Hostname: page-component-78c5997874-g7gxr Total loading time: 0 Render date: 2024-11-02T20:34:12.524Z Has data issue: false hasContentIssue false

Mouse-to-mouse transmission of infections with Giardia muris

Published online by Cambridge University Press:  06 April 2009

M. Belosevic
Affiliation:
Institute of Parasitology, McGill University, 21 111 Lakeshore Rd, Ste Anne-de-Bellevue, Quebec, Canada H9X 1CO
G.M. Faubert
Affiliation:
Institute of Parasitology, McGill University, 21 111 Lakeshore Rd, Ste Anne-de-Bellevue, Quebec, Canada H9X 1CO
J. D. Maclean
Affiliation:
McGill Centre for Tropical Diseases, Montreal General Hospital, Montreal, Quebec

Summary

The transmission of infection with Giardia muris among CD-I mice was quantified by determining the duration of the latent period and intensity of cyst release during the acute phase of the infection. Housing of experimentally inoculated mice with uninfected mice in the same cage resulted in 100% transmission of infection. The dissemination of the infection was faster if experimentally inoculated hosts were passing high numbers of cysts at the time of housing with uninfected animals. The course of ‘naturally’ acquired and experimentally induced infections was similar. We conclude that G. muris has a high transmission potential and that the number of cysts randomly consumed does not influence the course and eventual outcome of the infection.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1986

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Belosevic, M. & Faubert, G. M. (1983a). Temporal study of acquired resistance in infections of mice with Giardia muris. Parasitology 87, 517–24.Google Scholar
Belosevic, M. & Faubert, G. M. (1983b). Giardia muris: correlation between oral dosage, course of infection and trophozoite distribution in the mouse small intestine. Experimental Parasitology 56, 93100.Google Scholar
Erlandsen, S. L. & Meyer, E. A. (1984). Giardia and Giardiasis (ed. Erlandsen, S. L. and Meyer, E. A.). New York: Plenum Press.CrossRefGoogle Scholar
Roberts-Thomson, I. C., Stevens, D. P., Mahmoud, A. A. F. & Warren, K. S. (1976). Giardiasis in the mouse: an animal model. Gastroenterology 71, 5761.Google Scholar