Experimental Parasitology 35, 171–8.CrossRefGoogle ScholarPubMed
Ernst, S. C. (1975). Biochemical and cytochemical studies of digestive—absorptive functions of oesophagus, caecum, and tegument in Schistosoma mansoni: acid phosphatase and tracer studies. Journal of Parasitology 61, 633–47.Google Scholar
Feldmeier, H., Doehring, E., Daffala, A. A., Omer, A. H. & Dietrich, M. (1982). Efficacy of metrifonate in urinary schistosomiasis: comparison of reduction of Schistosoma haeniatobium and S. mansoni eggs. American Journal of Tropical Medicine and Hygiene 31, 1188–94.Google Scholar
Fetterer, R. H., Pax, R. A. & Bennett, J. L. (1977). Schistosoma mansoni: direct method for simultaneous recording of electrical and motor activity. Experimental Parasitology 43, 286–94.Google Scholar
Fetterer, R. H., Pax, R. A. & Bennett, J. L. (1980 a). Schistosoma manuoni: characterization of the electrical potential from the tegument of adult males. Experimental Parasitology 49, 353–65.Google Scholar
Fetterer, R. H., Pax, R. A. & Bennett, J. L. (1980 b). Praziquantel, potassium and 2,4- dinitrophenol: analysis of their action on the musculature of Schistosonia mansoni. European Journal of Pharmacology 64, 31–8.CrossRefGoogle Scholar
Fetterer, R. H., Pax, R. A., Strand, S. & Bennett, J. L. (1978). Schistosoma mansoni: physical and chemical factors affecting the mechanical properties of the adult male muscu lature. Experimental Parasitology 46, 59–71.Google Scholar
Fetterer, R. H., Pax, R. A., Thompson, D., Bricker, C. & Bennett, J. L. (1980 a). Electrophysiological and biochemical properties of the tegument of Schistosoma mansoni. In The Host Invader Interplay (ed. Van den Bossche, H.), pp. 105–116. Amsterdam: Elsevier/North-Holland Biomedical Press.Google Scholar
Fetterer, R. H., Pax, R. A., Thompson, D., Bricker, C. & Bennett, J. L. (1980 b). Praziquantel: mode of its antischistosomal action. In The Host Invader Interplay (ed. Van den Bossche, H.), pp. 695–698. Amsterdam: Elsevier/North-Holland Biomedical Press.Google Scholar
Fetterer, R. H., Waa, J. A. Van De & Bennett, J. A. (1980). Characterization and localization of ouabain receptors in Schistosoma mansoni. Molecular and Biochemical Parasitology 1, 209–19.Google Scholar
Fetterer, R. H., Wolde Mussie, E. & Bennett, J. L. (1981). Adenosine triphosphate-dependent ouabain binding in homogenates of male and female Schistosoma mansoni. Comparative Biochemistry and Physiology 69B, 803–8.Google Scholar
Fletcher, M., Loverde, P. T. & Kuntz, R. E. (1981). Electrophoretic differences between Schistosoma mansoni and S. rodhaini. Journal of Parasitology 67, 593–5.Google Scholar
Foster, R. & Cheetham, B. L. (1973). Studies with the schistosomicide oxamniquine (UK-4217). 1. Activity in rodents and in vitro. Transactions of the Royal Society of Tropical Medicine and Hygiene 67, 674–84.Google Scholar
Fried, B., Imperia, P. S. & Eveland, L. K. (1981). Neutral lipids in adult male and female Schistosoma mansoni and release of neutral lipids by adults maintained in vitro. Comparative Biochemistry and Physiology 68B, 111–12.Google Scholar
Fripp, P. J., Williams, G. & Crawford, M. A. (1976). The differences between the long chain polyenoic acids of adult Schistosoma mansoni and the serum of its host. Comparative Biochemistry and Physiology 53B, 505–97.Google Scholar
Gazzinelli, G., Oliveira, C. C. de, Figueiredo, E. A., Pereira, L. H., Coelho, P. M. Z. & Pellegrino, J. (1973). Schistosoma mansoni: biochemical evidence for morphogenetic change from cercaria to schistosomule. Experimental Parasitology 34, 181–8.Google Scholar
Gear, N. R. (1976). The effect of inhibitors on the hydrolysis of acetylcholine by four species of Schistosoma. Comparative Biochemistry and Physiology 55C, 5–10.Google Scholar
Gear, N. R. & Fripp, P. J. (1974). Comparison of the characteristics of acetyicholinesterase present in four species of Schistosoma. Comparative Biochemistry and Physiology 47B, 743–52.Google Scholar
Gitter, B. D. & Damian, R. T. (1982). Murine alloantigen acquisition by schistosomula of Schistosoma mansoni: further evidence for the presence of K and I region gene products on the tegumental surface. Parasite Immunology 4, 383–93.Google Scholar
Gitter, B. D., McCormick, S. L. & Damian, R. T. (1982). Murine alloantigen acquisition by Schistosoma mansoni: presence of H-2K determinants on adult worms and failure of allogeneic lymphocytes to recognize acquired MHC gene products on schistosomula. Journal of Parasitology 68, 513–18.Google Scholar
Goldberg, M., Flescher, E., Gold, D. & Lengy, J. (1980). Ornithine-δ-transaminase from the liver fluke Fasciola hepatica and the blood fluke Schistosoma mansoni: a comparative study. Comparative Biochemistry and Physiology 65B, 605–13.Google Scholar
Goldberg, M., Flescher, E. & Lengy, J. (1979). Schistosoma mansoni: partial purification and properties of ornithine-δ-transaminase. Experimental Parasitology 47, 333–41.CrossRefGoogle ScholarPubMed
Goldberg, M., Gold, D., Flescher, E. & Lengy, J. (1980). Effect of oxamniquine on Schistosoma mansoni: some biological and biochemical observations. Biochemical Pharmacology 29, 838–40.Google Scholar
Goldring, O. L., Clegg, J. A., Smithers, S. R. & Terry, R. J. (1976). Acquisition of human blood group antigens by Schistosoma mansoni. Clinical and Experimental Immunology 26, 181–7.Google Scholar
Goldring, O. L., Kusel, J. R. & Smithers, S. R. (1977). Schistosoma mansoni: origin in vitro of host-like surface antigens. Experimental Parasitology 43, 82–93.CrossRefGoogle ScholarPubMed
Goldring, O. L., Sher, A., Smithers, S. R. & McClaren, D. J. (1977). Host antigens and parasite antigens of murine Schistosoma mansoni. Transactions of the Royal Society of Tropical Medicine and Hygiene 71, 144–8.Google Scholar
Grausz, D., Dissous, C., Capron, A. & Roskam, W. (1983). Messenger RNA extracted from Schistosoma mansoni larval forms codes for parasite antigens when translated in vitro. Molecular and Biochemical Parasitology 7, 293–301.Google Scholar
