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Epidemiology of canine leishmaniasis: a comparative serological study of dogs and foxes in Amazon Brazil

Published online by Cambridge University Press:  06 April 2009

O. Courtenay ,
D. W. Macdonald ,
R. Lainson ,
J. J. Shaw  and
C. Dyes
O. Courtenay
Affiliation:
Department of Medical Parasitology, London School of Hygiene and Tropical Medicine, Keppel Street, London WCJE 7HT, UK Wildlife Conservation Research Unit, Department of Zoology, South Parks Road, Oxford OXI 3PS, UK
D. W. Macdonald
Affiliation:
Wildlife Conservation Research Unit, Department of Zoology, South Parks Road, Oxford OXI 3PS, UK
R. Lainson
Affiliation:
Wellcome Parasitology Unit, Instituto Evandro Chagas, C. P. 3, 66.000, Belém, Pará, Brazil
J. J. Shaw
Affiliation:
Wellcome Parasitology Unit, Instituto Evandro Chagas, C. P. 3, 66.000, Belém, Pará, Brazil Instituto de Cieências Biomédaicas, Departmento de Parasitologia, Universidade de São Paulo, Brazil
C. Dyes
Affiliation:
Department of Medical Parasitology, London School of Hygiene and Tropical Medicine, Keppel Street, London WCJE 7HT, UK
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Summary

The paper describes a longitudinal field study of canine leishmaniasis in sympatric domestic dog and crab-eating fox (Cerdocyon thous) populations. Dogs were studied in house-to-house surveys, and foxes were studied by live-trapping and radio-telemetry. Because serological tests (IFAT in this case) for leishmaniasis are often of uncertain sensitivity and specificity, we draw conclusions comparatively. Both cross-sectional (age–prevalence) and longitudinal analyses indicate that incidence in dogs was highest in the dry season. Seasonal changes in the age–prevalence relationship for dogs suggest that serological conversion and recovery rates decline with prior exposure to infection, where ‘recovery’ may be due to loss of a positive antibody titre or death from leishmaniasis. The mean incidence in dogs was higher in the rural than in the urban population and higher in hunting dogs than pet dogs. Cross-sectional and longitudinal analyses of fox serological data suggest that foxes remain positive for longer than dogs on average, either because detectable antibody is more persistent or because they experience a lower mortality rate due to leishmaniasis.

Keywords

canine leishmaniasisepidemiologyserologydogCerdocyon thousBrazil
Type
Research Article
Information
Parasitology , Volume 109 , Issue 3 , September 1994 , pp. 273 - 279
Copyright
Copyright © Cambridge University Press 1994

