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Observations on the pathogenicity and pathology of Ascaridia galli

Published online by Cambridge University Press:  06 April 2009

M. M. Ikeme
M. M. Ikeme
Affiliation:
University of Edinburgh, Department of Zoology
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Summary

The pathogenicity and pathology of Ascaridia galli infections of poultry were studied using repeated doses of varying numbers of eggs. No significant effect due to infection was seen on p.c.v. and Hb. values of infected chickens. Haemo concentration occurred parallel with sporadic diarrhoea, which follows high levels of repeated dosing. This phenomenon complicated the interpretation of blood protein values. A/G ratios were, however, worked out and analysed. No significant differences were noticed between the groups and it was concluded that under the levels of inoculation employed during the study there were no significant effects of A. galli infections on blood protein values as well as p.c.v. and Hb.values of infected chickens.

Symptomatic developments, macroscopic lesions and pathological changes of intestinal tissues due to infection were followed up in detail. They were most severe in chickens on the least nutritive diet and sustaining the highest levels of repeated doses. Pathogenicity of larval and adult parasites was described. The presence of large numbers of adult parasites was associated with intestinal obstruction in host. This was seen mostly in chickens on low nutrition and sustaining either low or high levels of repeated inoculation, and very rarely also in chickens under high plane of nutrition but sustaining repeated inoculation of small numbers of eggs. Cellular infiltration as a result of infection was found to be extremely rare.It was present as fibroblasts and only in association with dead larvae.

The author is indebted to the Department of Technical Cooperation, under whose Fellowship the study was carried out; the Department of Zoology, Edinburgh University, for facilities provided; the Ministry of Agriculture, Fisheries and Food; Lasswode Poultry Research Laboratories, for the free supply of chickens used here; Dr J. A. Campbell of Edinburgh University for his keen interest, encouragement and advice throughout this work; and finally to G. Obiwelozor for reproducing the photographs from the original manuscript.

Type
Research Article
Information
Parasitology , Volume 63 , Issue 2 , October 1971 , pp. 169 - 179
Copyright
Copyright © Cambridge University Press 1971

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References

REFERENCES

Ackert, J. E. (1920). Studies on the development of Ascaridia perspicullum parasitic in fowls. Anatomical Record 17, 331–41.Google Scholar
Ackert, J. E. & Wisseman, C. L. (1946). Tolerance of fowls for moderate infections of intestinal helminths. American Journal of Tropical Medicine 26, 721–8.Google Scholar
Allison, J. B. (1955). Biological evaluation of proteins. Physiological Reviews 35, 664–70.CrossRefGoogle ScholarPubMed
Clegg, J. W. & King, E. J. (1942). Estimation of haemoglobin by the alkaline haematin method. British Medical Journal 2, 239–40.CrossRefGoogle ScholarPubMed
Ikeme, M. M. (1971). Weight changes in chickens placed on different levels of nutrition and varying degrees of repeated infection with Ascaridia galli eggs. Parasitology 63, 251–60.CrossRefGoogle ScholarPubMed
Kadziolka, A. (1960). Histopathological studies on the tissue test in experimental Ascaridiasis in chickens. Acta Parasitologica polonica 8, 315–24.Google Scholar
Roberts, F. H. S. (1937). Studies on the biology and control of the large round worm of fowls Ascaridia galli. Queensland Department of Agriculture and Stock Bulletin, no.2.Google Scholar
Ross, J. G. & Armour, J. (1960). The significance of faecal egg counts and the use of serum albumin levels and packed cell volume percentages to assess pathogenicity in helminthiasis. Veterinary Record 72, 137–9.Google Scholar
Sadun, E. H. (1949). The antibody basis of immunity in chickens to the nematode Ascaridia galli. American Journal of Hygiene 49, 101–16.Google Scholar
Sadun, E. H. (1950). The influence of dietary pteroyglutamic acid and of A.P.A. liver extract on the survival and growth of the nematode Ascaridia galli in chickens fed purified and natural diets. American Journal of Hygiene 51, 274–91.Google Scholar
Wiechselbaum, T. E. (1946). Biuret reaction for total protein. American Journal of Clinical Pathology (Technical Section) 10, 40.Google Scholar