Haas, W. & Schmitt, R. (1982). Characterization of chemical stimuli for the penetration of Schistosoma mansoni cercariae. 1. Effective substances, host specificity. Zeitschrift für Parasitenkunde 66, 293–307.Google Scholar
Hamburger, J., Lustigman, S., Arap Siongok, T. K., Ouma, J. H. & Mahmoud, A. A. F. (1982). Characterization of a purified glycoprotein from Schistosoma mansoni eggs: specificity, stability, and the involvement of carbohydrate and peptide moieties in its serological activity. Journal of Immunology 128, 1864–9.Google Scholar
Hamburger, J., Pelley, R. P. & Warren, K. S. (1976). Schistosoma mansoni soluble egg antigens: determination of the stage and species specificity of their serological reactivity by radioimmunoassay. Journal of Immunology 117, 1561–6.Google Scholar
Harrison, D. J., Carter, C. E. & Colley, D. G. (1979). Immunoaffinity purification of Schistosoma mansoni soluble egg antigens. Journal of Immunology 122, 2210–17.Google Scholar
Hayunga, E. G., Murrell, K. D., Taylor, D. W. & Vannier, W. E. (1979 a). Isolation and characterization of surface antigens from Schistosoma mansoni. I. Evaluation of techniques for radioisotope labelling of surface proteins from adult worms. Journal of Parasitology 65, 488–96.Google Scholar
Hayunga, E. G., Murrell, K. D., Taylor, D. W. & Vannier, W. E. (1979 b). Isolation and characterization of surface antigens from Schistosoma mansoni. II. Antigenicity of radiolabelled proteins from adult worms. Journal of Parasitology 65, 497–506.Google Scholar
Hayunga, E. G., Sumner, M. P. & Steck, M. Jr. (1982). Isolation of a concanavalin A-binding glycoprotein from adult Schistosoma japonicum. Journal of Parasitology 68, 960–1.Google Scholar
Hayunga, E. G., Vannier, W. E. & Chesnut, R. Y. (1981). Partial characterization of radiolabelled antigens from adult Schistosoma haematobium. Journal of Parasitology 67, 589–91.Google Scholar
Higashi, G. I., Kreiner, P. W., Keirns, J. J. & Bitensky, M. W. (1973). Adenosine 3′,5′-cyclic monophosphate in Schistosoma mansoni. Life Sciences 13, 1211–20.Google Scholar
Hill, B., Kilsby, J., Rogerson, G. W., McIntosh, R. T. & Ginger, C. D. (1981). The enzymes of pyrimidine biosynthesis in a range of parasitic protozoa and helminths. Molecular and Biochemical Parasitology 2, 123–34.Google Scholar
Hillman, G. R., Chu, S. H. & Dotson, M. J. (1980). Effects of dansylated acetyl choline analogues on Schistosoma mansoni. Journal of Pharmaceutical Sciences 69, 516–20.Google Scholar
Hillman, G. R. & Gibler, W. B. (1975). Acetylcholine receptors in Schistosoma mansoni: visualization and blockade by hycanthone. Biochemical Pharmacology 24, 1911–14.Google Scholar
Hillman, G. R., Gibler, W. B. & Anderson, J. B. (1977). Comparative effects of hycanthone in Schistosoma mansoni and Schistosoma japonicum. American Journal of Tropical Medicine and Hygiene 26, 238–42.Google Scholar
Hillman, G. R., Gibler, A. M. & Anderson, J. W. (1978). Scanning microfluorimetric studies of anticholinergic drugs in Schistosoma mansoni. Journal of Pharmacology and Experimental Therapeutics 207, 992–7.Google Scholar
Hillman, G. R., Gibler, W. B. & Chu, S.-H. (1976). Fluorescent probes of acetylcholine binding sites-indicators of drug action in Schistosoma mansoni. Biochemical Pharmacology 25, 2529–35.CrossRefGoogle ScholarPubMed
Hillman, G. R., Olsen, N. N. & Senft, A. W. (1974). Effect of methysergide and dihydroergotamine on Schistosoma mansoni. Journal of Pharmacology and Experimental Therapeutics 188, 529–35.Google Scholar
Hillman, G. R. & Senft, A. W. (1973). Schistosome motility measurements: response to drugs. Journal of Pharmacology and Experimental Therapeutics 185, 177–84.Google ScholarPubMed
Hillman, G. R. & Senft, A. W. (1975). Anticholinergic properties of the antischistosomal drug hycanthone. American Journal of Tropical Medicine and Hygiene 24, 827–34.Google Scholar
Hillman, G. R., Senft, A. W. & Gibler, W. B. (1978). The mode of action of hycanthone revisited. Journal of Parasitology 64, 754–6.Google Scholar
Hillyer, G. V. (1974). Buoyant density and thermal denaturation profiles of schistosome DNA. Journal of Parasitology 60, 725–7.Google Scholar
Hockley, D. J. & McLaren, D. J. (1973). Schistosoma mansoni: changes in the outer membrane of the tegument during development from cercaria to adult worm. International Journal for Parasitology 3, 13–25.Google Scholar
Homewood, C. A., Jewsbury, J. M. & Chance, M. L. (1972). The pigment formed during haemoglobin digestion by malarial and schistosomal parasites. Comparative Biochemistry and Physiology 43B, 517–23.Google Scholar
Howells, R. E., Gerken, S. E., Ramalho-Pinto, F. J., Kawazoe, U., Gazzinelli, G. & Pellegrino, J. (1975). Schistosoma mansoni: tail loss in relation to permeability changes during cercaria-schistosomulum transformation. Parasitology 71, 9–18.CrossRefGoogle ScholarPubMed
Huang, T.-Y. (1980). The energy metabolism of Schistosoma japonicum. International Journal of Biochemistry 12, 457–64.Google Scholar
Huang, T.-Y. (1981). Search for antischistosomal drugs on the basis of biochemistry of schistosomes. Archives Pharmaceutical Chemistry and Scientific Education 9, 1–24.Google Scholar
Hulbert, P. B., Bueding, E. & Hartman, P. E. (1974). Hycanthone analogues: dissociation of mutagenic effects from antischistosomal effects. Science 186, 647–8.Google Scholar
Isseroff, H. (1980). The enzymes of proline biosynthesis in Fasciola and Schistosoma and the possible role of proline in fascioliasis and schistosomiasis. Federation of European Biochemical Societies, Proceedings 61, 303–14.Google Scholar
Isseroff, H., Bonta, C. Y. & Levy, M. G. (1972). Monosaccharide absorption by Schistosoma mansoni - I. Kinetic characteristics. Comparative Biochemistry and Physiology 43A, 849–58.Google Scholar
Isseroff, H., Ertel, J. C. & Levy, M. G. (1976). Absorption of amino acids by Schistosoma mansoni. Comparative Biochemistry and Physiology 54B, 125–33.Google Scholar
