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Precipitin and Skin Tests as Aids in Diagnosing Trichinosis

Published online by Cambridge University Press:  06 April 2009

Donald L. Augustine  and
Hans Theiler
Donald L. Augustine
Affiliation:
From the Department of Comparative Pathology, George Fabyan Foundation, Medical School and School of Public Health, Harvard University.
Hans Theiler
Affiliation:
From the Department of Comparative Pathology, George Fabyan Foundation, Medical School and School of Public Health, Harvard University.
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Extract

The value of precipitin and intradermal tests as a means of diagnosing trichinosis in man and swine is discussed. The precipitin test appears to be reliable in detecting established trichinosis in swine, and with the conditions under which the observations were made, is highly specific. Established trichinosis in man has been invariably detected by the precipitin test, but its diagnostic value is greatly diminished by the fact that it is also positive with serum from individuals who have recently received quinine treatment for malaria. Certain other drugs appear to affect this reaction in a similar manner. The intradermal test appears to be specific for trichinosis in man and swine when high dilutions of the test antigen are used. The reaction is positive in the early stages of the disease and is of the immediate type in both of these hosts. A survey of swine has shown that the precipitin and intradermal tests are more accurate than muscle examination.

Type
Research Article
Information
Parasitology , Volume 24 , Issue 1 , March 1932 , pp. 60 - 86
Copyright
Copyright © Cambridge University Press 1932

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References

Bachman, G. W. (1928). A precipitin test in experimental trichuriasis. J. Prev. Med. 2, 35.Google Scholar
Bachman, G. W. (1928 a). An intradermal reaction in experimental trichiniasis. J. Prev. Med. 2, 513.Google Scholar
Coventry, F. A. (1929). Hypersensitiveness to helminth proteins. II. Cutaneous and precipitin tests with ascaris extracts in infected and immunised animals. J. Prev. Med. 3, 43.Google Scholar
Coventry, F. A. and Taliaferro, W. H. (1928). Hypersensitiveness to helminth proteins. I. Cutaneous tests with proteins of ascaris, hookworm and trichuris in Honduras. J. Prev. Med. 2, 273.Google Scholar
Fülleborn, F. (1926). Spezifische Kutanreaktionen bei Infektion mit Strongyloides und anderen Helminthen. Arch. f. Schiffs- u. Tropenhyg. 30, 732.Google Scholar
Hunter, S. W. (1931). Human Trichinella spiralis infections and the Bachman precipitin test. Amer. J. Hyg. 13, 311.Google Scholar
Schwartz, B., McIntosh, A. and Mitchell, W. C. (1930). Non-specific skin reactions in pigs to the injection of trichina extracts. (Proc. Amer. Soc. Parasitologists.) J. Parasit. Urbana, 17, 114.Google Scholar
Stoll, H. F. (1929). Trichinosis. J. Amer. Med. Assoc. 92, 791.CrossRefGoogle Scholar
Stoll, N. R. and Nelson, J. B. (1930). Intradermal tests with haemonchus extracts in sheep and goats. (Proc. Amer. Soc. Parasitologists.) J. Parasit. Urbana, 17, 116.CrossRefGoogle Scholar
Stumberg, J. E. (1930). Precipitin and complement-fixation tests on dog sera with antigen from the dog hookworm, Ancylostoma caninum. Amer. J. Hyg. 12, 657.Google Scholar
Stumberg, J. E. and Rodriguez-Molina, R. (1931). Hypersensitiveness to hookworm proteins in Porto Rico. Porto Rico J. Publ. Health and Trop. Med. 7, 37.Google Scholar
Taliaferro, W. H. (1929). The immunology of parasitic infections. Century Company, New York, 414 pp.Google Scholar
Taliaferro, W.H., Hoffman, W. A. and Cook, D. H. (1928). A precipitin test in intestinal schistosomiasis (S. mansoni). J. Prev. Med. 2, 395.Google Scholar
Taliaferro, W. H. and Taliaferro, L. G. (1931). Skin reactions in persons infected with Schistosoma mansoni. Porto Rico J. Publ. Health and Trop. Med. 7, 23.Google Scholar