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References

REFERENCES

Corredor, A., Gallego, J. F., Tesh, R. B., Morales, A, De Carrasquilla, C. F., Young, D. C., Kreutzer, R. D., Boshell, J., Palau, M. T., Caceres, E. & Pelaez, D. (1989). Epidemiology of visceral leishmaniasis in Colombia. American Journal of Tropical Medicine and Hygiene 40, 480–6.CrossRefGoogle ScholarPubMed
Da Silva, J. & Macdonald, D. W. (1989). Limitations to the use of tooth wear as a means of ageing Eurasian badgers, Meles metes. Revue d' Ecologie (Terre Vie) 44, 275–8.Google Scholar
Deane, L. M. & Grimaldi, G. Jr (1985). Leishmaniasis in Brazil. In Leishmaniasis (eds. Chang, K. P. & Bray, R. S.), pp. 248–281. Amsterdam: Elsevier Science Publishers.Google Scholar
Doncaster, C. P. & Macdonald, D. W. (1990). Drifting territoriality in the red fox Vulpes vulpes. Journal of Animal Ecology 60, 423–39.CrossRefGoogle Scholar
Dye, C., Killick-Kendrick, R., Vitutia, M. M., Walton, R., Killick-Kendrick, M., Harith, A. E., Guy, M. W., Caavate, M.-C. & Hasibeder, G. (1992). Epidemiology of canine leishmaniasis: prevalence, incidence and basis reproduction number calculated from a cross-sectional serological survey on the island of Gozo, Malta. Parasitology 105, 35–41.CrossRefGoogle Scholar
Dye, C., Vidor, E. & Dereure, J. (1993). Serological diagnosis of leishmaniasis: on detecting infection as well as disease. Epidemiology and Infection 103, 647–56.CrossRefGoogle Scholar
Dye, C. & Williams, B. G. (1993). Malnutrition, age and the risk of parasitic disease: visceral leishmaniasis revisited. Proceedings of the Royal Society of London, B 254, 33–9.Google ScholarPubMed
Evans, T. G., Vasconcelos, I. A. B., Lima, J. W., Texeira, J. M., McAullife, I. T., Lopes, U. G., Pearson, R. D. & Vasconcelos, A. W. (1990). Canine visceral leishmaniasis in northeast Brazil: assessment of serodiagnostic methods. American Journal of Tropical Medicine and Hygiene 42, 118–23.CrossRefGoogle ScholarPubMed
Hancox, M. (1988). Field age determination in the European badger. Revue d' Ecologie (Terre Vie) 43, 399–404.Google Scholar
Harris, S. (1986). Urban Foxes. London: Whitten Books.Google Scholar
Hasibeder, G., Dye, C. & Carpenter, J. (1992). Mathematical modelling and theory for estimating the basic reproduction number of canine leishmaniasis. Parasitology 105, 43–53.CrossRefGoogle ScholarPubMed
Lainson, R., Shaw, J. J., Silveira, F. T. & Braga, R. R. (1987). American visceral leishmaniasis: on the origin of Leishmania (Leishmania) chagasi. Transactions of the Royal Society of Tropical Medicine and Hygiene 81, 517.CrossRefGoogle ScholarPubMed
Lainson, R., Dye, C., Shaw, J. J., Macdonald, D., Courtenay, O., Souza, A. A. & Silveira, F. T. (1990). Amazonian visceral leishmaniasis: distribution of the vector Lutzomyia longipalpis (Lutz & Neiva) in relation to the fox Cerdocyon thous (L.) and the efficiency of this reservoir host as a source of infection. Memorias do Instituto Oswaldo Cruz 85, 135–7.CrossRefGoogle Scholar
Lanotte, G., Rioux, J.-A., Perieres, J. & Vollhardt, Y. (1979). Ecologie des leishmanioses dans le sud de la France. 10. Les formes évolutives de la leishmaniose viscérale canine. Elaboration d'une typologie bioclinique à finalité épidémiologique. Annales de Parasitologie (Paris) 54, 277–95.Google Scholar
Pinelli, E., Killick-Kendrick, R., Wagenaar, J., Bernadina, W., Del Real, C. & Ruitenberg, J. (1994). Cellular and humoral immune response in dogs experimentally and naturally infected with Leishmania infantum. Infection and Immunity 62, 229–35.CrossRefGoogle ScholarPubMed
Pires, J. M. & Prance, G. T. (1985). The vegetation types of the Brazilian Amazon. In Key Environments: Amazonia (ed. Prance, G. T. & Lovejoy, T. E.), pp. 109–145. Oxford: Pergamon Press.Google Scholar
Prance, G. T. (1987). Soils and Vegetation. In Biogeography and Quaternary History in Tropical America (ed. Whitmore, T. C. & Prance, G. T.). Oxford Monographs on Biogeography no. 3, pp. 28–45. Oxford: Oxford Science Publications, Clarendon Press.Google Scholar
Quinnell, R. J. & Dye, C. (1994). Correlates of peridomestic abundance of Lutzomyia longipalpis (Diptera: Psychodidae) in Amazonian Brazil. Medical and Veterinary Entomology 8, in Press.CrossRefGoogle ScholarPubMed
Riley, E. M., Olerup, O. & Troye-Blomberg, M. (1991). The immune recognition of malaria antigens. Parasitology Today 7, 5–11.CrossRefGoogle ScholarPubMed
Rioux, J.-A., Albaret, J.-L., Houin, R., Dedet, J.-P. & Lanotte, G. (1968). Ecologie des leishmanioses dans le sud de la France 2. Les reservoirs silvatiques. Infestation spontane du renard ( Vulpes vulpes L.). Annales de Parasitologie 43, 421–8.Google Scholar
Rioux, J.-A., Lanotte, C., Destombes, P., Vollhardt, Y. & Croset, H. (1971). Leishmaniose exprimentale du renard Vulpes vulpes (L.). Recueil de Medecine Veterinaire 148, 489–98.Google Scholar
Ryan, L., Silveira, F. T., Lainson, R. & Shaw, J. J. (1984). Leishmania infections in Lutzomyia longipalpis and Lu. antunesi (Diptera: Psychodidae) on the island of Marajó, Parà State, Brazil. Transactions of the Royal Society of Tropical Medicine and Hygiene 78, 547–8.CrossRefGoogle ScholarPubMed
Silveira, F. T., Lainson, R., Shaw, J. J. & Povoa, M. M. (1982). Leishmaniasis in Brazil. XVIII. Further evidence incriminating the fox Cerdocyon thous (L.) as a reservior of Amazonian visceral leishmaniasis. Transactions of the Royal Society of Tropical Medicine and Hygiene 76, 830–2.CrossRefGoogle Scholar
Van Bree, P. J. H., Van Soest, R. W. M. & Stroman, L. (1974). Tooth wear as an indication of age in badgers (Meles meles L.) and red foxes ( Vulpes vulpes L.). Zeitschrift für Saugetierkunde 39, 243–8.Google Scholar
Vidor, E., Dereure, J., Pratlong, F., Dubruil, N., Bissuel, C., Moreau, Y. & Rioux, J.-A. (1991). Le chancre d'inoculation dans la leishmaniose canine a Leishmania infantum: étude d'une cohorte en région cévenole. Pratique Medicale et Chirurgicale de l' Animal de Compagnie 26, 133–7.Google Scholar