Jaffe, J. J., Doremus, H. M., Dunsford, H. A., Kammerer, W. S. & Meymarian, E. (1973). Antischistosomal activity of tubericidin in monkeys. American Journal of Tropical Medicine and Hygiene 22, 62–72.Google Scholar
Jaffe, J. J., Doremus, H. M., Dunsford, H. A. & Meymarian, E. (1975). Treatment of schistosomiasis mansoni and japonica in baboons with tubericidin given by direct intravenous injection. American Journal of Tropical Medicine and Hygiene 24, 835–42.Google Scholar
Jaffe, J. J., McCormack, J. J. & Meymarian, E. (1972). Comparative properties of schistosomal and filarial dihydrofolate reductases. Biochemical Pharmacology 21, 719–31.Google Scholar
James, C., Webbe, G. & Preston, J. M. (1972). A comparison of the susceptibility to metrifonate of Schistosoma haematobium, S. mattheei and S. mansoni in hamsters. Annals of Tropical Medicine and Parasitology 66, 467–74.Google Scholar
Jansma, W. B., Rogers, S. H., Liu, C. L. & Bueding, E. (1977). Experimentally produced resistance of Schistosoma mansoni to hycanthone. American Journal of Tropical Medicine and Hygiene 26, 926–36.Google Scholar
Kasschau, M. R. & Mansour, T. E. (1982). Adenylate cyclase in adults and cercariae of Schistosoma mansoni. Molecular and Biochemical Parasitology 5, 107–16.Google Scholar
Kemp, W. M., Damian, R. T. & Greene, N. D. (1976 a). Immunocytochemical localization of IgG on adult Schistosoma mansoni tegumental surfaces. Journal of Parasitology 62, 830–2.Google Scholar
Kemp, W. M., Brown, P. R., Merritt, S. C. & Miller, R. E. (1980). Tegument associated antigen modulation by adult Schistosoma mansoni. Journal of Immunology 124, 806–11.Google Scholar
Kemp, W. M., Damian, R. T., Greene, N. D. & Lushbaugh, W. B. (1976 b). Immunocytochemical localization of mouse alpha 2-macroglobulin-like antigenic determinants on Schistosoma mansoni adults. Journal of Parasitology 62, 413–19.Google Scholar
Kemp, W. M., Merritt, S. C., Bogucki, M. S., Rosier, J. G. & Seed, J. R. (1977). Evidence for absorption of heterospecific host immunoglobulin on the tegument of Schistosoma mansoni. Journal of Immunology 119, 1849–54.Google Scholar
Kemp, W. M., Merritt, S. C. & Rosier, J. G. (1978). Schistosoma mansoni: identification of immunoglobulins associated with the tegument of adult parasites from mice. Experimental Parsitology 45, 81–7.Google Scholar
Kim, R. A., Lukacs, J., Tanaka, T. D. & MacInnis, A. J. (1981). Effects of hycanthone and praziquantel on monoamine oxidase and cholinesterases in Schistosoma mansoni. Journal of Parasitology 67, 20–3.Google Scholar
Kohn, A., Lopez-Alvarez, M. L. & Katz, N. (1982). Transmission and scanning electron microscopical studies in the tegument of male Schistosoma mansoni after oxamniquine treatment. Annales Parasitologie 57, 285–91.Google ScholarPubMed
Kusel, J. A. & MacKenzie, P. E. (1975). The measurement of the relative turnover rates of proteins of the surface membranes and other fractions of Schistosoma mansoni in culture. Parasitology 71, 261–73.Google Scholar
Kusel, J. R., MacKenzie, P. E. & McLaren, D. J. (1975). The release of membrane antigens into culture by adult Schistosoma mansoni. Parasitology 71, 247–59.Google Scholar
Kusel, J. R., Stones, L. & Harnett, W. (1981). The use of membrane-active compounds to examine the structure of the surface membrane of Schistosoma mansoni. Bioscience Reports 1, 253–61.Google Scholar
Kusel, J. R., Stones, L. & Harnett, W. (1982 a). The effects of retinol (vitamin A alcohol) and various non-ionic detergents on the surfaces of schistosomula and adult Schistosoma mansoni. Molecular and Biochemical Parasitology 5, 147–63.Google Scholar
Kusel, J. R., Stones, L. & Harnett, W. (1982 b). The interaction of membrane-active compounds with the surface of schistosomula and adult Schistosoma mansoni. Biophysical Journal 37, 32–4.Google Scholar
Kusel, J. R., Stones, L. & Tetley, T. (1980). Damage to surface membrane of Schistosoma mansoni by pristane (2, 6, 10, 14 tetramethyl pentadecane) and other hydrophobic compounds. Parasitology 80, 83–94.Google ScholarPubMed
Landsperger, W. J., Stirewalt, M. A. & Dresden, M. H. (1982). Purification and properties of a proteolytic enzyme from the cercariae of the human trematode parasite Schistosoma mansoni. Biochemical Journal 201, 137–44.Google Scholar
Lawrence, J. D. (1973). The ingestion of red blood cells by Schistosoma mansoni. Journal of Parasitology 59, 60–3.Google Scholar
Lawson, J. R. & Wilson, R. A. (1980 a). The survival of the cercariae of Schistosoma mansoni in relation to water temperature and glycogen utilization. Parasitology 81, 337–48.Google Scholar
Lawson, J. R. & Wilson, R. A. (1980 b). Metabolic changes associated with the migration of the schistosomulum of Schistosoma mansoni in the mammal host. Parasitology 81, 325–36.Google Scholar
Levy, M. G. & Read, C. P. (1975 a). Purine and pyrimidine transport in Schistosoma mansoni. Journal of Parasitology 61, 627–32.Google Scholar
Levy, M. G. & Read, C. P. (1975 b). Relation of tegumentary phosphohydrolase to purine and pyrimidine transport in Schistosoma mansoni. Journal of Parasitology 61, 648–56.Google Scholar
Lee, H. G. (1972). Aspects of the effect of thioxanthone on Schistosoma mansoni in mice and in vitro. Bulletin of the World Health Organization 46, 397–402.Google Scholar
Lichtenberg, F. V., Bawden, M. P. & Shealey, S. H. (1974). Origin of circulating antigen from the schistosome gut. An immunofluorescent study. American Journal of Tropical Medicine and Hygiene 23, 1088–91.Google Scholar
Linder, E. & Huldt, G. (1982). Distribution of exposed and hidden carbohydrates of Schistosoma mansoni adult worms demonstrated by selective binding of fluorochrome-conjugated lectins. Parasitology 85, 503–9.Google Scholar
Long, G. W., Lewart, R. M. & Pelley, R. P. (1981 a). Fractionation of Schistosoma japonicum soluble egg antigen glycoproteins by hydrophobic interaction chromatography. Infection and Immunity 34, 397–406.Google Scholar
Long, G. W., Lewert, R. M. & Pelley, R. P. (1981 b). Characterization of the glycoprotein antigens which mediate the Schistosoma japonicum circumoval precipitin reaction. Infection and Immunity 34, 389–96.Google Scholar
