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The development of drug-resistant strains of Eimeria maxima in the laboratory

Published online by Cambridge University Press:  06 April 2009

C. C. Norton  and
L. P. Joyner
C. C. Norton
Affiliation:
Central Veterinary Laboratory, MAFF, New Haw, Weybridge, Surrey
L. P. Joyner
Affiliation:
Central Veterinary Laboratory, MAFF, New Haw, Weybridge, Surrey
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Extract

The development of strains of Eimeria maxima resistant to buquinolate, methyl benzoquate, clopidol, sulphaquinoxaline and robenidine is described. It was not possible to standardize a schedule of inoculations and drug administration, which would enable the development of resistance to the different drugs to be compared directly. Resistance developed most readily to the quinolones. One robenidine-resistant strain proved to be drug-dependent. Dinitolmide showed unusual effects upon sporogony and three attempts to develop resistance against this activity failed. Chicks previously immunized with the parent strain were completely protected against infection with the drug-resistant strains.

Type
Research Article
Information
Parasitology , Volume 71 , Issue 1 , August 1975 , pp. 153 - 165
Copyright
Copyright © Cambridge University Press 1975

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References

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