Lukacs, J., Tanaka, R. D., Kim, R. A. & MacInnis, A. J. (1980). Development of a cell-free protein-synthesizing system from Schistosoma mansoni and a comparison of the effects of hycanthone and praziquantel on this system. Journal of Parasitology 66, 424–7.Google Scholar
Machado, C. R. S., Machado, A. B. M. & Pellegrino, J. (1972). Catecholamine-containing neurons in Schistosoma mansoni. Zeitschrift für Zellforschung und microskopische Anatomie Abteiling histochemie 124, 230–7.Google Scholar
Mahon, R. J. & Shiff, C. J. (1978). Electrophoresis to distinguish Schistosoma haematobium and S. mattheei cercariae emerging from Bulinus snails. Journal of Parasitology 64, 372–3.Google Scholar
Mattoccia, L. P. & Cioli, D. (1983). Effect of hycanthone administered in vivo upon the incorporation of radioactive percursors into macromolecules of Schistosoma mansoni. Molecular and Biochemical Parasitology 8, 99–107.Google Scholar
Mattoccia, L. P., Lelli, A. & Cioli, D. (1981). Effect of hycanthone on Schistosoma mansoni macromolecular synthesis in vitro. Molecular and Biochemical Parasitology 2, 295–307.Google Scholar
Mazinque, C., Camus, D., Dessaint, J.-P., Capron, M. & Capron, M. (1980). In vitro and in vivo inhibition of mast cell degranulation by a factor from Schistosoma mansoni. International Archives of Allergy and Applied Immunology 63, 178–89.Google Scholar
McDiarmid, S. S., Dean, L. L. & Podesta, R. B. (1983). Sequential removal of outer bilayer and apical plasma membrane from the surface epithelial syncytium of Schistosoma mansoni. Molecular and Biochemical Parasitology 7, 141–57.Google Scholar
McDiarmid, S. S., Podesta, R. B. & Rahman, S. M. (1982). Preparation and partial characterization of a multilamella body fraction from Schistosoma mansoni. Molecular and Biochemical Parasitology 5, 93–105.Google Scholar
McGuinness, T. B. & Kemp, W. M. (1981). Schistosoma mansoni: a complement dependent receptor on adult male parasites. Experimental Parasitology 61, 236–42.Google Scholar
McKerrow, K. H. & Jeong, K. H. (1982). Schistosoma mansoni: Cercariae degradation of a radioactively labeled collagen gel. Experimental Parasitology 53, 249–54.Google Scholar
Mehlhorn, H., Becker, B., Andrews, P., Thomas, H. & Frenkel, J. K. (1981). In vivo and in vitro experiments on the effect of praziquantel on Schistosoma mansoni. Arzneimittel-Forschung 31, 544.Google Scholar
Mehlhorn, H., Frenkel, J. K., Andrews, P. & Thomas, H. (1982). Light and electron microscopic studies on Schistosoma mansoni granulomas of mouse livers following treatment with praziquantel. Tropenmedizin and Parasitologie 33, 229–39.Google Scholar
Mellin, T. N., Busch, R. D., Wang, C. C. & Kath, G. (1983). Neuropharmacology of the parasitic trematode Schistosoma mansoni. American Journal of Tropical Medicine and Hygiene 32, 83–93.Google Scholar
Miech, R. P., Senft, A. W. & Senft, D. G. (1975). Pathways of nucleotide metabolism in Schistosoma mansoni - VI. Adenosine phosphorylase. Biochemical Pharmacology 24, 407–11.Google Scholar
Minard, P., Murrell, K. D. & Stirewalt, M. A. (1977). Proteolytic, antigenic and immunogenic properties of Schistosoma mansomi cercarial secretion material. American Journal of Tropical Medicine and Hygiene 26, 491–9.Google Scholar
Mitchell, G. F., Cruise, K. M., Garcia, E. G. & Anders, R. F. (1981). Hybridoma-derived antibody with immunodiagnostic potential for schistosomiasis japonica. Proceedings of the National Academy of Sciences. USA 78, 3165–9.Google Scholar
Murrell, K. D., Taylor, D. W., Vanniee, W. E. & Dean, D. A. (1978). Schistosoma mansoni: analysis of surface membrane carbohydrates using lectins. Experimental Parasitology 46, 247–55.Google Scholar
Murrell, K. D., Vannier, W. E. & Ahmed, A. (1974). Schistosoma mansoni: antigenic heterogeneity ofexcretions and secretions. Experimental Parasitology 36, 316–30.Google Scholar
Nagai, Y., Gazztnelli, G., Moraes, G. W.O. De & Pelleorino, J. (1977). Protein synthesis during cercaria-schistosomulum transformation and early development of the Schistosoma mansoni larvae. Comparative Biochemistry and Physiology 57B, 27–30.Google Scholar
Nash, T. E. (1974). Localization of the circulating antigen within the gut of Schistosonia mansoni. American Journal of Tropical Medicine and Hygiene 23, 1085–7.Google Scholar
Nash, T. E. (1979). Schistosoma mansoni: Pattern of release of secretory products. Experimental Parasitology 48, 92–9.Google Scholar
Nash, T. E., Nasiir-Ud-Din, & Jeanloz, R. W. (1977). Further purification and characterization of a circulating antigen in schistosomiasis. Journal of Immunology 119, 1627–33.Google Scholar
Nash, T. E., Prescott, B. & Neva, F. A. (1974). The characteristics of a circulating antigen in schistosomiasis. Journal of Immunology 112, 1500–7.Google Scholar
Neame, K. D., Homewood, C. A., Marshall, I. & Jewsbury, J. M. (1978) The effect of hycanthone on nucleic acid synthesis by Schistosoma mansoni. Annals of Tropical Medicine and Parasitology 72, 587–8.Google Scholar
Nechay, B. R., Hillman, O. R. & Dotson, M. J. (1980). Properties and drug sensitivity of adenosine triphosphatases from Schistosoma mansoni. Journal of Parasitology 66, 596–600.Google Scholar
Nirde, P. L., Torpier, G., Reggi, M. L. De & Capron, A. (1983). Ecdysone and 20-hydroxyecdysone: new hormones for the human parasite Schistosonia mansomi. FEBS Letters 151, 223–7.Google Scholar
Norden, A. P., Aronstein, W. S. & Strand, M. (1982). Schistosoma mansoni: identification, characterization, and purification of the spine glycoprotein by monoclonal antibody. Experi mental Parasitology 54, 432–42.Google Scholar
Oaks, J. A., Cain, G. D., Mower, P. A. & Raj, R. K. (1981). Disruption and removal of the tegument from Schistosoma mansoni with Triton X-100. Journal of Parasitology 67, 761–75.Google Scholar
Otubanjo, O. A. (1981). Schistosoma mamsomi: astiban-induced damage to tegument and the male reproductive system. Experimental Parasitology 52, 161–70.Google Scholar
Ouaissi, M. A., Aurtault, C., Santoro, F. & Capron, A. (1981). Interaction between Schistosoma mansoni and the complement system: role of IgG Fc peptides in the activation of the classical pathway by schistosomula. Journal of Immunology 127, 1556–9.Google Scholar
Ouaissi, M. A., Santoro, F. & Capron, A. (1980). Interaction between Schistosoma mansoni and the complement system. Receptors for C3b on cercariae and schistosomula. Immunology Letters 1, 197–201.Google Scholar
Owhashi, M. & Ishii, A. (1981). Fractionation and characterization of allergens extracted from eggs of Schistosonia japonicum. International Archives of Allergy and Applied Immunology 64, 146–56.Google Scholar
Oyerinde, J. P. O. (1976). The effects of I: 7 bis (p-aminophenoxy) heptane on adult Schistosoma mansoni in mice. Nigerian Medical Journal 6, 392–7.Google Scholar
Pax, R., Bennett, J. L. & Fetterer, R. (1978). A benzodiazepine derivative and praziquantel: effects on musculature of Schistosoma mansoni and S. japonicum. Archives of Pharmacology 304, 309–15.Google Scholar
Pax, R., Fetterer, R. & Bennett, J. L. (1979). Effects of fluoxetine and imipramine on male Schistosonia mansoni. Comparative Biochemistry and Physiology 64C, 123–7.Google Scholar
Pelley, R. P. & Pelley, R. J. (1976). S. Inansoni soluble egg antigens - IV. Biochemistry and immunochemistry of major serological antigens with particular emphasis on MSA. In Biochemistry of Parasites and Host—Parasite Relationships (ed. van den Bossche, H.), pp. 283–290. Amsterdam: Elsevier/North Holland Biomedical Press.Google Scholar
Pelley, R. P., Pelley, R. J., Hamburger, J., Peters, P. A. & Warren, K. S. (1976). Schistosoma mansoni soluble egg antigens. I. Identification and purification of three major antigens, and the employment of radioimmunoassay for their further characterization. Journal of Immunology 117, 1553–60.Google Scholar
Pijkeren, T. A. Van, Tavares, C. A. P. & Gazzinelli, G. (1982). Schistosorna mansoni; ability of Con A to protect in vitro mechanically transformed schistosomula against the lethal effect of immune serum plus complement. Parasitology 84, 239–52.Google Scholar
Podesta, R. B. & McDiarmjd, S. S. (1982). Enrichment and partial enzyme characterization of ATPase activity associated with the outward-facing membrane complex and inward-facing membrane of the surface epithelial syncytium of Schistosoma mansoni. Molecular and Biochemical Parasitology 6, 225–35.Google Scholar
Podesta, R. B. & Dean, L. L. (1982 a). A method for determining nonelectrolyte uptake by adult Schistosoma mansoni using compartmental analysis of hexosefluxes. Molecular and Biochemical Parasitology 5, 345–52.Google Scholar
Podesta, R. B. & Dean, L. L. (1982 b). Uptake of galactose by the epithelial syncytium of Schistosorna mansoni. Molecular and Biochemical Parasitology 5, 353–60.Google Scholar
Popiel, I. & Erasmus, D. A. (1981 a). Schistosoma mansoni: changes in the rate of tyrosine uptake by unisexual females after stimulation by males and male extracts. Journal of Helminthology 55, 33–7.Google Scholar
Popiel, I. & Erasmus, D. A. (1981 b). Schistosoma mansoni: niridazole-inducecl damage to the vitelline gland. Experimental Parasitology 52, 35–48.Google Scholar
Rahman, M. S. & Podesta, R. B. (1982). Phosphatidate phosphatase activity in the blood fluke, Schistosorna mansoni. Molecular and Biochemical Parasitology 6, 331–4.Google Scholar
Ramalho-Pinto, F. J., Gazzinelli, G., Howells, H. E. & Pellegrino, J. (1975). Factors affecting surface changes in intact cercariae and cercarial bodies of Schistosoma mansoni. Parasitology 71, 19–25.Google Scholar
Ramasamy, R. (1979). Surface proteins of schistosomula and cercariae of Schistosoma mansoni. International Journal for Parasitology 9, 491–3.Google Scholar
Reiner, E. (1981). Esterases in schistosomes: reaction with substrates and inhibitors. Acta Pharmacologica et Toxicologica 49, Suppl. 5, 72–8.Google Scholar
Reiner, E., Simeon, V. & Skrinjaric-Spoljar, M. (1980). Hydrolysis of 0,0-dimethyl- 2,2-dichiorovinyl phosphate (DDVP) by esterases in parasitic helminths, and in vertebrate plasma and erythrocytes. Comparative Biochemistry and Physiology 66C, 149–52.Google Scholar
Rogers, S. H. (1976). Schistosomatiuin douthitti: carbohydrate metabolism in adults. Experi mental Parasitology 40, 397–405.Google Scholar
Rogers, S. H. & Burning, E. (1975). Anatomical localization of glucose uptake by Schistosoma mansoni adults. International Journal for Parasitology 5, 369–71.Google Scholar
Ross, A. F. & Jaffe, J. J. (1972). Effects of tubericidin and its ribonucleotides on various metabolic pathways in Schistosoma mansoni. Biochemical Pharmacology 21, 3059–69.Google Scholar
Ross, G. C., Southgate, V. R. & Knowles, H. J. (1978). Observations on some isoenzymes of strains of Schistosoma bovis, S. niattheei, S. margrebowiei and S. leiperi. Zeitschrift für Parasitenkunde 57, 49–56.Google Scholar
Rotmans, J. P. (1978). Schistosonia mansoni: purification and characterization of malate dehydrogenases. Experimental Parasitology 46, 31–48.Google Scholar
Rotmans, J. P., Voort, M. J. Van Der, Looze, M., Mooij, G. W. & Deelder, A. M. (1981). Schistosoma mansoni: Characterization of antigens in excretions and secretions. Experimental Parasitology 52, 171–82.Google Scholar
Rousseaijx-Prevost, R., Dessaint, J.-P. & Capron, A. (1982). Potentiated reagin response to ovalbumin in Schistosoma mansoni-infected rats and rats treated with a soluble metabolic product from adult worms. International Archives of Allergy and Applied hnnsunology 67, 187–90.Google Scholar
Ruff, M. D., Davis, C. M. & Werner, J. K. (1973). Schistosoma japonicum: discelectrophoretic protein patterns of the Japanese, Philippine, and Formosan strains. Experimental Parasitology 33, 437–46.CrossRefGoogle Scholar
Rumjanek, F. D. (1980 a). Biochemical adaptation during Schistosoma mansoni infection. in The Host Invader Interplay (ed. Van den Bossche, H.), pp. 139–142. Amsterdam: Elseveir/North-Holland Biomedical Press.Google Scholar
Rumjanek, F. D. (1980 b). The schistosome mannolipid. Comparative Bioche and Physiology 65B, 345–9.Google Scholar
Rumjanek, F. D., Broomfield, K. E. & Smtthers, S. R. (1979). Schistosoma mansoni: glycosyl transferase activity and the carbohydrate composition of the tegument. Experimental Parasitology 47, 24–35.Google Scholar
Rumjanex, F. D. & Cesari, I. M. (1981). The effect of indomethacin on lipid metabolism of Schistosoma mansoni. Biochemical Pharmacology 30, 3337–40.Google Scholar
Rumjanek, F. P. & Curiel, M. (1983). The occurrence of proteolipid antigens in Schistosoma mansoni. Molecular and Biochemical Parasitoloqy 7, 183–95.Google Scholar
Rumjanek, F. D. & McLaren, P. J. (1981). Schistosoma mansoni: modulation of schistosomular lipid composition by serum. Molecular and Biochemical Parasitology 3, 239–52.Google Scholar
Rumjanek, F. D. & Simpson, A. J. G. (1980). The incorporation and utilization of radiolabelled lipids by adult Schistosoma mansoni in vitro. Molecular and Biochemical Parasitology 1, 31–44.Google Scholar
Rumjanek, F. P. & Smithers, S. R. (1978). Mannosyl transferase activity in homogenates of adult Schistosoma mansoni. Parasitology 77, 75–86.Google Scholar
Ruppel, A. & Cioli, D. (1977). A comparative analysis of various developmental stages of Schistosoma mansoni with respect to their protein composition. Parasitology 75, 339–43.Google Scholar
Samuelson, J. C. & Caulfield, J. P. (1982). Loss of covalently labelled glycoproteins and glycolipids from the surface of newly transformed schistosomula of Schistosoma mansoni. Journal of Cell Biology 94, 363–9.Google Scholar
Samuelson, J. C., Caulfield, J. P. & David, J. R. (1982). Schistosomula of Schistosonla mansoni clear concanavalin A from their surface by sloughing. Journal of Cell Biology 94, 355–62.Google Scholar
Samuelson, J. C., Sher, A. & Caulfield, J. P. (1980). Newly transformed schistosomula spontaneously lose surface antigens and C3 acceptor sites during culture. Journal of Immuno logy 124, 2055–7.Google Scholar
Sano, M. & Ishii, A. (1978). Experimental studies of schistosomal pigment from Schistosoma japonicum. Experientia 35, 472–3.Google Scholar
Schiller, E. L., Bueding, E., Turner, V. M. & Fisher, J. (1975). Aerobic and anaerobic carbohydrate metabolism and egg production of Schistosoma mansoni in vitro. Journal of Parasitology 61, 385–9.Google Scholar
Seed, J. L. & Bennett, J. L. (1980). Schistosoma manson.i: phenol oxidases role in eggshell formation. Experimental Parasitology 49, 430–41.Google Scholar
Seed, J. L., Boff, M. & Bennett, J. L. (1978). Phenol oxiclase activity: induction in female schistosomes by in vitro incubation. Journal of Parasitology 64, 283–9.Google Scholar
Semeyn, P. R., Pax, R. A. & Bennett, J. L. (1982). Surface electrical activity from Schistosorna mansoni: a sensitive measure of drug action. Journal of Parasitology 68, 353–62.Google Scholar
Senft, A. W. (1976). Observations on the physiology of the gut of Schistosoma mansoni. In Biochemistry of Parasites and Host—Parasite Relationships (ed. Van den Bossche, H.), pp. 335–342. Amsterdam: Elsevier/North-Holland Biomedical Press.Google Scholar
Seeft, A. W. (1977). Recent advances in the physiology of schistosomes special working group on Schistosomiasis, W.H.O. Geneva.Google Scholar
Senft, A. W. & Crabtree, G. W. (1977). Pathways of nucleotide metabolism in Schistosoma mansoni — VII. Inhibition of adenine and guanine nucleotide synthesis by purine analogs in intact worms. Biochemical Pharmacology 26, 1847–55.Google Scholar
Senft, A. W., Crabtree, G. W., Agarwal, K. C., Scholar, E. M., Agarwal, R. P. & Parks, R. E. Jr. (1973 b). Pathways of nucleotide metabolism in Schistosoma niansoni — ITT. Iclentifi cation of enzymes in cell free extracts. Biochemical Pharmacology 22, 449–58.Google Scholar
Senft, A. W., Goldberg, M. W. & Byram, J. E. (1981). Helnoglobinolytic activity of serum in mice infected with Schistosoma mansoni. American Journal of Tropical Medicine and Hygiene 271. 30, 96–101.Google Scholar
Senft, A. W., Goldberg, M. W., Byram, J. E. & Jaivin, J. S. (1980). Schistosomal hemoglobinase: nature of the protease and implications for the host. In The Host Invader Interplay (ed. Van den Bossche, H.), pp. 427–442. Amsterdam: Elsevier/North-Hollancl Biomedical Press.Google Scholar
Senft, A. W. & Hillman, G. R. (1973). Effect of hycanthone, niridazole, and antimony tartrate on schistosome motility. American Journal of Tropical Medicine and Hygiene 22, 734–42.Google Scholar
Senft, A. W. & Maddison, S. E. (1975). Hypersensitivity to parasite proteolytic enzyme in schistosoma mansoni. American Journal of Tropical Medicine and Hygiene 24, 83–9.Google Scholar
Senft, A. W., Miech, R. P., Brown, P. R. & Senft, D. G. (1972). Purine metabolism in Schistosoma mansoni. International Journal for Parasitology 2, 249–60.Google Scholar
Senft, A. W., Senft, D. G., Hillman, G. R., Polk, D. & Kryger, S. (1976). Influence of hycanthone on morphology and serotonin uptake of Schistosoma mansoni. American Journal of Tropical Medicine and Hygiene 25, 832–40.Google Scholar
Senft, A. W., Senft, D. G. & Miech, R. P. (1973 a). Pathways of nucleotide metabolism in Schistosoma mansoni — II. Disposition of adenosine by whole worms. Biochemical Pharmacology 22, 437–47.Google Scholar
Senft, A. W., Weltman, J. K., Goldgraber, M. B., Egyud, L. G. & Kuntz, R. E. (1979). Species specificity of the immediate hypersensitivity to schistosomal proteolytic enzyme. Parasite Immunology 1, 79–89.Google Scholar
Shah, J. & Ramasay, R. (1982). Surface antigens on cercariae, schistosomula and adult worms of Schistosoma mansoni. international Journal for Parasitology 12, 451–61.Google Scholar
Shapiro, T. A. & Talalay, P. (1982 a). Schistosoma mansoni: inhibition of glucosephosphate isomerase and glycolysis by sugar phosphates. Experimental Parasitology 54, 196–201.Google Scholar
Shapiro, T. A. & Talalay, P. (1982 b). Sehistosoma mansoni: mechanisms in regulation of glycolysis. Experimental Parasitology 54, 379–80.Google Scholar
Shaw, J. R. & Erasmus, D. A. (1977). Schistosoma mansoni: differential cell death associated with in vitro culture and treatment with Astiban (Roche). Parasitology 75, 101–9.Google Scholar
Shaw, M. R. & Erasmus, D. A. (1982). Schistosoma mansoni: effect of praziquantel on the ultrastructure of worms in vivo. Transactions of the Royal Society of Tropical Medicine and Hygiene 76, 528.Google Scholar
Shaw, M. K., Davies, T. W. & Erasmus, D. A. (1982). The demonstration of calcium in the axonal granules of the peripheral nervous system of male Schistosorna mansoni by X-ray microanalysis. Cell and Tissue Research 222, 597–604.Google Scholar
Shaw, J. R., Marshall, I. & Erasmus, D. A. (1977). Schistosoma mansoni: in vitro stimulation of vitelline cell development by extracts of male worms. Experimental Parasitology 42, 14–20.Google Scholar
Sher, A. (1976). Complement-dependent adherence of mast cells to schistosomula. Nature, London 263, 334–6.Google Scholar
Sher, A., Hall, B. F. & Vadas, M. A. (1978). Acquisition of murine major histocompatability complex genes products by schistosomula of Schistosoma mansoni. Journal of Experimental Medicine 148, 46–50.Google Scholar
Simpson, A. J. C., Cesari, I. M., Evans, W. H. & Smtthers, S. R. (1980). Isolation and characterization of the tegumental outer membrane of adult Schistosoma mansoni. In The Host Invader interplay (ed. Van den Bossche, H.), pp. 135–138. Amsterdam: Elsevier/North-Holland Biomedical Press.Google Scholar
Simpson, A. J. G. & McLaren, D. J. (1982). Schistosoma mansoni: tegumental damage as a consequence of lectin binding. Experimental Parasitology 53, 105–16.Google Scholar
Simpson, A. J. G., Correa-Oliveira, R., Smithers, S. R. & Sher, A. (1983). The exposed carbohydrates of schistosomula of Schistosoma mansoni and their modification during maturation in vivo. Molecular and Biochemical Parasitology 8, 191–205.Google Scholar
Simpson, A. J. G., Rumjanek, F. D., Payares, G. & Evans, W. H. (1981 a). Glycosyl transferase activities are associated with the surface membrane in adult Schistosoma mansoni. Molecular and Biochemical Parasitology 4, 107–15.Google Scholar
Simpson, A. J. G., Schryer, M. D., Cesari, I. M., Evans, W. H. & Smithers, S. R. (1981 b). Isolation and partial characterization of the tegumental outer membrane of adult Schistosoma mansoni. Parasitology 83, 163–77.Google Scholar
Simpson, A. J. G. & Smithers, S. R. (1980). Characterization of the exposed carbohydrates on the surface membrane of adult Schistosoma mansoni by analysis of lectin binding. Parasitology 81, 1–15.Google Scholar
Simpson, A. J. G., Sher, A. & McCutchan, T. F. (1982). The genome of Schistosoma mansoni: isolation of DNA, its size, bases and repetitive sequences. Molecular and Biochemical Parasitology 6, 125–37.Google Scholar
Smith, M. A. (1974). Radioassays for the proteolytic enzyme secreted by living eggs of Schistosoma mansoni. international Journal of Parasitology 4, 681–3.Google Scholar
Smith, M. A., Clego, J. A., Snary, D. & Trejdosiewicz, A. J. (1983). Passive immunization of mice against Schistosoina mansoni with an 1gM monoclonal antibody. Parasitology 84, 83–91.Google Scholar
Smith, T. M. & Brown, J. N. (1977 a). Tricarboxylic acid cycle enzyme activities in adult Schistosoma mansoni and Schi stosoma japonicum. Transactions of the Royal Society of Tropical Medicine and Hygiene 71, 329–30.Google Scholar
Smith, T. M., Doughty, B. L. & Brown, J. N. (1977). Fatty acid and lipid class composition of Schistosoma japonicum eggs. Comparative Biochemistry and Physiology 57B, 59–63.Google Scholar
Snary, D., Smith, M. A. & Clegg, J. A. (1980). Surface proteins of Schistosoma mansoni and their expression during morphogenesis. European Journal of Immunology 10, 573–5.Google Scholar
Stegman, R. J., Senft, A. W., Brown, P. R. & Parks, R. E. Jr. (1973). Pathways of nucleotide metabolism in Schistosoma mansoni — IV. Incorporation of adenosine analogs in vitro. Biochemical Pharmacology 22, 459–68.Google Scholar
Stirewalt, M. (1978). Quantitative collection and proteolytic activity of preacetabular gland enzyme(s) of cercariae of Schistosoma mansoni. American Journal of Tropical Medicine and Hygiene 27, 548–53.Google Scholar
Stirewalt, M. A. & Austin, B. E. (1973). Collection of a secreted protease from the pre acetabular glands of cercariae of Schistosoma mansoni. Journal of Parasitology 59, 741–3.Google Scholar
Stirnholm, R. L. & Warren, K. S. (1974). Schistosoma mansoni: utilization of exogenous metabolites by eggs in vitro. Experimental Parasitology 36, 222–32.Google Scholar
Strand, M., McMillan, A. & Pan, X.-P. (1982). Schistosorna mansoni: reactivity with infected human sera and monoclonal antibody characterization of a glycoprotein in different develop mental stages. Experimental Parasitology 54, 145–56.Google Scholar
Taylor, D. W. & Butterworth, A. E. (1982). Monoclonal antibodies against surface antigens of schistosomula of Schistosoma mansoni. Parasitology 84, 65–82.0Google Scholar
Taylor, D. W., Hayunga, E. G. & Vannier, W. E. (1981). Surface antigens of Schistosoma mansoni. Molecular and Biochemical Parasitology 3, 157–68.Google Scholar
Tenniswood, M. P. R. & Simpson, A. J. G. (1982). The extraction, characterization and in vitro translation of RNA from adult Schistosoma mansoni. Parasitology 84, 253–61.Google Scholar
Tomosky, T. K., Bennett, J. L. & Bueding, E. (1974). Tryptaminergic and dopaminergic responses of Schistosoma mansoni. Journal of Pharnuicology and Experimental Therapeutics 190, 260–71.Google Scholar
Tomosky-Sykes, T. K. & Bueding, E. (1977). Effects of hycanthone on neuromuscular systems of Schistosoma mansoni. Journal of Parasitology 63, 259–66.Google Scholar
Torpier, G. & Capron, A. (1980 a). Differentiation and expression of surface antigens in relation with S. mansorti membrane structure. In The Host Invader Interplay (ed. Van den Bossche, H.), pp. 143–146. Amsterdam: Elsevier/North-Holland Biomedical Press.Google Scholar
Torpier, G. & Capron, A. (1980 b). Intramembrane particle movements associated with binding of lectins on Schistosoma mansoni surface. Journal of Ultrastructure Research 72, 325–35.CrossRefGoogle ScholarPubMed
Torpier, G., Capron, A. & Ouaissi, M. A. (1979). Receptor for IgG (Fc) and human 2-microglobulin on S. mansoni schistosomula. Nature, London 278, 447–9.Google Scholar
Torpier, G., Hirn, M., Nirde, P. De, Reggi, M. & Capron, A. (1982). Detection of ecdysteroids in the human trematode, Schistosoma mansoni. Parasitology 84, 123–30.Google Scholar
Tracy, J. W. & Mahmoud, A. A. F. (1982). Isolation of Schistosoma japonicum egg glycoprotein antigens which sensitize mice to lung granuloma formation and elicit an immediate hypersensitivity. American Journal of Tropical Medicine and Hygiene 31, 1201–12.Google Scholar
Tsang, V. C. W., Hubbard, W. J. & Damian, R. T. (1977). Coagulation factor XIIa (activated Hageman factor) inhibitor from adult Schistosoma mansoni. American Journal of Tropical Medicine and Hygiene 26, 243–7.Google Scholar
Tzeng, S. F., McKerrow, J. H., Jeong, K., Fukuyama, K. & Epstein, W. L. (1982). Partial purification and characterization of an inhibitor from newborn-rat epidermis with activity against the proteinase of Schistosoma mansoni cercariae. Biochemical Journal 207, 479–84.Google Scholar
Uglem, G. L. & Read, C. P. (1975). Sugar transport and metabolism in Schistosoma mansoni. Journal of Paravitology 61, 390–7.Google Scholar
Bossche, H. Van Den (1977). Recent advances in schistosome biochemistry. Special working group on Schistosomiasis, W.H.O. Geneva.Google Scholar
Bosscue, H. Van Den, Verhoeven, H., Vanparijs, O., Lauwers, H. & Thienpont, D. (1979). Closantel, a new antiparasitic hydrogen ionophore. Archives of International Physiology and Biochemistry 87, 851–2.Google Scholar
Egmond, J. G. Van, Deelder, A. M. & Daha, M. R. (1981). Schistosoma mansoni: complement activation by antigenic preparations. Experimental Paravitology 51, 188–94.Google Scholar
Voge, M. & Bueding, E. (1980). Schistosoma mansoni: tegumental surface alterations induced by subcurative doses of the schistosomicide amoscanate. Experimental Parasitology 50, 251–9.Google Scholar
Kruger, W. M. A. Von, Gazzinelli, G., Figueiredo, E. A. & Pellegrino, J. (1978). Oxygen uptake and lactate production by Schistosoma mansoni cercaria, cercarial body and tail, and schistosomule. Comparative Biochemistry and Physiology 60B, 41–6.Google Scholar
Walker, E. & Chappell, L. H. (1980). Schistosonia mansoni: comparison of the effects of cycloheximide and emetine on protein synthesis in adult worms. Comparative Biochemistry and Physiology 67C, 129–34.Google Scholar
Walker, E. & Chappell, L. IH. (1982). Schistosoma mansoni: in vitro uptake and incorporation of glycine by adult worms. Comparative Biochemistry and Physiology 73B, 385–92.Google Scholar
Warren, K. S. (1980). The immunopathology of schistosomiasis. In The Host Invader Interplay (ed. Van den Bossche, H.), pp. 371–380. Amsterdam: Elsevier/North-Holland Biomedical Press.Google Scholar
Watts, S. D. M. (1978). The effects of 1,7-bis (p-aminophenoxy) heptane (153C51) on glucose utilization by Schistosoma mansoni. Comparative Biochemistry and Physiology 60C, 109–14.Google Scholar
Watts, S. D. M., Orpin, A. & MacCormick, C. (1979). Lysosomes and tegument pathology in the chemotherapy of schistosomiasis with 1,7-bis (p-aminophenoxy) heptane (153C51). Parasitology 78, 287–94.Google Scholar
Willcookson, W. S., Ahmed, A. E. & Hillman, G. R. (1982). Schistosoma mansoni: species-selective response to N-chlorothyl-acetylcholine derivatives. Experimental Parasitology 56, 70–80.Google Scholar
Willcockson, W. S., Dotson, M. J., McAllister, P., Grim, S. O., Ahmed, A. E. & Hillman, G. R. (1982). Effects of phosphonium and chloroethylacetylcholine compounds on schistosome and vertebrate acetylcholinesterase. Comparative Biochemistry and Physiology 72C, 101–2.Google Scholar
Wilson, R. A. & Barnes, P. E. (1974). An in vitro investigation of dynamic processes occurring in the schistosome tegument, using compounds known to disrupt secretory processes. Parasitology 68, 259–70.Google Scholar
Wilson, H. A. & Barnes, P. E. (1977). The formation and turnover of the membranocalyx of the tegument of Schistosoma mansoni. Parasitology 74, 61–71.Google Scholar
Wilson, R. A. & Barnes, P. E. (1979). Synthesis of macromolecules by the epithelial surface of Schistosoma mansoni: an autoradiographic study. Parasitology 78, 295–310.Google Scholar
Wolde Nussie, E., Waa, J. Van De, Pax, R. A., Fetterer, R. & Bennett, J. L. (1982). Schistosoma mansoni: calcium efflux and effects of calcium -free media on responses of the adult male musculature to praziquantel and other agents inducing contraction. Experimental Parasitology 53, 270–8.Google Scholar
Woolhouse, N. M. (1979). Biochemical and pharmacological effects in relation to the mode of action of antischistosomal drugs. Biochemical Pharmacology 28, 2413–18.Google Scholar
Woolhouse, N. M. & Kaye, B. (1977). Uptake of [14C] oxamniquine by Schistosoma mansoni. Parasitology 75, 111–18.Google Scholar
Wright, E. P., Guthrie, C. D., Salim, D., Hilditch, T. J. O. & Das, P. K. (1982). Inhibition of lymphocyte activation by hatching fluid from Schistosoma manson eggs. Infection and Immunity 36, 419–22.Google Scholar
Wyler, J. & Tracy, J. W. (1982). Direct and indirect effects of soluble extracts of Schistosoma mansoni eggs on fibroblast proliferation in vitro. Infection and Immunity 38, 103–8.Google Scholar
Yarinsky, A., Drobeck, H. P., Freele, H., Wiland, J. & Gumaer, K. I. (1974). An 18-month study of the parasitologic and tumorigenic effects of hycanthone in Schistosoma mansoni infected and non-infected mice. Toxicology and Applied Pharmacology 27, 169–92.Google Scholar
Young, B. W. & Podesta, R. B. (1982). Major phospholipids and phosphatidylcholine synthesis in adult Schistosoma mansoni. Molecular and Biochemical Parasitology 5, 165–72.Google Scholar
Zoida, D. M. & Phillips, S. M. (1982). Monoclonal antibody-mediated protection against Schistosoma mansoni infection in mice. Journal of Immunology 129, 2326–8.Google Scholar